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| | yafC-3 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (370 aa) |
| | nrdA | Ribonucleoside diphosphate reductase, alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (944 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (189 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (244 aa) |
| | prs | Ribose-phosphate pyrophosphokinase (phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (622 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (135 aa) |
| | yeaT | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (326 aa) |
| | nadE2 | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (541 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (150 aa) |
| | algC | Phosphomannomutase. (472 aa) |
| | fecI | Sigma-24 (FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (173 aa) |
| | nadX | L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (263 aa) |
| | gcvA | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (287 aa) |
| | ADY80881.1 | Hypothetical protein. (152 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (220 aa) |
| | dnaQ | Bifunctional protein dnaQ; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (459 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa) |
| | ttdR | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (306 aa) |
| | add | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (332 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (439 aa) |
| | crp | cAMP-regulatory protein. (235 aa) |
| | ADY81025.1 | Competence damage-inducible protein A; Belongs to the CinA family. (164 aa) |
| | pyrB | Aspartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (338 aa) |
| | pyrX | Aspartate carbamoyltransferase, non-catalytic chain (dihydroorotase-like protein). (414 aa) |
| | yhjC | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (299 aa) |
| | fecI-2 | RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa) |
| | ADY81181.1 | RNA polymerase sigma-70 factor, ECF subfamily. (206 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (219 aa) |
| | paaX | Transcriptional regulator, PaaX family. (321 aa) |
| | ADY81298.1 | Putative LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | yafC | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (301 aa) |
| | ADY81350.1 | Competence-damage inducible protein; Belongs to the CinA family. (158 aa) |
| | ltrA | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (311 aa) |
| | yhjC-2 | Putative LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | mdcD | Malonate decarboxylase, beta subunit. (283 aa) |
| | dnaE | DNA polymerase III, alpha chain. (1187 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (405 aa) |
| | queG | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (356 aa) |
| | ADY81502.1 | Hypothetical protein. (155 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (253 aa) |
| | holB | DNA polymerase III, delta prime subunit. (326 aa) |
| | ADY81542.1 | 6-pyruvoyl-tetrahydropterin synthase-like protein. (198 aa) |
| | cmk | Cytidylate kinase (cytidine monophosphate (CMP) kinase). (226 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase (OMP decarboxylase); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (232 aa) |
| | cyaA | Putative adenylate or guanylate cyclase. (488 aa) |
| | y4mQ | Putative LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (283 aa) |
| | ADY81634.1 | Hypothetical protein. (54 aa) |
| | acoA | Acetoin:2,6-dichlorophenolindophenol oxidoreductase alpha subunit. (320 aa) |
| | ADY81827.1 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (497 aa) |
| | prs-2 | Putative ribose-phosphate pyrophosphokinase (phosphoribosyl pyrophosphate synthetase). (294 aa) |
| | ADY81838.1 | Hypothetical protein. (323 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | kynU | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) |
| | impB | DNA-directed DNA polymerase. (441 aa) |
| | accC | Biotin carboxylase (A subunit of acetyl-CoA carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) |
| | dnaX | DNA polymerase III, tau and gamma subunits (DNA elongation factor III); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (685 aa) |
| | yhjC-3 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (202 aa) |
| | dnaB | Replicative DNA helicase;chromosome replication, chain elongation; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (481 aa) |
| | purH | Bifunctional protein purH. (545 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (428 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (513 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (334 aa) |
| | rpoH | RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (276 aa) |
| | ppnK | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (269 aa) |
| | yhjC-4 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (343 aa) |
| | queF | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (270 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (462 aa) |
| | nadB | L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate. (547 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (199 aa) |
| | queE | Queuosine biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (236 aa) |
| | queC | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1274 aa) |
| | ADY82620.1 | RNA polymerase factor sigma-70; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase. (92 aa) |
| | purM2 | Phosphoribosylaminoimidazole synthetase. (207 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (209 aa) |
| | ycaN-2 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (300 aa) |
| | folD | Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa) |
