STRINGSTRING
A0A1A0HKI5 A0A1A0HKI5 A0A1A0HGC5 A0A1A0HGC5 A0A1A0H270 A0A1A0H270 A0A1A0HFQ4 A0A1A0HFQ4 A0A1A0HFL1 A0A1A0HFL1 A0A1A0HFJ6 A0A1A0HFJ6 A0A1A0HFI2 A0A1A0HFI2 A0A1A0HFD9 A0A1A0HFD9 A0A1A0HFB3 A0A1A0HFB3 A0A1A0HEW3 A0A1A0HEW3 A0A1A0HEV2 A0A1A0HEV2 A0A1A0HEC7 A0A1A0HEC7 A0A1A0HEB9 A0A1A0HEB9 A0A1A0HDY3 A0A1A0HDY3 A0A1A0HDI8 A0A1A0HDI8 A0A1A0HBZ1 A0A1A0HBZ1 A0A1A0HDG1 A0A1A0HDG1 A0A1A0HD71 A0A1A0HD71 A0A1A0H4N1 A0A1A0H4N1 A0A1A0H4T9 A0A1A0H4T9 A0A1A0H594 A0A1A0H594 A0A1A0H5C8 A0A1A0H5C8 A0A1A0H5F8 A0A1A0H5F8 A0A1A0H5W2 A0A1A0H5W2 A0A1A0H5W8 A0A1A0H5W8 A0A1A0H600 A0A1A0H600 A0A1A0H652 A0A1A0H652 A0A1A0H6M2 A0A1A0H6M2 A0A1A0H6S3 A0A1A0H6S3 A0A1A0H6X8 A0A1A0H6X8 A0A1A0H6Y2 A0A1A0H6Y2 A0A1A0H6Y3 A0A1A0H6Y3 A0A1A0H710 A0A1A0H710 A0A1A0H712 A0A1A0H712 A0A1A0H775 A0A1A0H775 A0A1A0H7U8 A0A1A0H7U8 A0A1A0H7X2 A0A1A0H7X2 A0A1A0H829 A0A1A0H829 A0A1A0H840 A0A1A0H840 A0A1A0H863 A0A1A0H863 A0A1A0H8X1 A0A1A0H8X1 A0A1A0H953 A0A1A0H953 A0A1A0H9I1 A0A1A0H9I1 A0A1A0H9Q7 A0A1A0H9Q7 A0A1A0H9T5 A0A1A0H9T5 A0A1A0H9X3 A0A1A0H9X3 A0A1A0H9Z1 A0A1A0H9Z1 A0A1A0HAF4 A0A1A0HAF4 A0A1A0HAU0 A0A1A0HAU0 A0A1A0HAY5 A0A1A0HAY5 A0A1A0HBC9 A0A1A0HBC9 A0A1A0HBF9 A0A1A0HBF9 A0A1A0HBW3 A0A1A0HBW3 A0A1A0HCU1 A0A1A0HCU1 A0A1A0HCR0 A0A1A0HCR0 A0A1A0HCQ1 A0A1A0HCQ1 A0A1A0HCG0 A0A1A0HCG0 A0A1A0HC99 A0A1A0HC99 A0A1A0HC01 A0A1A0HC01 A0A1A0H202 A0A1A0H202 A0A1A0HKI3 A0A1A0HKI3 A0A1A0HKD6 A0A1A0HKD6 A0A1A0HJZ4 A0A1A0HJZ4 A0A1A0HJY1 A0A1A0HJY1 A0A1A0HJK9 A0A1A0HJK9 A0A1A0HJ01 A0A1A0HJ01 A0A1A0HIK2 A0A1A0HIK2 A0A1A0HBY7 A0A1A0HBY7 A0A1A0HIE3 A0A1A0HIE3 MCM7 MCM7 A0A1A0HI73 A0A1A0HI73 A0A1A0HHK8 A0A1A0HHK8 A0A1A0HH54 A0A1A0HH54 A0A1A0HGN6 A0A1A0HGN6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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A0A1A0HKI5DNA helicase; Belongs to the MCM family. (940 aa)
A0A1A0HGC5HMG box domain-containing protein. (89 aa)
A0A1A0H270DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1165 aa)
A0A1A0HFQ4Uncharacterized protein. (611 aa)
A0A1A0HFL1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
A0A1A0HFJ6Zn(2)-C6 fungal-type domain-containing protein. (1057 aa)
A0A1A0HFI2DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1132 aa)
A0A1A0HFD9Histone-fold-containing protein. (141 aa)
A0A1A0HFB3Uncharacterized protein. (139 aa)
A0A1A0HEW3NDT80 domain-containing protein. (771 aa)
A0A1A0HEV2Zn(2)-C6 fungal-type domain-containing protein. (927 aa)
A0A1A0HEC7Fork-head domain-containing protein. (499 aa)
A0A1A0HEB9Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (580 aa)
A0A1A0HDY3Alpha box domain-containing protein. (176 aa)
A0A1A0HDI8Zn(2)-C6 fungal-type domain-containing protein. (936 aa)
A0A1A0HBZ1Histone H2B; Belongs to the histone H2B family. (130 aa)
A0A1A0HDG1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (915 aa)
A0A1A0HD71Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1A0H4N1HSF_DOMAIN domain-containing protein. (606 aa)
A0A1A0H4T9DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1398 aa)
A0A1A0H594Winged helix DNA-binding domain-containing protein. (135 aa)
A0A1A0H5C8DNA helicase; Belongs to the MCM family. (840 aa)
A0A1A0H5F8Homeobox domain-containing protein. (566 aa)
