STRINGSTRING
AEF34067.1 AEF34067.1 AEF34095.1 AEF34095.1 pckA pckA AEF34194.1 AEF34194.1 fadA2 fadA2 AEF34444.1 AEF34444.1 lpd lpd fadA fadA AEF34899.1 AEF34899.1 fadA3 fadA3 fumC fumC aldA_2 aldA_2 mdh mdh mez_1 mez_1 fadA4 fadA4 accA1 accA1 pdhA pdhA pdhB pdhB pdhC pdhC porA porA porB porB accD6 accD6 aceE aceE mez mez glcB glcB AEF35955.1 AEF35955.1 lldD2 lldD2 pykA pykA AEF36368.1 AEF36368.1 mqo mqo lldD1_1 lldD1_1 AEF36650.1 AEF36650.1 pca pca ilvB1_2 ilvB1_2 AEF36934.1 AEF36934.1 ackA ackA pta pta accA3 accA3 ilvB1_2-2 ilvB1_2-2 lldD1 lldD1 aldA_2-2 aldA_2-2 ltp1_1-2 ltp1_1-2 AEF37409.1 AEF37409.1 aldA aldA ltp1-2 ltp1-2 aldA-2 aldA-2 AEF37519.1 AEF37519.1 aldA-3 aldA-3 ltp3 ltp3 mhpF_1 mhpF_1 fadA5 fadA5 fadA6_1 fadA6_1 aldA-4 aldA-4 ppdK ppdK AEF37806.1 AEF37806.1 ppdK-2 ppdK-2 acs acs leuA leuA AEF38261.1 AEF38261.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEF34067.1Glyoxalase/bleomycin resistance protein/dioxygenase. (117 aa)
AEF34095.1Aldehyde dehydrogenase (NAD+) dependent; Belongs to the aldehyde dehydrogenase family. (458 aa)
pckAIron-regulated phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (606 aa)
AEF34194.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
fadA2acetyl-CoA acetyltransferase FadA2; Belongs to the thiolase-like superfamily. Thiolase family. (448 aa)
AEF34444.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
lpdDihydrolipoamide dehydrogenase Lpd. (466 aa)
fadAacyl-CoA thiolase FadA; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AEF34899.1Thiolase. (511 aa)
fadA3Beta-ketoacyl CoA thiolase FadA3; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
fumCFumarase Fum; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
aldA_2Aldehyde dehydrogenase NAD dependent AldA_2; Belongs to the aldehyde dehydrogenase family. (510 aa)
mdhMalate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
mez_1(NAD) dependent malate oxidoreductase Mez_1. (387 aa)
fadA4acetyl-CoA acetyltransferase FadA4; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
accA1Acetyl-/propionyl-coenzyme A carboxylase alpha chain AccA1. (660 aa)
pdhAPyruvate dehydrogenase E1 component (alpha subunit) PdhA. (364 aa)
pdhBPyruvate dehydrogenase E1 component (beta subunit) PdhB. (349 aa)
pdhCDihydrolipoamide S-acetyltransferase E2 component PdhC. (400 aa)
porAPyruvate:ferredoxin oxidoreductase PorA alpha subunit. (616 aa)
porBPyruvate:ferredoxin oxidoreductase PorB beta subunit. (361 aa)
accD6acetyl/propionyl-CoA carboxylase (beta subunit) AccD6. (473 aa)
aceEPyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa)
mez(NAD) dependent malate oxidoreductase Mez. (547 aa)
glcBMalate synthase G GlcB; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (748 aa)
AEF35955.1acetyl-CoA acetyltransferase. (484 aa)
lldD2L-lactate dehydrogenase (cytochrome) LldD2. (415 aa)
pykAPyruvate kinase PykA; Belongs to the pyruvate kinase family. (472 aa)
AEF36368.1Zn-dependent glyoxylase. (227 aa)
mqoMalate:quinone oxidoreductase Mqo. (476 aa)
lldD1_1L-lactate dehydrogenase (cytochrome) LldD1_1. (386 aa)
AEF36650.1Acylphosphatase. (75 aa)
pcaPyruvate carboxylase Pca; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa)
ilvB1_2Acetolactate synthase (large subunit) IlvB1_2; Belongs to the TPP enzyme family. (578 aa)
AEF36934.1Putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit. (77 aa)
ackAAcetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (381 aa)
ptaPhosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (700 aa)
accA3Bifunctional protein acetyl-/propionyl-coenzyme A carboxylase alpha chain AccA3. (599 aa)
ilvB1_2-2Acetolactate synthase (large subunit) IlvB1_2; Belongs to the TPP enzyme family. (605 aa)
lldD1L-lactate dehydrogenase (cytochrome) LldD1. (397 aa)
aldA_2-2Aldehyde dehydrogenase NAD dependent AldA_2; Belongs to the aldehyde dehydrogenase family. (507 aa)
ltp1_1-2Lipid-transfer protein Ltp1_1; Belongs to the thiolase-like superfamily. Thiolase family. (381 aa)
AEF37409.1Beta-ketoacyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
aldANAD-dependent aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family. (485 aa)
ltp1-2Lipid-transfer protein Ltp1; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
aldA-2NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (504 aa)
AEF37519.1Aldehyde dehydrogenase. (476 aa)
aldA-3NAD-dependent aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family. (489 aa)
ltp3Lipid carrier protein or keto acyl-CoA thiolase Ltp3. (394 aa)
mhpF_1Acetaldehyde dehydrogenase MhpF_1; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (309 aa)
fadA5acetyl-CoA acetyltransferase FadA5; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
fadA6_1acetyl-CoA acetyltransferase FadA6_1; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
aldA-4NAD-dependent aldehyde dehydrogenase AldA; Belongs to the aldehyde dehydrogenase family. (377 aa)
ppdKPyruvate phosphate dikinase PpdK. (534 aa)
AEF37806.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
ppdK-2Pyruvate phosphate dikinase PpdK. (432 aa)
acsAcetyl-coenzyme A synthetase Acs; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa)
leuA2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (604 aa)
AEF38261.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (473 aa)
Your Current Organism:
Mycolicibacter sinensis
NCBI taxonomy Id: 875328
Other names: M. sinensis, Mycobacterium sinense, Mycobacterium sinov, Mycobacterium sp. 506, Mycobacterium sp. JDM601, strain JDM601
Server load: low (12%) [HD]