STRINGSTRING
ADZ08632.1 ADZ08632.1 ADZ08647.1 ADZ08647.1 ADZ08737.1 ADZ08737.1 ADZ08738.1 ADZ08738.1 ADZ08739.1 ADZ08739.1 ADZ08740.1 ADZ08740.1 ADZ08741.1 ADZ08741.1 ADZ08742.1 ADZ08742.1 ADZ08818.1 ADZ08818.1 ADZ09693.1 ADZ09693.1 ADZ09694.1 ADZ09694.1 ADZ09877.1 ADZ09877.1 ADZ09939.1 ADZ09939.1 ADZ10102.1 ADZ10102.1 ADZ10118.1 ADZ10118.1 ADZ10255.1 ADZ10255.1 ADZ10619.1 ADZ10619.1 ADZ10620.1 ADZ10620.1 ADZ10621.1 ADZ10621.1 ADZ10622.1 ADZ10622.1 ADZ10663.1 ADZ10663.1 ADZ10664.1 ADZ10664.1 ADZ10665.1 ADZ10665.1 ADZ10666.1 ADZ10666.1 ADZ10667.1 ADZ10667.1 ADZ10668.1 ADZ10668.1 ADZ10669.1 ADZ10669.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ08632.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (765 aa)
ADZ08647.1TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmg:MTBMA_c14900 pyruvate carboxylase, subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment. (570 aa)
ADZ08737.1PFAM: 4Fe-4S binding domain; KEGG: mth:MTH1736 formate hydrogenlyase, iron-sulfur subunit 2. (143 aa)
ADZ08738.1PFAM: 4Fe-4S binding domain; KEGG: mmg:MTBMA_c03120 HycB-related protein. (166 aa)
ADZ08739.1KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ08740.1KEGG: mmg:MTBMA_c03140 pyruvate synthase, subunit A; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (382 aa)
ADZ08741.1KEGG: mmg:MTBMA_c03150 pyruvate synthase, subunit D; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S binding domain. (80 aa)
ADZ08742.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mth:MTH1740 pyruvate ferredoxin oxidoreductase subunit gamma/delta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (177 aa)
ADZ08818.1TIGRFAM: Acetate-CoA ligase; KEGG: mmg:MTBMA_c01900 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase. (649 aa)
ADZ09693.1KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (573 aa)
ADZ09694.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ09877.1CoA-binding domain protein; KEGG: mbu:Mbur_1347 acyl-CoA synthetase; PFAM: CoA-binding; SMART: CoA-binding. (695 aa)
ADZ09939.1acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase; manually curated; KEGG: mth:MTH217 acetyl-CoA synthetase; TIGRFAM: Acetate-CoA ligase. (634 aa)
ADZ10102.1PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: mru:mru_0603 N-carbamoyl-D-amino acid amidohydrolase AguB. (280 aa)
ADZ10118.1TIGRFAM: Acetate-CoA ligase; KEGG: mfv:Mfer_0074 acetyl-coenzyme a synthetase; PFAM: AMP-dependent synthetase/ligase. (633 aa)
ADZ10255.1Acetolactate synthase; KEGG: mth:MTH476 pyruvate dehydrogenase / acetolactate synthase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Rubredoxin-type Fe(Cys)4 protein; Thiamine pyrophosphate enzyme, central domain. (585 aa)
ADZ10619.1KEGG: mru:mru_1826 2-oxoglutarate ferredoxin oxidoreductase subunit gamma KorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (182 aa)
ADZ10620.1KEGG: mth:MTH1034 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ10621.1KEGG: mmg:MTBMA_c14150 2-oxoglutarate synthase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal. (375 aa)
ADZ10622.1PFAM: 4Fe-4S binding domain; KEGG: mfv:Mfer_0036 2-oxoglutarate ferredoxin oxidoreductase, delta subunit. (69 aa)
ADZ10663.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: mmg:MTBMA_c09240 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (286 aa)
ADZ10664.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (571 aa)
ADZ10665.1PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: mmp:MMP1271 2-oxoisovalerate oxidoreductase subunit alpha. (481 aa)
ADZ10666.13-methyl-2-oxobutanoate dehydrogenase (ferredoxin); KEGG: mmp:MMP1272 2-ketoisovalerate ferredoxin reductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (351 aa)
ADZ10667.1PFAM: 4Fe-4S binding domain; KEGG: mmq:MmarC5_0318 ketoisovalerate ferredoxin oxidoreductase, delta subunit. (102 aa)
ADZ10668.1Butyrate--CoA ligase; KEGG: mba:Mbar_A2172 AMP-binding protein; PFAM: AMP-dependent synthetase/ligase. (557 aa)
ADZ10669.1KEGG: mmz:MmarC7_0521 cupin 2 domain-containing protein; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3. (184 aa)
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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