STRINGSTRING
HPODL_02895 HPODL_02895 HPODL_03114 HPODL_03114 HPODL_01789 HPODL_01789 HPODL_01775 HPODL_01775 HPODL_03044 HPODL_03044 NBP35 NBP35 HPODL_04156 HPODL_04156 HPODL_03863 HPODL_03863 HPODL_04047 HPODL_04047 HPODL_03334 HPODL_03334 HPODL_04323 HPODL_04323 HPODL_05266 HPODL_05266 HPODL_00218 HPODL_00218 HPODL_00331 HPODL_00331 HPODL_03451 HPODL_03451 HPODL_05145 HPODL_05145 HPODL_00884 HPODL_00884 HPODL_04658 HPODL_04658 HPODL_04734 HPODL_04734 CFD1 CFD1 HPODL_04571 HPODL_04571 HPODL_02010 HPODL_02010 HPODL_04757 HPODL_04757 DRE2 DRE2 HPODL_02128 HPODL_02128 HPODL_04914 HPODL_04914 TAH18 TAH18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HPODL_02895MIP18 family protein. (186 aa)
HPODL_03114Protein involved in iron metabolism in mitochondria. (242 aa)
HPODL_01789Uncharacterized protein; Belongs to the BolA/IbaG family. (99 aa)
HPODL_01775Iron-sulfur clusters transporter ATM1, mitochondrial. (693 aa)
HPODL_03044Uncharacterized protein. (271 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NB [...] (324 aa)
HPODL_04156DNA repair/transcription protein MET18/MMS19. (1027 aa)
HPODL_03863Cytosolic Fe-S cluster assembly factor NAR1; Belongs to the NARF family. (507 aa)
HPODL_04047Monothiol glutaredoxin-4. (255 aa)
HPODL_03334Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria. (198 aa)
HPODL_04323Cytosolic iron-sulfur protein assembly protein 1. (276 aa)
HPODL_05266Uncharacterized protein; Belongs to the BolA/IbaG family. (88 aa)
HPODL_00218Fe-S_biosyn domain-containing protein. (197 aa)
HPODL_00331Yae1_N domain-containing protein. (167 aa)
HPODL_03451Uncharacterized protein. (109 aa)
HPODL_05145Uncharacterized protein; Belongs to the BolA/IbaG family. (104 aa)
HPODL_00884Uncharacterized protein. (239 aa)
HPODL_04658Uncharacterized protein. (376 aa)
HPODL_04734Protein involved in iron metabolism in mitochondria. (250 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD [...] (267 aa)
HPODL_04571Mitochondrial Fe-S cluster biosynthesis protein ISA2 (Contains a HesB-like domain). (171 aa)
HPODL_02010Yae1_N domain-containing protein. (147 aa)
HPODL_04757Aminotran_5 domain-containing protein. (398 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (347 aa)
HPODL_02128Cysteine desulfurase, mitochondrial. (457 aa)
HPODL_04914Iron-sulfur protein IND1. (261 aa)
TAH18NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (589 aa)
Your Current Organism:
Ogataea parapolymorpha
NCBI taxonomy Id: 871575
Other names: Hansenula polymorpha DL-1, O. parapolymorpha DL-1, Ogataea parapolymorpha ATCC 26012, Ogataea parapolymorpha DL-1, Pichia angusta DL-1
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