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prs prs ADY80638.1 ADY80638.1 ADY84130.1 ADY84130.1 bag bag rpoN rpoN holA holA rpoC rpoC rpoB-2 rpoB-2 rpoB rpoB ADY83749.1 ADY83749.1 holC holC dinP dinP rpoZ rpoZ rpoA rpoA dnaN-2 dnaN-2 dnaN dnaN radC radC ADY82774.1 ADY82774.1 rpoD rpoD ADY82622.1 ADY82622.1 ADY82620.1 ADY82620.1 dgt dgt ADY82601.1 ADY82601.1 thiS thiS rpoH rpoH dnaX dnaX impB impB nasF nasF ADY82073.1 ADY82073.1 ADY81962.1 ADY81962.1 prs-2 prs-2 ADY81743.1 ADY81743.1 appC appC holB holB dnaE dnaE dnaQ dnaQ cysNC cysNC cysD cysD ppk ppk nadE2 nadE2 dnaG dnaG
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prsRibose-phosphate pyrophosphokinase (phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
ADY80638.1Hypothetical protein. (203 aa)
ADY84130.1Hypothetical protein. (219 aa)
bagPutative DNA-directed RNA polymerase II largest subunit. (146 aa)
rpoNRNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (491 aa)
holAPutative DNA polymerase III, delta subunit. (329 aa)
rpoCDNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1391 aa)
rpoB-2DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (842 aa)
rpoBRNA polymerase subunit B. (485 aa)
ADY83749.1Hypothetical protein. (353 aa)
holCDNA polymerase III, chi subunit. (135 aa)
dinPDNA polymerase IV, devoid of proofreading, damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa)
rpoZRNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (92 aa)
rpoARNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (335 aa)
dnaN-2DNA polymerase III, beta chain. (233 aa)
dnaNDNA polymerase III, beta chain. (138 aa)
radCDNA repair protein, associated with replication forks; Belongs to the UPF0758 family. (239 aa)
ADY82774.1Hypothetical protein; Belongs to the UPF0145 family. (116 aa)
rpoDSigma D (sigma 70) factor of RNA polymerase, major sigma factor during exponential growth; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (636 aa)
ADY82622.1Hypothetical protein. (129 aa)
ADY82620.1RNA polymerase factor sigma-70; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase (dGTPase). (446 aa)
ADY82601.1Putative nicotinamide/nicotinate-nucleotide adenylyltransferase. (191 aa)
thiSPart of ThiF/ThiS complex. (65 aa)
rpoHRNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (276 aa)
dnaXDNA polymerase III, tau and gamma subunits (DNA elongation factor III); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (685 aa)
impBDNA-directed DNA polymerase. (441 aa)
nasFPutative nitrate transport protein (NasF). (340 aa)
ADY82073.1Hypothetical protein. (84 aa)
ADY81962.1Hypothetical protein. (225 aa)
prs-2Putative ribose-phosphate pyrophosphokinase (phosphoribosyl pyrophosphate synthetase). (294 aa)
ADY81743.1Putative dipeptide transport protein (ABC superfamily, membrane). (282 aa)
appCProbable ABC transporter, permease protein. (380 aa)
holBDNA polymerase III, delta prime subunit. (326 aa)
dnaEDNA polymerase III, alpha chain. (1187 aa)
dnaQBifunctional protein dnaQ; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (459 aa)
cysNCATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (537 aa)
cysDSulfate adenylyltransferase subunit 2. (302 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (692 aa)
nadE2Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (541 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (622 aa)
Your Current Organism:
Acinetobacter pittii
NCBI taxonomy Id: 871585
Other names: A. pittii PHEA-2, Acinetobacter calcoaceticus PHEA-2, Acinetobacter calcoaceticus str. PHEA-2, Acinetobacter calcoaceticus strain PHEA-2, Acinetobacter pittii PHEA-2
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