A0A1A0H5W2P53-like transcription factor. (281 aa)
A0A1A0H5W8Zn(2)-C6 fungal-type domain-containing protein. (607 aa)
A0A1A0H600HSF_DOMAIN domain-containing protein. (611 aa)
A0A1A0H652DNA helicase; Belongs to the MCM family. (840 aa)
A0A1A0H6M2Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (611 aa)
A0A1A0H6S3Histone H2A; Belongs to the histone H2A family. (133 aa)
A0A1A0H6X8DNA-binding TFAR19-related protein. (119 aa)
A0A1A0H6Y2DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (795 aa)
A0A1A0H6Y3Zn(2)-C6 fungal-type domain-containing protein. (757 aa)
A0A1A0H710Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (276 aa)
A0A1A0H712DNA-binding protein. (220 aa)
A0A1A0H775Zn(2)-C6 fungal-type domain-containing protein. (791 aa)
A0A1A0H7U8Glucocorticoid receptor-like (DNA-binding domain). (115 aa)
A0A1A0H7X2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (990 aa)
A0A1A0H829Winged helix DNA-binding domain-containing protein. (236 aa)
A0A1A0H840Zn(2)-C6 fungal-type domain-containing protein. (773 aa)
A0A1A0H863DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2228 aa)
A0A1A0H8X1DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (922 aa)
A0A1A0H953Histone H3; Belongs to the histone H3 family. (136 aa)
A0A1A0H9I1Zn(2)-C6 fungal-type domain-containing protein. (662 aa)
A0A1A0H9Q7DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (624 aa)
A0A1A0H9T5DNA helicase; Belongs to the MCM family. (904 aa)
A0A1A0H9X3SRF-TF-domain-containing protein. (233 aa)
A0A1A0H9Z1Putative telomere binding protein. (135 aa)
A0A1A0HAF4DNA polymerase. (1459 aa)
A0A1A0HAU0HMG box domain-containing protein. (483 aa)
A0A1A0HAY5Response regulator. (464 aa)
A0A1A0HBC9DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (545 aa)
A0A1A0HBF9Zn(2)-C6 fungal-type domain-containing protein. (945 aa)
A0A1A0HBW3Histone H2A; Belongs to the histone H2A family. (130 aa)
A0A1A0HCU1Histone H3; Belongs to the histone H3 family. (136 aa)
A0A1A0HCR0Homeobox domain-containing protein. (217 aa)
A0A1A0HCQ1HSF_DOMAIN domain-containing protein. (761 aa)
A0A1A0HCG0Zn(2)-C6 fungal-type domain-containing protein. (843 aa)
A0A1A0HC99HMG box domain-containing protein. (279 aa)
A0A1A0HC01DNA-binding protein. (203 aa)
A0A1A0H202DNA polymerase. (1067 aa)
A0A1A0HKI3Glucocorticoid receptor-like (DNA-binding domain). (57 aa)
A0A1A0HKD6DNA polymerase. (1580 aa)
A0A1A0HJZ4Zn(2)-C6 fungal-type domain-containing protein. (901 aa)
A0A1A0HJY1DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (515 aa)
A0A1A0HJK9Zn(2)-C6 fungal-type domain-containing protein. (621 aa)
A0A1A0HJ01DNA helicase; Belongs to the MCM family. (727 aa)
A0A1A0HIK2Uncharacterized protein. (848 aa)
A0A1A0HBY7Winged helix DNA-binding domain-containing protein. (262 aa)
A0A1A0HIE3MADS-box domain-containing protein. (446 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (780 aa)
A0A1A0HI73Homeobox-domain-containing protein. (422 aa)
A0A1A0HHK8HMG-box. (271 aa)
A0A1A0HH54Uncharacterized protein. (163 aa)
A0A1A0HGN6Glucocorticoid receptor-like (DNA-binding domain). (78 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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