STRINGSTRING
A0A1A0HD47 A0A1A0HD47 A0A1A0HDF7 A0A1A0HDF7 A0A1A0HDG0 A0A1A0HDG0 A0A1A0HDZ1 A0A1A0HDZ1 A0A1A0HE14 A0A1A0HE14 A0A1A0HE18 A0A1A0HE18 A0A1A0HE23 A0A1A0HE23 A0A1A0HE50 A0A1A0HE50 A0A1A0HEC5 A0A1A0HEC5 A0A1A0HCS1 A0A1A0HCS1 A0A1A0HD92 A0A1A0HD92 A0A1A0HKQ4 A0A1A0HKQ4 A0A1A0HKF6 A0A1A0HKF6 A0A1A0HKE3 A0A1A0HKE3 A0A1A0HK15 A0A1A0HK15 A0A1A0HJR1 A0A1A0HJR1 A0A1A0HJC1 A0A1A0HJC1 A0A1A0HJ75 A0A1A0HJ75 A0A1A0HJ36 A0A1A0HJ36 A0A1A0HJ22 A0A1A0HJ22 A0A1A0HIZ0 A0A1A0HIZ0 A0A1A0HIY8 A0A1A0HIY8 NCS6 NCS6 A0A1A0HIQ9 A0A1A0HIQ9 A0A1A0HIJ5 A0A1A0HIJ5 A0A1A0HIG6 A0A1A0HIG6 A0A1A0HIG1 A0A1A0HIG1 A0A1A0HIF5 A0A1A0HIF5 NCS2 NCS2 A0A1A0HIB7 A0A1A0HIB7 A0A1A0HIB4 A0A1A0HIB4 A0A1A0HHZ3 A0A1A0HHZ3 A0A1A0HHY2 A0A1A0HHY2 A0A1A0HHV5 A0A1A0HHV5 A0A1A0HHP4 A0A1A0HHP4 A0A1A0HHN5 A0A1A0HHN5 A0A1A0HHM0 A0A1A0HHM0 A0A1A0HHI0 A0A1A0HHI0 A0A1A0HHE3 A0A1A0HHE3 A0A1A0HHD7 A0A1A0HHD7 A0A1A0HHB9 A0A1A0HHB9 A0A1A0HH90 A0A1A0HH90 A0A1A0HH78 A0A1A0HH78 A0A1A0HH58 A0A1A0HH58 A0A1A0HH34 A0A1A0HH34 A0A1A0HGY8 A0A1A0HGY8 A0A1A0HGW4 A0A1A0HGW4 A0A1A0HGU1 A0A1A0HGU1 A0A1A0HGF5 A0A1A0HGF5 A0A1A0HGF2 A0A1A0HGF2 A0A1A0HGA6 A0A1A0HGA6 A0A1A0HG79 A0A1A0HG79 A0A1A0HG15 A0A1A0HG15 A0A1A0HFZ8 A0A1A0HFZ8 A0A1A0HFU9 A0A1A0HFU9 A0A1A0HFR5 A0A1A0HFR5 A0A1A0HFQ7 A0A1A0HFQ7 A0A1A0HFP8 A0A1A0HFP8 A0A1A0HFB1 A0A1A0HFB1 A0A1A0HEP4 A0A1A0HEP4 A0A1A0HEK3 A0A1A0HEK3 A0A1A0HEI1 A0A1A0HEI1 A0A1A0HEG1 A0A1A0HEG1 A0A1A0H4R8 A0A1A0H4R8 A0A1A0H4W0 A0A1A0H4W0 A0A1A0H4X4 A0A1A0H4X4 A0A1A0H570 A0A1A0H570 A0A1A0H5N4 A0A1A0H5N4 A0A1A0H643 A0A1A0H643 A0A1A0H697 A0A1A0H697 A0A1A0H6J1 A0A1A0H6J1 A0A1A0H6M2 A0A1A0H6M2 A0A1A0H6M4 A0A1A0H6M4 A0A1A0H6T1 A0A1A0H6T1 A0A1A0H6U0 A0A1A0H6U0 A0A1A0H6Z5 A0A1A0H6Z5 A0A1A0H708 A0A1A0H708 A0A1A0H732 A0A1A0H732 A0A1A0H735 A0A1A0H735 A0A1A0H7B0 A0A1A0H7B0 A0A1A0H7J1 A0A1A0H7J1 A0A1A0H7J2 A0A1A0H7J2 A0A1A0H7R8 A0A1A0H7R8 A0A1A0H7T4 A0A1A0H7T4 A0A1A0H7V4 A0A1A0H7V4 URM1 URM1 A0A1A0H872 A0A1A0H872 A0A1A0H883 A0A1A0H883 A0A1A0H8A3 A0A1A0H8A3 A0A1A0H8I5 A0A1A0H8I5 A0A1A0H8L7 A0A1A0H8L7 A0A1A0H8R9 A0A1A0H8R9 A0A1A0H8W8 A0A1A0H8W8 A0A1A0H911 A0A1A0H911 A0A1A0H979 A0A1A0H979 A0A1A0H9K5 A0A1A0H9K5 A0A1A0H9P9 A0A1A0H9P9 A0A1A0H9Y5 A0A1A0H9Y5 A0A1A0HA99 A0A1A0HA99 A0A1A0HAA0 A0A1A0HAA0 A0A1A0HAE7 A0A1A0HAE7 A0A1A0HAK7 A0A1A0HAK7 A0A1A0HAL6 A0A1A0HAL6 A0A1A0HAU1 A0A1A0HAU1 A0A1A0HAW9 A0A1A0HAW9 A0A1A0HB94 A0A1A0HB94 A0A1A0HBA3 A0A1A0HBA3 A0A1A0HBM8 A0A1A0HBM8 A0A1A0HBN0 A0A1A0HBN0 UBA4 UBA4 A0A1A0HC21 A0A1A0HC21 A0A1A0HC22 A0A1A0HC22 A0A1A0HC44 A0A1A0HC44 A0A1A0HC73 A0A1A0HC73 A0A1A0HCD3 A0A1A0HCD3 A0A1A0HCM3 A0A1A0HCM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1A0HD47UBC-like protein. (162 aa)
A0A1A0HDF7TPR-like protein. (579 aa)
A0A1A0HDG0CLTH domain-containing protein. (537 aa)
A0A1A0HDZ1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1740 aa)
A0A1A0HE14UBC-like protein. (238 aa)
A0A1A0HE18Uncharacterized protein. (399 aa)
A0A1A0HE23E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1891 aa)
A0A1A0HE50SMAD/FHA domain-containing protein. (235 aa)
