STRINGSTRING
ADZ08290.1 ADZ08290.1 ADZ08307.1 ADZ08307.1 mtd mtd ADZ08348.1 ADZ08348.1 ADZ08394.1 ADZ08394.1 ADZ08395.1 ADZ08395.1 ADZ08396.1 ADZ08396.1 ADZ08397.1 ADZ08397.1 ADZ08413.1 ADZ08413.1 ADZ08416.1 ADZ08416.1 ADZ08470.1 ADZ08470.1 ADZ08471.1 ADZ08471.1 ADZ08472.1 ADZ08472.1 ADZ08473.1 ADZ08473.1 ADZ08484.1 ADZ08484.1 ftr ftr ADZ08551.1 ADZ08551.1 ADZ08570.1 ADZ08570.1 ADZ08571.1 ADZ08571.1 ADZ08572.1 ADZ08572.1 comB comB ADZ08600.1 ADZ08600.1 ADZ08601.1 ADZ08601.1 ADZ08602.1 ADZ08602.1 ADZ08603.1 ADZ08603.1 ADZ08604.1 ADZ08604.1 ADZ08605.1 ADZ08605.1 mtrE mtrE mtrD mtrD mtrC mtrC mtrB mtrB mtrA mtrA mtrF mtrF mtrG mtrG mtrH mtrH ADZ08614.1 ADZ08614.1 ADZ08615.1 ADZ08615.1 ADZ08616.1 ADZ08616.1 ADZ08617.1 ADZ08617.1 ADZ08620.1 ADZ08620.1 ADZ08621.1 ADZ08621.1 ADZ08622.1 ADZ08622.1 ADZ08623.1 ADZ08623.1 ADZ08624.1 ADZ08624.1 ADZ08628.1 ADZ08628.1 ADZ08629.1 ADZ08629.1 ADZ08630.1 ADZ08630.1 ADZ08641.1 ADZ08641.1 ADZ08657.1 ADZ08657.1 ADZ08659.1 ADZ08659.1 ADZ08696.1 ADZ08696.1 cdhA cdhA cdhB cdhB cdhC cdhC ADZ08717.1 ADZ08717.1 cdhD cdhD cdhE cdhE ADZ08720.1 ADZ08720.1 ADZ08743.1 ADZ08743.1 ADZ08760.1 ADZ08760.1 ADZ08761.1 ADZ08761.1 mer mer ADZ08825.1 ADZ08825.1 ADZ08874.1 ADZ08874.1 ADZ08885.1 ADZ08885.1 ADZ08890.1 ADZ08890.1 ADZ08891.1 ADZ08891.1 ADZ08933.1 ADZ08933.1 ADZ08934.1 ADZ08934.1 ADZ08935.1 ADZ08935.1 ADZ08936.1 ADZ08936.1 ADZ08937.1 ADZ08937.1 ADZ08938.1 ADZ08938.1 ADZ08939.1 ADZ08939.1 ADZ08940.1 ADZ08940.1 ADZ08941.1 ADZ08941.1 ADZ08950.1 ADZ08950.1 ADZ08951.1 ADZ08951.1 ADZ08952.1 ADZ08952.1 ADZ09010.1 ADZ09010.1 ADZ09085.1 ADZ09085.1 ADZ09087.1 ADZ09087.1 ADZ09088.1 ADZ09088.1 ADZ09113.1 ADZ09113.1 ADZ09186.1 ADZ09186.1 mfnB mfnB ADZ09242.1 ADZ09242.1 ADZ09243.1 ADZ09243.1 ADZ09244.1 ADZ09244.1 ADZ09245.1 ADZ09245.1 ADZ09327.1 ADZ09327.1 ADZ09448.1 ADZ09448.1 ADZ09449.1 ADZ09449.1 ADZ09450.1 ADZ09450.1 ADZ09491.1 ADZ09491.1 ADZ09492.1 ADZ09492.1 ADZ09514.1 ADZ09514.1 ADZ09532.1 ADZ09532.1 ADZ09608.1 ADZ09608.1 ADZ09677.1 ADZ09677.1 ADZ09698.1 ADZ09698.1 ADZ10160.1 ADZ10160.1 ADZ10161.1 ADZ10161.1 pcm pcm ADZ10163.1 ADZ10163.1 ADZ10165.1 ADZ10165.1 ADZ10166.1 ADZ10166.1 ADZ10168.1 ADZ10168.1 ADZ10169.1 ADZ10169.1 ADZ10269.1 ADZ10269.1 ADZ10288.1 ADZ10288.1 ADZ10323.1 ADZ10323.1 ADZ10340.1 ADZ10340.1 ADZ10348.1 ADZ10348.1 ADZ10365.1 ADZ10365.1 ADZ10383.1 ADZ10383.1 ADZ10392.1 ADZ10392.1 mch mch ADZ10415.1 ADZ10415.1 hypA hypA ADZ10424.1 ADZ10424.1 ADZ10425.1 ADZ10425.1 ADZ10426.1 ADZ10426.1 ADZ10449.1 ADZ10449.1 ADZ10454.1 ADZ10454.1 ADZ10455.1 ADZ10455.1 ADZ10456.1 ADZ10456.1 ADZ10457.1 ADZ10457.1 ADZ10458.1 ADZ10458.1 ADZ10477.1 ADZ10477.1 ADZ10492.1 ADZ10492.1 ADZ10493.1 ADZ10493.1 ADZ10494.1 ADZ10494.1 ADZ10495.1 ADZ10495.1 ADZ10535.1 ADZ10535.1 ADZ10556.1 ADZ10556.1 ADZ10565.1 ADZ10565.1 ADZ10566.1 ADZ10566.1 ADZ10567.1 ADZ10567.1 ADZ10651.1 ADZ10651.1 ADZ10652.1 ADZ10652.1 ADZ10653.1 ADZ10653.1 ADZ10656.1 ADZ10656.1 ADZ10657.1 ADZ10657.1 ADZ10672.1 ADZ10672.1 ADZ10682.1 ADZ10682.1 ADZ10690.1 ADZ10690.1 ADZ10691.1 ADZ10691.1 ADZ10692.1 ADZ10692.1 ADZ10698.1 ADZ10698.1 ADZ10714.1 ADZ10714.1 ADZ10715.1 ADZ10715.1 ADZ10718.1 ADZ10718.1 ADZ10719.1 ADZ10719.1 ADZ10720.1 ADZ10720.1 ADZ10721.1 ADZ10721.1 ADZ10722.1 ADZ10722.1 ADZ10723.1 ADZ10723.1 ADZ10724.1 ADZ10724.1 ADZ10725.1 ADZ10725.1 ADZ10726.1 ADZ10726.1 ADZ10727.1 ADZ10727.1 ADZ10728.1 ADZ10728.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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from curated databases
experimentally determined
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ADZ08290.1Methanogenesis marker 13 metalloprotein; KEGG: msi:Msm_1160 nitrogenase molybdenum-iron protein, NifD; TIGRFAM: Putative methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase/oxidoreductase, component 1. (359 aa)
