node1 | node2 | node1 annotation | node2 annotation | score |
A0A1A0H4T9 | A0A1A0H6Y2 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.958 |
A0A1A0H4T9 | A0A1A0H732 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.824 |
A0A1A0H4T9 | A0A1A0HDG9 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Uncharacterized protein. | 0.434 |
A0A1A0H4T9 | A0A1A0HFL1 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.814 |
A0A1A0H4T9 | A0A1A0HGF5 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | Ubiquitin-like protein. | 0.878 |
A0A1A0H4T9 | A0A1A0HID9 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | RanBD1 domain-containing protein. | 0.623 |
A0A1A0H6Y2 | A0A1A0H4T9 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.958 |
A0A1A0H6Y2 | A0A1A0H732 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.840 |
A0A1A0H6Y2 | A0A1A0HFL1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.525 |
A0A1A0H6Y2 | A0A1A0HGF5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-like protein. | 0.846 |
A0A1A0H732 | A0A1A0H4T9 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.824 |
A0A1A0H732 | A0A1A0H6Y2 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.840 |
A0A1A0H732 | A0A1A0H8W9 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | NUP214 domain-containing protein. | 0.704 |
A0A1A0H732 | A0A1A0H9R6 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | C3H1-type domain-containing protein. | 0.667 |
A0A1A0H732 | A0A1A0HDG9 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Uncharacterized protein. | 0.989 |
A0A1A0H732 | A0A1A0HFL1 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.970 |
A0A1A0H732 | A0A1A0HGF5 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-like protein. | 0.999 |
A0A1A0H732 | A0A1A0HGG4 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | PA14 domain-containing protein. | 0.621 |
A0A1A0H732 | A0A1A0HGX2 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | PA14 domain-containing protein. | 0.621 |
A0A1A0H732 | A0A1A0HID9 | Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | RanBD1 domain-containing protein. | 0.998 |