A0A1A0HEC5U-box domain-containing protein. (965 aa)
A0A1A0HCS1Uncharacterized protein. (1393 aa)
A0A1A0HD92Uncharacterized protein. (758 aa)
A0A1A0HKQ4CULLIN_2 domain-containing protein; Belongs to the cullin family. (760 aa)
A0A1A0HKF6CULLIN_2 domain-containing protein; Belongs to the cullin family. (785 aa)
A0A1A0HKE3Uncharacterized protein. (352 aa)
A0A1A0HK15RING-type domain-containing protein. (130 aa)
A0A1A0HJR1U-box domain-containing protein. (1033 aa)
A0A1A0HJC1RING-type domain-containing protein. (531 aa)
A0A1A0HJ75FYVE-domain-containing protein. (326 aa)
A0A1A0HJ36WD40 repeat-like protein. (811 aa)
A0A1A0HJ22RING-type domain-containing protein. (613 aa)
A0A1A0HIZ0ThiF domain-containing protein. (345 aa)
A0A1A0HIY8MYND-type domain-containing protein. (821 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (398 aa)
A0A1A0HIQ9Uncharacterized protein. (887 aa)
A0A1A0HIJ5Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
A0A1A0HIG6HECT-domain-containing protein. (785 aa)
A0A1A0HIG1E2_bind domain-containing protein. (428 aa)
A0A1A0HIF5Uncharacterized protein. (2451 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (429 aa)
A0A1A0HIB7TPR-like protein. (703 aa)
A0A1A0HIB4SP-RING-type domain-containing protein. (278 aa)
A0A1A0HHZ3NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (520 aa)
A0A1A0HHY2RING-type domain-containing protein. (1575 aa)
A0A1A0HHV5Uncharacterized protein. (461 aa)
A0A1A0HHP4RING-type domain-containing protein. (326 aa)
A0A1A0HHN5Uncharacterized protein. (1540 aa)
A0A1A0HHM0DNA repair protein rad18. (419 aa)
A0A1A0HHI0RBR-type E3 ubiquitin transferase. (586 aa)
A0A1A0HHE3TPR-like protein. (684 aa)
A0A1A0HHD7Uncharacterized protein. (612 aa)
A0A1A0HHB9Uncharacterized protein. (738 aa)
A0A1A0HH90UBX domain-containing protein. (438 aa)
A0A1A0HH78Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family. (1018 aa)
A0A1A0HH58RING/U-box. (135 aa)
A0A1A0HH34ZZ-type domain-containing protein. (603 aa)
A0A1A0HGY8RNI-like protein. (727 aa)
A0A1A0HGW4RNI-like protein. (563 aa)
A0A1A0HGU1HECT domain-containing protein. (1400 aa)
A0A1A0HGF5Ubiquitin-like protein. (90 aa)
A0A1A0HGF2RING/U-box. (126 aa)
A0A1A0HGA6ANAPC5 domain-containing protein. (808 aa)
A0A1A0HG79Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
A0A1A0HG15Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
A0A1A0HFZ8DWNN-domain-containing protein. (450 aa)
A0A1A0HFU9RING-type domain-containing protein. (309 aa)
A0A1A0HFR5RBR-type E3 ubiquitin transferase. (474 aa)
A0A1A0HFQ7Uncharacterized protein. (115 aa)
A0A1A0HFP8UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
A0A1A0HFB1UBC-like protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
A0A1A0HEP4Prp19-domain-containing protein. (474 aa)
A0A1A0HEK3Not3-domain-containing protein. (499 aa)
A0A1A0HEI1Uncharacterized protein. (1257 aa)
A0A1A0HEG1E3 ubiquitin-protein ligase PEP5. (997 aa)
A0A1A0H4R8UBC-like protein. (137 aa)
A0A1A0H4W0Uncharacterized protein. (455 aa)
