(25 nodes) Mixed, incl. RNA recognition motif, and Eukaryotic translation initiation factor 4F complex network (Ogataea parapolymorpha)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HPODL_02482	Nonsense-mediated mRNA decay protein 2. (906 aa)
	HPODL_02626	ATP-dependent helicase NAM7. (909 aa)
	HPODL_02837	Uncharacterized protein. (484 aa)
	HPODL_02856	Protein WHI3. (602 aa)
	HPODL_02921	Uncharacterized protein. (339 aa)
	HPODL_03000	Uncharacterized protein. (692 aa)
	HPODL_01350	Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1. (349 aa)
	HPODL_03113	Polyadenylate-binding protein, cytoplasmic and nuclear. (541 aa)
	HPODL_01394	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (211 aa)
	HPODL_01780	Polyadenylate-binding protein 2. (198 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1076 aa)
	HPODL_03838	Uncharacterized protein. (590 aa)
	HPODL_04507	C2H2-type domain-containing protein. (905 aa)
	HPODL_04096	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (629 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (625 aa)
	HPODL_04247	Eukaryotic initiation factor 4F subunit p150. (1016 aa)
	HPODL_03677	ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family. (397 aa)
	HPODL_00788	Eukaryotic translation initiation factor 4B. (386 aa)
	HPODL_00728	RNA-binding protein MRN1. (482 aa)
	HPODL_00204	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family. (518 aa)
	HPODL_04945	ATP-dependent RNA helicase DED1; Belongs to the DEAD box helicase family. (602 aa)
	HPODL_04958	Uncharacterized protein. (954 aa)
	HPODL_02288	Uncharacterized protein. (315 aa)
	HPODL_04984	RNA binding protein. (404 aa)
	HPODL_02017	Uncharacterized protein. (756 aa)

Your Current Organism:

Ogataea parapolymorpha

NCBI taxonomy Id: 871575
Other names: Hansenula polymorpha DL-1, O. parapolymorpha DL-1, Ogataea parapolymorpha ATCC 26012, Ogataea parapolymorpha DL-1, Pichia angusta DL-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HPODL_00204	HPODL_00728	W1QII8	W1QI66	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	RNA-binding protein MRN1.	0.485
HPODL_00204	HPODL_00788	W1QII8	W1QH69	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Eukaryotic translation initiation factor 4B.	0.485
HPODL_00204	HPODL_01350	W1QII8	W1Q8W3	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1.	0.485
HPODL_00204	HPODL_01394	W1QII8	W1Q906	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.767
HPODL_00204	HPODL_01780	W1QII8	W1QA57	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Polyadenylate-binding protein 2.	0.589
HPODL_00204	HPODL_02017	W1QII8	W1QKD9	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.682
HPODL_00204	HPODL_02288	W1QII8	W1QJV3	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.485
HPODL_00204	HPODL_02482	W1QII8	W1Q6T4	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Nonsense-mediated mRNA decay protein 2.	0.585
HPODL_00204	HPODL_02626	W1QII8	W1Q6Y2	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	ATP-dependent helicase NAM7.	0.477
HPODL_00204	HPODL_02837	W1QII8	W1Q788	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.762
HPODL_00204	HPODL_02856	W1QII8	W1Q7A1	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Protein WHI3.	0.485
HPODL_00204	HPODL_03000	W1QII8	W1Q7N2	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.485
HPODL_00204	HPODL_03113	W1QII8	W1Q8Z1	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Polyadenylate-binding protein, cytoplasmic and nuclear.	0.682
HPODL_00204	HPODL_03677	W1QII8	W1QFL3	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family.	0.679
HPODL_00204	HPODL_03838	W1QII8	W1QAZ2	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.714
HPODL_00204	HPODL_04096	W1QII8	W1QD42	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.682
HPODL_00204	HPODL_04247	W1QII8	W1QDG8	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Eukaryotic initiation factor 4F subunit p150.	0.714
HPODL_00204	HPODL_04507	W1QII8	W1QD06	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	C2H2-type domain-containing protein.	0.477
HPODL_00204	HPODL_04958	W1QII8	W1QIS7	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	Uncharacterized protein.	0.485
HPODL_00204	PAN3	W1QII8	W1QDC0	Mitochondrial ATP-dependent RNA helicase of the DEAD-box family.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	0.417

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