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A0A1A0HG91 A0A1A0HG91 A0A1A0HFX5 A0A1A0HFX5 A0A1A0HFF8 A0A1A0HFF8 A0A1A0HFE7 A0A1A0HFE7 A0A1A0HF87 A0A1A0HF87 A0A1A0HF55 A0A1A0HF55 A0A1A0HEG4 A0A1A0HEG4 A0A1A0HDS7 A0A1A0HDS7 A0A1A0HDN0 A0A1A0HDN0 A0A1A0HDM7 A0A1A0HDM7 A0A1A0HDM2 A0A1A0HDM2 A0A1A0HDF5 A0A1A0HDF5 UTR4 UTR4 A0A1A0HCW9 A0A1A0HCW9 HAM1 HAM1 A0A1A0HBK6 A0A1A0HBK6 FEN1 FEN1 A0A1A0H992 A0A1A0H992 A0A1A0H8W3 A0A1A0H8W3 A0A1A0H8V7 A0A1A0H8V7 A0A1A0H8V4 A0A1A0H8V4 A0A1A0H8K8 A0A1A0H8K8 A0A1A0H8J4 A0A1A0H8J4 A0A1A0H827 A0A1A0H827 A0A1A0H805 A0A1A0H805 A0A1A0H779 A0A1A0H779 A0A1A0H726 A0A1A0H726 A0A1A0H6N1 A0A1A0H6N1 A0A1A0H6C7 A0A1A0H6C7 A0A1A0H660 A0A1A0H660 A0A1A0H5T1 A0A1A0H5T1 A0A1A0H5H7 A0A1A0H5H7 A0A1A0H5B6 A0A1A0H5B6 A0A1A0H4Y6 A0A1A0H4Y6 RBK1 RBK1 A0A1A0H4I9 A0A1A0H4I9 A0A1A0H257 A0A1A0H257 A0A1A0HGW1 A0A1A0HGW1 A0A1A0HH33 A0A1A0HH33 A0A1A0HH56 A0A1A0HH56 A0A1A0HHD0 A0A1A0HHD0 A0A1A0HHZ7 A0A1A0HHZ7 A0A1A0HI09 A0A1A0HI09 A0A1A0HI97 A0A1A0HI97 A0A1A0HIA6 A0A1A0HIA6 A0A1A0HIY4 A0A1A0HIY4 A0A1A0HGV4 A0A1A0HGV4 A0A1A0HK69 A0A1A0HK69 A0A1A0HKJ9 A0A1A0HKJ9 A0A1A0HKP9 A0A1A0HKP9 A0A1A0HKS0 A0A1A0HKS0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A1A0HG91Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (424 aa)
A0A1A0HFX5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1215 aa)
A0A1A0HFF8Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (896 aa)
A0A1A0HFE7Amidophosphoribosyltransferase. (537 aa)
A0A1A0HF87Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (677 aa)
A0A1A0HF55Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
A0A1A0HEG4PP2C-domain-containing protein. (483 aa)
A0A1A0HDS7Pyruvate decarboxylase. (620 aa)
A0A1A0HDN0Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (561 aa)
A0A1A0HDM7Pyruvate decarboxylase. (617 aa)
A0A1A0HDM2ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (946 aa)
A0A1A0HDF5Isocitrate lyase. (551 aa)
UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (228 aa)
A0A1A0HCW9Magnesium transporter. (389 aa)
HAM1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
A0A1A0HBK6Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (485 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (374 aa)
A0A1A0H992Ketol-acid reductoisomerase; Belongs to the ketol-acid reductoisomerase family. (353 aa)
A0A1A0H8W3Alkaline phosphatase. (490 aa)
A0A1A0H8V7Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (409 aa)
A0A1A0H8V4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1181 aa)
A0A1A0H8K8IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (467 aa)
A0A1A0H8J4Protein serine/threonine phosphatase 2C. (332 aa)
A0A1A0H827Protein phosphatase 2C. (342 aa)
A0A1A0H805Acetolactate synthase. (675 aa)
A0A1A0H779Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1379 aa)
A0A1A0H726Protein serine/threonine phosphatase 2C. (569 aa)
A0A1A0H6N15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)
A0A1A0H6C7Magnesium transporter. (388 aa)
A0A1A0H660Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
A0A1A0H5T1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1641 aa)
A0A1A0H5H7ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (979 aa)
A0A1A0H5B63,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (202 aa)
A0A1A0H4Y6S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (382 aa)
RBK1Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (329 aa)
A0A1A0H4I9Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (532 aa)
A0A1A0H257Protein phosphatase; Belongs to the PP2C family. (401 aa)
A0A1A0HGW1Protein phosphatase; Belongs to the PP2C family. (302 aa)
A0A1A0HH33Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (427 aa)
A0A1A0HH56Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (367 aa)
A0A1A0HHD0Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (376 aa)
A0A1A0HHZ7tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (266 aa)
A0A1A0HI09Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1408 aa)
A0A1A0HI973-oxoacyl-[acyl-carrier-protein] reductase. (1881 aa)
A0A1A0HIA6Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (485 aa)
A0A1A0HIY4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1490 aa)
A0A1A0HGV4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1323 aa)
A0A1A0HK69Pyruvate decarboxylase. (562 aa)
A0A1A0HKJ9Glutathione synthetase. (490 aa)
A0A1A0HKP9Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (509 aa)
A0A1A0HKS0Phosphoglucomutase, first 3 domain-containing protein; Belongs to the phosphohexose mutase family. (553 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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