STRINGSTRING
A0A1A0H6B9 A0A1A0H6B9 A0A1A0H6B6 A0A1A0H6B6 A0A1A0H5P7 A0A1A0H5P7 A0A1A0H5N1 A0A1A0H5N1 A0A1A0H5E4 A0A1A0H5E4 A0A1A0H546 A0A1A0H546 A0A1A0H4S5 A0A1A0H4S5 A0A1A0H256 A0A1A0H256 A0A1A0H216 A0A1A0H216 A0A1A0H1R1 A0A1A0H1R1 A0A1A0H6D0 A0A1A0H6D0 A0A1A0H6F3 A0A1A0H6F3 A0A1A0H6F6 A0A1A0H6F6 A0A1A0H6W5 A0A1A0H6W5 A0A1A0H721 A0A1A0H721 A0A1A0H764 A0A1A0H764 A0A1A0H7N9 A0A1A0H7N9 A0A1A0H7P0 A0A1A0H7P0 A0A1A0H7W5 A0A1A0H7W5 A0A1A0H8S1 A0A1A0H8S1 A0A1A0H908 A0A1A0H908 A0A1A0H912 A0A1A0H912 A0A1A0H950 A0A1A0H950 A0A1A0H9J7 A0A1A0H9J7 AAH1 AAH1 ADK1 ADK1 A0A1A0HAA6 A0A1A0HAA6 A0A1A0HAH0 A0A1A0HAH0 A0A1A0HAR4 A0A1A0HAR4 A0A1A0HAW2 A0A1A0HAW2 A0A1A0HBB5 A0A1A0HBB5 A0A1A0HCC9 A0A1A0HCC9 HAM1 HAM1 A0A1A0HDN4 A0A1A0HDN4 A0A1A0HDT0 A0A1A0HDT0 A0A1A0HF24 A0A1A0HF24 A0A1A0HF85 A0A1A0HF85 A0A1A0HFE7 A0A1A0HFE7 A0A1A0HFL8 A0A1A0HFL8 A0A1A0HG56 A0A1A0HG56 A0A1A0HGF6 A0A1A0HGF6 A0A1A0HGY3 A0A1A0HGY3 A0A1A0HH33 A0A1A0HH33 A0A1A0HHF3 A0A1A0HHF3 URA6 URA6 A0A1A0HIH4 A0A1A0HIH4 A0A1A0HJ32 A0A1A0HJ32 A0A1A0HJQ7 A0A1A0HJQ7 A0A1A0HJU7 A0A1A0HJU7 A0A1A0HK11 A0A1A0HK11 A0A1A0HKM4 A0A1A0HKM4 A0A1A0HL24 A0A1A0HL24 A0A1A0HL58 A0A1A0HL58
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1A0H6B9CMP/dCMP-type deaminase domain-containing protein. (323 aa)
A0A1A0H6B6Amidohydro-rel domain-containing protein. (451 aa)
A0A1A0H5P7Nucleoside diphosphate kinase. (152 aa)
A0A1A0H5N1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)
A0A1A0H5E4Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (240 aa)
A0A1A0H546Glutaredoxin domain-containing protein. (118 aa)
A0A1A0H4S5Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (560 aa)
A0A1A0H256Deoxyuridine 5'-triphosphate nucleotidohydrolase. (153 aa)
A0A1A0H216Carbamoyl-phosphate synth. (2207 aa)
A0A1A0H1R1Phosphoribosylformylglycinamidin. (1349 aa)
A0A1A0H6D0Thioredoxin; Belongs to the thioredoxin family. (103 aa)
A0A1A0H6F3Uncharacterized protein. (1000 aa)
A0A1A0H6F6Putative uracil phosphoribosyltransferase. (215 aa)
A0A1A0H6W5Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (707 aa)
A0A1A0H721HAD-like protein. (242 aa)
A0A1A0H764Orotate phosphoribosyltransferase. (219 aa)
A0A1A0H7N9Phosphoribosylamine--glycine ligase. (793 aa)
A0A1A0H7P0Phosphoribosylglycinamide formyltransferase. (235 aa)
A0A1A0H7W5Uridine kinase; Belongs to the uridine kinase family. (509 aa)
A0A1A0H8S1Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (568 aa)
A0A1A0H908Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (140 aa)
A0A1A0H912Guanylate kinase. (187 aa)
A0A1A0H950Nudix hydrolase domain-containing protein. (206 aa)
A0A1A0H9J7Adenine phosphoribosyltransferase. (185 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (355 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (249 aa)
A0A1A0HAA6P-loop containing nucleoside triphosphate hydrolase protein. (235 aa)
A0A1A0HAH0GMP synthase. (533 aa)
A0A1A0HAR4Thymidylate kinase. (208 aa)
A0A1A0HAW2SAICAR synthetase. (306 aa)
A0A1A0HBB5Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (429 aa)
A0A1A0HCC9Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (900 aa)
HAM1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
A0A1A0HDN4Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (723 aa)
A0A1A0HDT0Uncharacterized protein. (429 aa)
A0A1A0HF24Ribokinase-like protein. (346 aa)
A0A1A0HF85Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (514 aa)
A0A1A0HFE7Amidophosphoribosyltransferase. (537 aa)
A0A1A0HFL8Glutaredoxin domain-containing protein. (211 aa)
A0A1A0HG56Metallo-dependent hydrolase. (487 aa)
A0A1A0HGF6AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (737 aa)
A0A1A0HGY3CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (575 aa)
A0A1A0HH33Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (427 aa)
A0A1A0HHF3HAD-like protein. (253 aa)
URA6Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (218 aa)
A0A1A0HIH4Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (869 aa)
A0A1A0HJ32Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
A0A1A0HJQ7Thioredoxin; Belongs to the thioredoxin family. (138 aa)
A0A1A0HJU7Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (263 aa)
A0A1A0HK11Thymidylate synthase. (315 aa)
A0A1A0HKM4AICARFT/IMPCHase bienzyme. (589 aa)
A0A1A0HL24Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (310 aa)
A0A1A0HL58P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the adenylate kinase family. (166 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.