A0A1A0H4X4NOT2_3_5 domain-containing protein. (212 aa)
A0A1A0H570RING-type domain-containing protein. (792 aa)
A0A1A0H5N4Uncharacterized protein. (219 aa)
A0A1A0H643HECT domain-containing protein. (957 aa)
A0A1A0H697UBR-type domain-containing protein. (391 aa)
A0A1A0H6J1CLTH domain-containing protein. (489 aa)
A0A1A0H6M2Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (611 aa)
A0A1A0H6M4CULLIN_2 domain-containing protein; Belongs to the cullin family. (623 aa)
A0A1A0H6T1TIP120 domain-containing protein. (1205 aa)
A0A1A0H6U0WD40 repeat-like protein. (747 aa)
A0A1A0H6Z5Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (328 aa)
A0A1A0H708SCF complex F-box protein MET30. (638 aa)
A0A1A0H732Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
A0A1A0H735Uncharacterized protein. (733 aa)
A0A1A0H7B0RING-type domain-containing protein. (402 aa)
A0A1A0H7J1Ubiquitin-like protein. (77 aa)
A0A1A0H7J2Uncharacterized protein. (1709 aa)
A0A1A0H7R8SP-RING-type domain-containing protein. (545 aa)
A0A1A0H7T4UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
A0A1A0H7V4Replication protein A, subunit RPA32. (258 aa)
URM1Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (100 aa)
A0A1A0H872RING-type domain-containing protein. (443 aa)
A0A1A0H883E3 ubiquitin ligase SCF complex, Skp subunit; Belongs to the SKP1 family. (167 aa)
A0A1A0H8A3Galactose-binding like protein. (347 aa)
A0A1A0H8I5Uncharacterized protein. (673 aa)
A0A1A0H8L7Uncharacterized protein. (747 aa)
A0A1A0H8R9Uncharacterized protein. (581 aa)
A0A1A0H8W8Cullin-domain-containing protein; Belongs to the cullin family. (914 aa)
A0A1A0H911RING-type domain-containing protein. (424 aa)
A0A1A0H979Ubiquitin. (79 aa)
A0A1A0H9K5Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (250 aa)
A0A1A0H9P9UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
A0A1A0H9Y5Uncharacterized protein. (884 aa)
A0A1A0HA99General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (473 aa)
A0A1A0HAA0E3 ubiquitin-protein ligase. (762 aa)
A0A1A0HAE7HECT domain-containing protein. (844 aa)
A0A1A0HAK7Uncharacterized protein. (272 aa)
A0A1A0HAL6E3 ubiquitin protein ligase. (679 aa)
A0A1A0HAU1Uncharacterized protein. (565 aa)
A0A1A0HAW9RING-type domain-containing protein. (515 aa)
A0A1A0HB94Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
A0A1A0HBA3Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
A0A1A0HBM8RING-type domain-containing protein. (292 aa)
A0A1A0HBN0Uncharacterized protein. (1484 aa)
UBA4Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...] (397 aa)
A0A1A0HC21Uncharacterized protein. (1497 aa)
A0A1A0HC22Uncharacterized protein. (320 aa)
A0A1A0HC44Rad60-SLD domain-containing protein. (390 aa)
A0A1A0HC73Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. (567 aa)
A0A1A0HCD3RING-type domain-containing protein. (539 aa)
A0A1A0HCM3RING-type domain-containing protein. (201 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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