(26 nodes) Protein targeting to ER network (Metschnikowia bicuspidata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1A0H591	Uncharacterized protein. (554 aa)
	A0A1A0H5J1	GTP binding signal recognition particle receptor. (543 aa)
	A0A1A0H5Z6	P-loop containing nucleoside triphosphate hydrolase protein. (281 aa)
	A0A1A0H6M8	SRP19-domain-containing protein. (270 aa)
	A0A1A0H8Q3	WSC domain-containing protein. (456 aa)
	A0A1A0H940	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (585 aa)
	A0A1A0HB30	ICE2-domain-containing protein. (458 aa)
	A0A1A0HC74	Protein transport protein SEC61 alpha subunit. (478 aa)
	A0A1A0HDJ2	DUF410-domain-containing protein. (317 aa)
	A0A1A0HDW6	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (90 aa)
	A0A1A0HE75	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (555 aa)
	A0A1A0HEA1	Uncharacterized protein. (201 aa)
	A0A1A0HEI4	Uncharacterized protein. (169 aa)
	A0A1A0HEJ8	Translocation protein SEC62. (291 aa)
	A0A1A0HFV4	Protein translocase SEC6. (67 aa)
	A0A1A0HG83	Inorganic phosphate transport PHO88. (191 aa)
	A0A1A0HGC7	Signal peptidase subunit 3. (189 aa)
	A0A1A0HGL1	SecY protein; Belongs to the SecY/SEC61-alpha family. (491 aa)
	A0A1A0HHL1	Signal recognition particle, SRP9/SRP14 subunit. (116 aa)
	A0A1A0HHL7	Uncharacterized protein. (200 aa)
	A0A1A0HHR9	Uncharacterized protein. (88 aa)
	A0A1A0HHX3	Actin-like ATPase domain-containing protein. (919 aa)
	A0A1A0HIP5	SRP9-21 domain-containing protein. (134 aa)
	A0A1A0HIT2	Uncharacterized protein. (165 aa)
	A0A1A0HJM4	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (668 aa)
	A0A1A0HKW0	J domain-containing protein. (664 aa)

Your Current Organism:

Metschnikowia bicuspidata

NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1A0H591	A0A1A0HDJ2	Uncharacterized protein.	DUF410-domain-containing protein.	0.941
A0A1A0H591	A0A1A0HDW6	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.801
A0A1A0H591	A0A1A0HFV4	Uncharacterized protein.	Protein translocase SEC6.	0.637
A0A1A0H591	A0A1A0HHX3	Uncharacterized protein.	Actin-like ATPase domain-containing protein.	0.632
A0A1A0H591	A0A1A0HIT2	Uncharacterized protein.	Uncharacterized protein.	0.699
A0A1A0H5J1	A0A1A0H5Z6	GTP binding signal recognition particle receptor.	P-loop containing nucleoside triphosphate hydrolase protein.	0.996
A0A1A0H5J1	A0A1A0H6M8	GTP binding signal recognition particle receptor.	SRP19-domain-containing protein.	0.943
A0A1A0H5J1	A0A1A0H940	GTP binding signal recognition particle receptor.	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.	0.956
A0A1A0H5J1	A0A1A0HC74	GTP binding signal recognition particle receptor.	Protein transport protein SEC61 alpha subunit.	0.913
A0A1A0H5J1	A0A1A0HDW6	GTP binding signal recognition particle receptor.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.481
A0A1A0H5J1	A0A1A0HE75	GTP binding signal recognition particle receptor.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.998
A0A1A0H5J1	A0A1A0HEJ8	GTP binding signal recognition particle receptor.	Translocation protein SEC62.	0.450
A0A1A0H5J1	A0A1A0HFV4	GTP binding signal recognition particle receptor.	Protein translocase SEC6.	0.627
A0A1A0H5J1	A0A1A0HGL1	GTP binding signal recognition particle receptor.	SecY protein; Belongs to the SecY/SEC61-alpha family.	0.888
A0A1A0H5J1	A0A1A0HHL1	GTP binding signal recognition particle receptor.	Signal recognition particle, SRP9/SRP14 subunit.	0.881
A0A1A0H5J1	A0A1A0HIP5	GTP binding signal recognition particle receptor.	SRP9-21 domain-containing protein.	0.918
A0A1A0H5J1	A0A1A0HJM4	GTP binding signal recognition particle receptor.	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.	0.965
A0A1A0H5J1	A0A1A0HKW0	GTP binding signal recognition particle receptor.	J domain-containing protein.	0.515
A0A1A0H5Z6	A0A1A0H5J1	P-loop containing nucleoside triphosphate hydrolase protein.	GTP binding signal recognition particle receptor.	0.996
A0A1A0H5Z6	A0A1A0H6M8	P-loop containing nucleoside triphosphate hydrolase protein.	SRP19-domain-containing protein.	0.908