ADZ08307.1PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mmg:MTBMA_c00760 ATPase. (262 aa)
mtdF420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa)
ADZ08348.1UPF0285 protein; KEGG: mmg:MTBMA_c00280 putative carbohydrate kinase of the FGGY family; TIGRFAM: Uncharacterised protein family UPF0285, methanogenesis; HAMAP: Uncharacterised protein family UPF0285, methanogenesis; Belongs to the UPF0285 family. (333 aa)
ADZ08394.1PFAM: Protein of unknown function DUF166; KEGG: mth:MTH1356 hypothetical protein. (217 aa)
ADZ08395.1DsrE family protein; PFAM: Sulphur relay, DsrE/F-like protein; KEGG: mth:MTH1358 hypothetical protein. (120 aa)
ADZ08396.1PFAM: Putative Fe-S cluster; KEGG: mmg:MTBMA_c17490 hypothetical protein. (201 aa)
ADZ08397.1DsrH family protein; PFAM: Sulphur relay, TusB/DsrH; KEGG: mmg:MTBMA_c17500 hypothetical protein. (109 aa)
ADZ08413.1Archaeoflavoprotein, MJ0208 family; KEGG: mmg:MTBMA_c17660 conserved hypothetical protein containing a ferredoxin domain; TIGRFAM: Archaeoflavoprotein MJ0208; PFAM: Flavoprotein; 4Fe-4S binding domain. (230 aa)
ADZ08416.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (658 aa)
ADZ08470.1TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; KEGG: mth:MTH1300 coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (405 aa)
ADZ08471.1KEGG: mmg:MTBMA_c16850 F420-reducing hydrogenase, subunit delta; TIGRFAM: Peptidase A31, coenzyme F420-reducing hydrogenase delta subunit; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. (156 aa)
ADZ08472.1TIGRFAM: Coenzyme F420 hydrogenase, subunit gamma; KEGG: mmg:MTBMA_c16840 F420-reducing hydrogenase, subunit gamma; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; 4Fe-4S binding domain. (261 aa)
ADZ08473.1TIGRFAM: Coenzyme F420 hydrogenase, subunit beta; KEGG: mmg:MTBMA_c16830 F420-reducing hydrogenase, subunit beta; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal. (294 aa)
ADZ08484.1Acylphosphatase; TIGRFAM: Carbamoyltransferase, HypF-type; HAMAP: Acylphosphatase; KEGG: mmg:MTBMA_c16720 hydrogenase maturation factor HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type. (768 aa)
ftrFormylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (297 aa)
ADZ08551.1Y414 protein; KEGG: mfv:Mfer_0241 ATP dependent DNA ligase; TIGRFAM: Uncharacterised protein family MJ0414; PFAM: DNA ligase, ATP-dependent, central. (404 aa)
ADZ08570.1TIGRFAM: Sulfopyruvate decarboxylase, beta subunit; KEGG: mmg:MTBMA_c15850 sulfopyruvate decarboxylase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (182 aa)
ADZ08571.1KEGG: msi:Msm_0080 sulfopyruvate decarboxylase, ComD; TIGRFAM: Sulfopyruvate decarboxylase, alpha subunit. (163 aa)
ADZ08572.1Malate dehydrogenase (NADP(+)); KEGG: mmg:MTBMA_c15830 sulfolactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase. (343 aa)
comBPFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulpholactate phosphatase; HAMAP: 2-phosphosulpholactate phosphatase ComB; KEGG: mfv:Mfer_1236 2-phosphosulfolactate phosphatase. (222 aa)
ADZ08600.1Methanogenesis marker protein 10; KEGG: mmg:MTBMA_c15530 Fe-S oxidoreductase; TIGRFAM: Putative methanogenesis marker protein 10; PFAM: Domain of unknown function DUF512; Radical SAM. (423 aa)
ADZ08601.1TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mmg:MTBMA_c15520 methyl-coenzyme M reductase I, subunit beta; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal. (441 aa)
ADZ08602.1KEGG: mth:MTH1167 methyl coenzyme M reductase I, D protein; TIGRFAM: Methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D. (144 aa)
ADZ08603.1KEGG: mmg:MTBMA_c15500 methyl-coenzyme M reductase I, subunit epsilon; TIGRFAM: Methyl-coenzyme M reductase, protein C; PFAM: Methyl-coenzyme M reductase, protein C. (198 aa)
