STRINGSTRING
A0A1A0H591 A0A1A0H591 A0A1A0H8S0 A0A1A0H8S0 GET3 GET3 A0A1A0HFV4 A0A1A0HFV4 A0A1A0HFI4 A0A1A0HFI4 A0A1A0H9C3 A0A1A0H9C3 A0A1A0HCQ0 A0A1A0HCQ0 A0A1A0HDJ2 A0A1A0HDJ2 A0A1A0HDW6 A0A1A0HDW6 A0A1A0HE14 A0A1A0HE14 GET1 GET1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A1A0H591Uncharacterized protein. (554 aa)
A0A1A0H8S0Cytochrome b5; Belongs to the cytochrome b5 family. (126 aa)
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (349 aa)
A0A1A0HFV4Protein translocase SEC6. (67 aa)
A0A1A0HFI4Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa)
A0A1A0H9C3t-SNARE; Belongs to the syntaxin family. (314 aa)
A0A1A0HCQ0PapD-like protein. (124 aa)
A0A1A0HDJ2DUF410-domain-containing protein. (317 aa)
A0A1A0HDW6Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (90 aa)
A0A1A0HE14UBC-like protein. (238 aa)
GET1Golgi to ER traffic protein 1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP- dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. (218 aa)
Your Current Organism:
Metschnikowia bicuspidata
NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993
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