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A0A1A0H6S3 A0A1A0H6S3 A0A1A0H6S7 A0A1A0H6S7 A0A1A0H6Y2 A0A1A0H6Y2 A0A1A0H743 A0A1A0H743 A0A1A0H7A1 A0A1A0H7A1 A0A1A0H7X2 A0A1A0H7X2 A0A1A0H7Y1 A0A1A0H7Y1 A0A1A0H7Z7 A0A1A0H7Z7 A0A1A0H806 A0A1A0H806 A0A1A0H8C5 A0A1A0H8C5 A0A1A0H8F3 A0A1A0H8F3 A0A1A0H8K0 A0A1A0H8K0 A0A1A0H8S6 A0A1A0H8S6 A0A1A0H9K5 A0A1A0H9K5 A0A1A0H9L5 A0A1A0H9L5 A0A1A0HA68 A0A1A0HA68 A0A1A0HAQ5 A0A1A0HAQ5 A0A1A0HAU3 A0A1A0HAU3 A0A1A0HBZ1 A0A1A0HBZ1 A0A1A0HC29 A0A1A0HC29 A0A1A0HC44 A0A1A0HC44 A0A1A0HD30 A0A1A0HD30 A0A1A0HD71 A0A1A0HD71 A0A1A0HDD4 A0A1A0HDD4 A0A1A0HDH5 A0A1A0HDH5 A0A1A0HDR9 A0A1A0HDR9 A0A1A0HE00 A0A1A0HE00 A0A1A0HE56 A0A1A0HE56 A0A1A0HED5 A0A1A0HED5 A0A1A0HFA2 A0A1A0HFA2 A0A1A0HFE6 A0A1A0HFE6 A0A1A0HFG3 A0A1A0HFG3 A0A1A0HFL1 A0A1A0HFL1 A0A1A0HFW8 A0A1A0HFW8 A0A1A0HG15 A0A1A0HG15 A0A1A0HGC0 A0A1A0HGC0 A0A1A0HH80 A0A1A0HH80 A0A1A0HHA4 A0A1A0HHA4 A0A1A0HHU6 A0A1A0HHU6 A0A1A0HHY4 A0A1A0HHY4 MCM7 MCM7 A0A1A0HID9 A0A1A0HID9 A0A1A0HJ01 A0A1A0HJ01 A0A1A0HJC7 A0A1A0HJC7 A0A1A0HJI0 A0A1A0HJI0 A0A1A0HJL9 A0A1A0HJL9 A0A1A0HJN6 A0A1A0HJN6 A0A1A0HK04 A0A1A0HK04 A0A1A0HKE2 A0A1A0HKE2 A0A1A0HKG5 A0A1A0HKG5 A0A1A0HKU1 A0A1A0HKU1 A0A1A0H512 A0A1A0H512 A0A1A0HKY9 A0A1A0HKY9 A0A1A0H5C8 A0A1A0H5C8 A0A1A0H614 A0A1A0H614 A0A1A0H684 A0A1A0H684 A0A1A0H4X2 A0A1A0H4X2 A0A1A0H4G2 A0A1A0H4G2 A0A1A0H2A0 A0A1A0H2A0 A0A1A0H262 A0A1A0H262 A0A1A0H211 A0A1A0H211 A0A1A0H1Z5 A0A1A0H1Z5 A0A1A0GZ83 A0A1A0GZ83 A0A1A0GZ55 A0A1A0GZ55 A0A1A0H6J9 A0A1A0H6J9 A0A1A0H6K1 A0A1A0H6K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1A0H6S3Histone H2A; Belongs to the histone H2A family. (133 aa)
A0A1A0H6S7ANK_REP_REGION domain-containing protein. (1077 aa)
A0A1A0H6Y2DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (795 aa)
A0A1A0H743RNI-like protein. (416 aa)
A0A1A0H7A1Uncharacterized protein. (738 aa)
A0A1A0H7X2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (990 aa)
A0A1A0H7Y1Zf-primase domain-containing protein. (505 aa)
A0A1A0H7Z7ORC_WH_C domain-containing protein. (723 aa)
A0A1A0H806Uncharacterized protein. (1204 aa)
A0A1A0H8C5tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (465 aa)
A0A1A0H8F3Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1435 aa)
A0A1A0H8K0AAA_16 domain-containing protein. (479 aa)
A0A1A0H8S6Isochorismatase hydrolase. (234 aa)
A0A1A0H9K5Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (250 aa)
A0A1A0H9L5Uncharacterized protein. (560 aa)
A0A1A0HA68Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (256 aa)
A0A1A0HAQ5RFX-type winged-helix domain-containing protein. (640 aa)
A0A1A0HAU3Uncharacterized protein. (330 aa)
A0A1A0HBZ1Histone H2B; Belongs to the histone H2B family. (130 aa)
A0A1A0HC29Uncharacterized protein. (1978 aa)
