(55 nodes) Phagosome network (Metschnikowia bicuspidata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	A0A1A0H4Q5	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (196 aa)
	A0A1A0H516	DUF654-domain-containing protein. (686 aa)
	A0A1A0H683	FAD-binding FR-type domain-containing protein. (629 aa)
	A0A1A0H6G1	Vacuolar ATP synthase subunit D. (321 aa)
	A0A1A0H6Z0	FAD-binding FR-type domain-containing protein. (694 aa)
	A0A1A0H717	Ras-domain-containing protein. (213 aa)
	A0A1A0H740	Ferric oxidoreductase domain-containing protein. (720 aa)
	A0A1A0H7A1	Uncharacterized protein. (738 aa)
	A0A1A0H7F8	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	A0A1A0H7T3	Mannose 6-phosphate receptor domain-containing protein. (271 aa)
	A0A1A0H7U7	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (318 aa)
	A0A1A0H8E7	Initiation factor 2. (775 aa)
	A0A1A0H8J0	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (509 aa)
	A0A1A0H8L4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (950 aa)
	A0A1A0H8U1	Mitochondrial intermembrane space translocase subunit Tim9. (83 aa)
	A0A1A0H9M3	Ras-domain-containing protein. (325 aa)
	A0A1A0H9Q8	Phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (997 aa)
	A0A1A0HA15	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	A0A1A0HA75	Ferric reductase transmembrane component. (744 aa)
	A0A1A0HA86	FAD-binding FR-type domain-containing protein. (713 aa)
	A0A1A0HAE9	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (160 aa)
	A0A1A0HAF0	WD_REPEATS_REGION domain-containing protein. (597 aa)
	A0A1A0HAF3	Ras-domain-containing protein. (214 aa)
	A0A1A0HAW5	Uncharacterized protein. (684 aa)
	A0A1A0HBQ5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (790 aa)
	A0A1A0HC74	Protein transport protein SEC61 alpha subunit. (478 aa)
	A0A1A0HCT0	Vacuolar ATP synthase subunit E. (226 aa)
	A0A1A0HD44	Uncharacterized protein. (703 aa)
	A0A1A0HDD1	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (160 aa)
	A0A1A0HDD6	FAD-binding FR-type domain-containing protein. (647 aa)
	A0A1A0HDJ1	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa)
	A0A1A0HJE8	Uncharacterized protein. (1078 aa)
	A0A1A0HL45	Uncharacterized protein. (70 aa)
	A0A1A0HDW6	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (90 aa)
	A0A1A0HJI8	DEAD-domain-containing protein; Belongs to the DEAD box helicase family. (480 aa)
	A0A1A0HDX1	Coronin; Belongs to the WD repeat coronin family. (659 aa)
	A0A1A0HDY0	Uncharacterized protein. (735 aa)
	A0A1A0HJV3	Snare-like protein; Belongs to the synaptobrevin family. (215 aa)
	A0A1A0HDZ9	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	A0A1A0HE77	FAD-binding FR-type domain-containing protein. (660 aa)
	A0A1A0HEK4	t-SNARE coiled-coil homology domain-containing protein. (330 aa)
	A0A1A0HEN1	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (477 aa)
	A0A1A0HET1	Ferric reductase. (595 aa)
	A0A1A0HF07	Ras-domain-containing protein. (221 aa)
	A0A1A0HFA0	Uncharacterized protein. (213 aa)
	A0A1A0HFV4	Protein translocase SEC6. (67 aa)
	A0A1A0HG84	Uncharacterized protein. (195 aa)
	A0A1A0HGL1	SecY protein; Belongs to the SecY/SEC61-alpha family. (491 aa)
	A0A1A0HGZ3	DUF1709-domain-containing protein. (1453 aa)
	A0A1A0HH05	Calreticulin-domain-containing protein. (573 aa)
	A0A1A0HHJ0	Uncharacterized protein. (4188 aa)
	A0A1A0HHM8	Presequence translocated-associated motor subunit PAM17, mitochondrial. (149 aa)
	A0A1A0HHZ1	FAD-binding FR-type domain-containing protein. (689 aa)
	A0A1A0HI49	Uncharacterized protein. (515 aa)
	A0A1A0H4K2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (111 aa)

Your Current Organism:

Metschnikowia bicuspidata

NCBI taxonomy Id: 869754
Other names: M. bicuspidata var. bicuspidata NRRL YB-4993, Metschnikowia bicuspidata var. bicuspidata NRRL YB-4993

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1A0H4K2	A0A1A0H4Q5	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.998
A0A1A0H4K2	A0A1A0H6G1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar ATP synthase subunit D.	0.998
A0A1A0H4K2	A0A1A0H7U7	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
A0A1A0H4K2	A0A1A0H8J0	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.998
A0A1A0H4K2	A0A1A0H8L4	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
A0A1A0H4K2	A0A1A0HAE9	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
A0A1A0H4K2	A0A1A0HBQ5	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
A0A1A0H4K2	A0A1A0HCT0	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar ATP synthase subunit E.	0.998
A0A1A0H4K2	A0A1A0HDD1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.972
A0A1A0H4K2	A0A1A0HDJ1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
A0A1A0H4K2	A0A1A0HDZ9	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.	0.998
A0A1A0H4K2	A0A1A0HEN1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.999
A0A1A0H4K2	A0A1A0HF07	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Ras-domain-containing protein.	0.571
A0A1A0H4K2	A0A1A0HJE8	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.997
A0A1A0H4K2	A0A1A0HL45	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.878
A0A1A0H4Q5	A0A1A0H4K2	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
A0A1A0H4Q5	A0A1A0H6G1	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	Vacuolar ATP synthase subunit D.	0.999
A0A1A0H4Q5	A0A1A0H7U7	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
A0A1A0H4Q5	A0A1A0H8J0	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
A0A1A0H4Q5	A0A1A0H8L4	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.998