(24 nodes) Terpenoid backbone biosynthesis network (Metschnikowia bicuspidata)

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Your Input:
	A0A1A0GZ06	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (457 aa)
	A0A1A0H571	Alkyl transferase; Belongs to the UPP synthase family. (279 aa)
	A0A1A0H5M9	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family. (441 aa)
	A0A1A0H711	C3HC-type domain-containing protein. (476 aa)
	A0A1A0H761	Abi-domain-containing protein. (271 aa)
	A0A1A0H7U3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (447 aa)
	A0A1A0H8G1	Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (343 aa)
	A0A1A0HA41	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (425 aa)
	A0A1A0HAH5	Protein prenylyltransferase. (287 aa)
	A0A1A0HAH6	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (385 aa)
	A0A1A0HBK2	Arnesyl diphosphate synthetase; Belongs to the FPP/GGPP synthase family. (350 aa)
	A0A1A0HCJ2	TPR-like protein. (603 aa)
	A0A1A0HDH9	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (855 aa)
	A0A1A0HDY1	Isopentenyldiphosphate isomerase. (280 aa)
	A0A1A0HE16	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (431 aa)
	A0A1A0HFC0	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (778 aa)
	A0A1A0HG18	Alkyl transferase; Belongs to the UPP synthase family. (320 aa)
	A0A1A0HGN8	Peptidase_M48 domain-containing protein. (321 aa)
	A0A1A0HH89	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (437 aa)
	A0A1A0HHC8	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1014 aa)
	A0A1A0HHR3	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	A0A1A0HIT4	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (213 aa)
	A0A1A0HIY3	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (229 aa)
	A0A1A0HK39	Undecaprenyl diphosphate synthase. (278 aa)

Your Current Organism:

Metschnikowia bicuspidata

NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1A0GZ06	A0A1A0H761	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Abi-domain-containing protein.	0.950
A0A1A0GZ06	A0A1A0HAH5	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein prenylyltransferase.	0.893
A0A1A0GZ06	A0A1A0HGN8	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Peptidase_M48 domain-containing protein.	0.407
A0A1A0GZ06	A0A1A0HH89	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.896
A0A1A0GZ06	A0A1A0HIT4	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	0.725
A0A1A0GZ06	A0A1A0HIY3	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.	0.725
A0A1A0H571	A0A1A0H5M9	Alkyl transferase; Belongs to the UPP synthase family.	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	0.834
A0A1A0H571	A0A1A0H8G1	Alkyl transferase; Belongs to the UPP synthase family.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.830
A0A1A0H571	A0A1A0HAH5	Alkyl transferase; Belongs to the UPP synthase family.	Protein prenylyltransferase.	0.835
A0A1A0H571	A0A1A0HAH6	Alkyl transferase; Belongs to the UPP synthase family.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.571
A0A1A0H571	A0A1A0HBK2	Alkyl transferase; Belongs to the UPP synthase family.	Arnesyl diphosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.883
A0A1A0H571	A0A1A0HDY1	Alkyl transferase; Belongs to the UPP synthase family.	Isopentenyldiphosphate isomerase.	0.724
A0A1A0H571	A0A1A0HG18	Alkyl transferase; Belongs to the UPP synthase family.	Alkyl transferase; Belongs to the UPP synthase family.	0.845
A0A1A0H571	A0A1A0HH89	Alkyl transferase; Belongs to the UPP synthase family.	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	0.835
A0A1A0H571	A0A1A0HK39	Alkyl transferase; Belongs to the UPP synthase family.	Undecaprenyl diphosphate synthase.	0.960
A0A1A0H5M9	A0A1A0H571	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	Alkyl transferase; Belongs to the UPP synthase family.	0.834
A0A1A0H5M9	A0A1A0H7U3	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.545
A0A1A0H5M9	A0A1A0H8G1	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	Terpenoid synthase; Belongs to the FPP/GGPP synthase family.	0.865
A0A1A0H5M9	A0A1A0HAH5	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	Protein prenylyltransferase.	0.832
A0A1A0H5M9	A0A1A0HAH6	Hexaprenyl pyrophosphate synthetase mitochondrial; Belongs to the FPP/GGPP synthase family.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.932