A0A1A0HC44Rad60-SLD domain-containing protein. (390 aa)
A0A1A0HD30SPT2-domain-containing protein. (368 aa)
A0A1A0HD71Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1A0HDD4Uncharacterized protein. (1042 aa)
A0A1A0HDH5Histone H1/H5. (70 aa)
A0A1A0HDR9Uncharacterized protein. (653 aa)
A0A1A0HE00FK506-binding protein. (438 aa)
A0A1A0HE56Rtt106-domain-containing protein. (498 aa)
A0A1A0HED5Histone-fold-containing protein. (199 aa)
A0A1A0HFA2Cysteine proteinase; Belongs to the peptidase C19 family. (668 aa)
A0A1A0HFE6Peptidase S59 domain-containing protein. (1401 aa)
A0A1A0HFG3WD40 repeat-like protein. (430 aa)
A0A1A0HFL1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
A0A1A0HFW8SIR2-domain-containing protein. (515 aa)
A0A1A0HG15Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
A0A1A0HGC0Uncharacterized protein. (1153 aa)
A0A1A0HH80Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (793 aa)
A0A1A0HHA4PHD-type domain-containing protein. (383 aa)
A0A1A0HHU6Origin recognition complex, subunit 6. (380 aa)
A0A1A0HHY4NAP-domain-containing protein; Belongs to the nucleosome assembly protein (NAP) family. (404 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (780 aa)
A0A1A0HID9RanBD1 domain-containing protein. (446 aa)
A0A1A0HJ01DNA helicase; Belongs to the MCM family. (727 aa)
A0A1A0HJC7WD40 repeat-like protein. (395 aa)
A0A1A0HJI0Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (347 aa)
A0A1A0HJL9SPT16-domain-containing protein. (1031 aa)
A0A1A0HJN6WAC domain-containing protein. (1205 aa)
A0A1A0HK04GATA-type domain-containing protein. (757 aa)
A0A1A0HKE2Uncharacterized protein. (1156 aa)
A0A1A0HKG5Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (405 aa)
A0A1A0HKU1Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (978 aa)
A0A1A0H512Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1124 aa)
A0A1A0HKY9Uncharacterized protein. (213 aa)
A0A1A0H5C8DNA helicase; Belongs to the MCM family. (840 aa)
A0A1A0H614B30.2/SPRY domain-containing protein. (456 aa)
A0A1A0H684WD40 repeat-like protein. (442 aa)
A0A1A0H4X2MRC1 domain-containing protein. (1071 aa)
A0A1A0H4G2DnaJ-domain-containing protein. (272 aa)
A0A1A0H2A0DHS-like NAD/FAD-binding domain-containing protein. (497 aa)
A0A1A0H262Uncharacterized protein. (593 aa)
A0A1A0H211Uncharacterized protein. (344 aa)
A0A1A0H1Z5Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (422 aa)
A0A1A0GZ83Putative histone deacetylase-like protein. (288 aa)
A0A1A0GZ55Checkpoint protein; Belongs to the HUS1 family. (338 aa)
A0A1A0H6J9AAA domain-containing protein. (461 aa)
A0A1A0H6K1SHNi-TPR domain-containing protein. (378 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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