| | carA | Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. (394 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1076 aa) |
| | sucD | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (296 aa) |
| | rpoD | Sigma D (sigma 70) factor of RNA polymerase, major sigma factor during exponential growth; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (636 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa) |
| | ADY82780.1 | Hypothetical protein. (479 aa) |
| | ADY82781.1 | Hypothetical protein. (223 aa) |
| | ADY82807.1 | Hypothetical protein. (266 aa) |
| | ADY82904.1 | Putative acetyl transferase. (139 aa) |
| | accD | acetylCoA carboxylase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queuosine biosynthesis protein); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (345 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (377 aa) |
| | dfp | Bifunctional protein dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (417 aa) |
| | yafC-2 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (302 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (373 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, mutase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (171 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa) |
| | dnaN | DNA polymerase III, beta chain. (138 aa) |
| | dnaN-2 | DNA polymerase III, beta chain. (233 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (191 aa) |
| | rpoA | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (335 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa) |
| | rpoZ | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (92 aa) |
| | acsA | acetyl-CoA synthetase. (66 aa) |
| | acsA2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (571 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | aceF | Dihydrolipoamide S-acetyltransferase, E2 component of the pyruvate dehydrogenase complex. (662 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (216 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (357 aa) |
| | nusB | Transcription termination, L factor (N utilization substance protein B); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (149 aa) |
| | glmU | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (239 aa) |
| | ribF | Bifunctional protein ribF; Belongs to the ribF family. (333 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase); Belongs to the NadC/ModD family. (281 aa) |
| | ADY83558.1 | Hypothetical protein. (316 aa) |
| | wbpD | Acetyltransferase. (192 aa) |
| | manB | Putative bifunctional protein. (456 aa) |
| | acsA-2 | Putative acetyl-coA synthetase/AMP-(fatty) acid ligase. (392 aa) |
| | acsM4 | Putative acetyl-coA synthetase/AMP-(fatty) acid ligase. (151 aa) |
| | bolA | Putative activator of morphogenic pathway (BolA), important in general stress response; Belongs to the BolA/IbaG family. (102 aa) |
| | guaA-2 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. (522 aa) |
| | atpB | Membrane-bound ATP synthase, F0 sector, subunit a, important for FO assembly; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (291 aa) |
| | atpE | Membrane-bound ATP synthase, F0 sector, subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (81 aa) |
| | atpF | Membrane-bound ATP synthase, F0 sector, subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa) |
| | atpH | Membrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa) |
| | atpA | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (514 aa) |
| | atpG | Membrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa) |
| | atpD | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (464 aa) |
| | atpC | Membrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | dinP | DNA polymerase IV, devoid of proofreading, damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa) |
| | holC | DNA polymerase III, chi subunit. (135 aa) |
| | ADY83749.1 | Hypothetical protein. (353 aa) |
| | nusG | Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. (177 aa) |
| | rpoB | RNA polymerase subunit B. (485 aa) |
| | rpoB-2 | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (842 aa) |
| | rpoC | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1391 aa) |
| | ADY83816.1 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (184 aa) |
| | coaE | Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa) |
| | nusA | nusA; Participates in both transcription termination and antitermination. (494 aa) |
| | ADY83839.1 | Hypothetical protein. (201 aa) |
| | ADY83840.1 | Hypothetical protein. (220 aa) |
| | priA | Primosomal protein, ATP-dependent; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (742 aa) |
| | corC | Magnesium and cobalt efflux protein. (269 aa) |
| | yhjC-6 | Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (298 aa) |
| | purU1 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (296 aa) |
| | thyA | thyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (280 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | ackA | Acetate kinase (propionate kinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | ndk | Nucleoside diphosphate kinase (NDK); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) |
| | ADY83999.1 | Hypothetical protein. (263 aa) |
| | holA | Putative DNA polymerase III, delta subunit. (329 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (422 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (273 aa) |
| | polA | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (923 aa) |
| | rpoN | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (491 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (354 aa) |
| | add-2 | Adenosine deaminase. (325 aa) |
| | gcvA-2 | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (315 aa) |
| | gcvA-3 | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (275 aa) |
