STRINGSTRING
A0A1A0H202 A0A1A0H202 A0A1A0H6Y9 A0A1A0H6Y9 A0A1A0H758 A0A1A0H758 A0A1A0H7S3 A0A1A0H7S3 A0A1A0H855 A0A1A0H855 A0A1A0H863 A0A1A0H863 A0A1A0H8K1 A0A1A0H8K1 A0A1A0H8T5 A0A1A0H8T5 A0A1A0HA06 A0A1A0HA06 A0A1A0HAF4 A0A1A0HAF4 DRE2 DRE2 A0A1A0HB01 A0A1A0HB01 A0A1A0HB55 A0A1A0HB55 A0A1A0HCT6 A0A1A0HCT6 A0A1A0HD23 A0A1A0HD23 A0A1A0HDT5 A0A1A0HDT5 A0A1A0HDY9 A0A1A0HDY9 A0A1A0HE13 A0A1A0HE13 A0A1A0HEA7 A0A1A0HEA7 A0A1A0HFH4 A0A1A0HFH4 NBP35 NBP35 A0A1A0HGT1 A0A1A0HGT1 A0A1A0HHD5 A0A1A0HHD5 A0A1A0HHE6 A0A1A0HHE6 CFD1 CFD1 A0A1A0HID2 A0A1A0HID2 A0A1A0HJD4 A0A1A0HJD4 A0A1A0HJG7 A0A1A0HJG7 A0A1A0HJU6 A0A1A0HJU6 A0A1A0HJY1 A0A1A0HJY1 A0A1A0HK46 A0A1A0HK46 A0A1A0HKD6 A0A1A0HKD6 A0A1A0HKX6 A0A1A0HKX6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1A0H202DNA polymerase. (1067 aa)
A0A1A0H6Y9NADH-ubiquinone oxidoreductase 49 kDa subunit mitochondrial; Belongs to the complex I 49 kDa subunit family. (453 aa)
A0A1A0H758Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (684 aa)
A0A1A0H7S3Iron hydrogenase; Belongs to the NARF family. (528 aa)
A0A1A0H855Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (802 aa)
A0A1A0H863DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2228 aa)
A0A1A0H8K13-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
A0A1A0H8T5NADH-quinone oxidoreductase; Belongs to the complex I 20 kDa subunit family. (187 aa)
A0A1A0HA06Fe-S_biosyn domain-containing protein. (174 aa)
A0A1A0HAF4DNA polymerase. (1459 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (334 aa)
A0A1A0HB01NADH dehydrogenase 78K chain, 5-prime end; Belongs to the complex I 75 kDa subunit family. (699 aa)
A0A1A0HB55NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (482 aa)
A0A1A0HCT6Biotin synthase. (375 aa)
A0A1A0HD23HIRA-interacting protein 5. (252 aa)
A0A1A0HDT5Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (779 aa)
A0A1A0HDY92-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (564 aa)
A0A1A0HE13Lipoyl synthase. (259 aa)
A0A1A0HEA7Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (260 aa)
A0A1A0HFH42-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (407 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NB [...] (325 aa)
A0A1A0HGT1Uncharacterized protein. (95 aa)
A0A1A0HHD5Mitochondrial complex I NUIM TYKY subunit. (222 aa)
A0A1A0HHE6P-loop containing nucleoside triphosphate hydrolase protein. (316 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD [...] (294 aa)
A0A1A0HID2Uncharacterized protein. (546 aa)
A0A1A0HJD4Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (622 aa)
A0A1A0HJG7Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (548 aa)
A0A1A0HJU6HIRA-interacting protein 5. (253 aa)
A0A1A0HJY1DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (515 aa)
A0A1A0HK46Flavodoxin-like domain-containing protein. (714 aa)
A0A1A0HKD6DNA polymerase. (1580 aa)
A0A1A0HKX6DNA helicase component of transcription factor b. (795 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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