ADZ08604.1TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1165 methyl coenzyme M reductase I, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. (249 aa)
ADZ08605.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (550 aa)
mtrETetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (293 aa)
mtrDTetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (243 aa)
mtrCTetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (270 aa)
mtrBTetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (101 aa)
mtrATetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (239 aa)
mtrFTetrahydromethanopterin S-methyltransferase, F subunit; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (67 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (82 aa)
mtrHTetrahydromethanopterin S-methyltransferase subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (310 aa)
ADZ08614.1Anion transporter; KEGG: mth:MTH788 sodium/dicarboxylate or sulfate cotransporter; TIGRFAM: Sodium/sulphate symporter; PFAM: Sodium/sulphate symporter. (465 aa)
ADZ08615.1Methanogenesis marker protein 14; KEGG: mth:MTH1153 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP016937, methanogenesis; PFAM: Uncharacterised conserved protein UCP016937, methanogenesis. (488 aa)
ADZ08616.1PFAM: Acylneuraminate cytidylyltransferase; KEGG: mst:Msp_0310 GTP:adenosylcobinamide-phosphate guanylyltransferase. (220 aa)
ADZ08617.1PRC-barrel domain protein; PFAM: PRC-barrel; KEGG: mmg:MTBMA_c15350 hypothetical protein. (90 aa)
ADZ08620.1PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1136 methyl viologen-reducing hydrogenase, delta subunit. (142 aa)
ADZ08621.1PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: msi:Msm_1000 methyl viologen-reducing hydrogenase, gamma subunit, MvhG. (309 aa)
ADZ08622.1Hydrogen dehydrogenase; KEGG: mmg:MTBMA_c15170 F420-non-reducing hydrogenase, subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (470 aa)
ADZ08623.1PFAM: 4Fe-4S binding domain; KEGG: mth:MTH1133 polyferredoxin (MvhB). (412 aa)
ADZ08624.1PFAM: RNA-binding protein, predicted; KEGG: mfv:Mfer_0735 RNA-binding protein, predicted. (59 aa)
ADZ08628.1Hypothetical protein. (50 aa)
ADZ08629.1KEGG: mst:Msp_0326 hypothetical protein. (77 aa)
ADZ08630.1PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: mth:MTH1120 NifH / MinD related protein. (261 aa)
ADZ08641.1PFAM: Uncharacterised protein family, nitrogen regulatory protein PII-related; KEGG: mmg:MTBMA_c14940 transcriptional regulatory protein. (122 aa)
ADZ08657.1PFAM: Aspartate/glutamate/uridylate kinase; KEGG: mfv:Mfer_0582 aspartate/glutamate/uridylate kinase. (219 aa)
ADZ08659.1KEGG: mmg:MTBMA_c13710 hypothetical protein; TIGRFAM: Putative methanogenesis marker protein 1; YcaO-like; PFAM: YcaO-like. (399 aa)
ADZ08696.1PFAM: ATP-grasp fold, DUF201-type; KEGG: mfv:Mfer_0930 hypothetical protein. (388 aa)
cdhAAcetyl-CoA decarbonylase/synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (781 aa)
cdhBAcetyl-CoA decarbonylase/synthase complex subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family. (170 aa)
cdhCCO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (468 aa)
ADZ08717.1PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: mmp:MMP0982 hypothetical protein. (250 aa)
cdhDCO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. (386 aa)
cdhECO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). (462 aa)
ADZ08720.1PFAM: 4Fe-4S binding domain; KEGG: mmz:MmarC7_0221 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (156 aa)
ADZ08743.1KEGG: mth:MTH1741 hypothetical protein; TIGRFAM: Dihydropteroate synthase-related protein synthase-related protein; PFAM: Pterin-binding. (535 aa)
ADZ08760.1TIGRFAM: Methyl coenzyme M reductase system, component A2; PFAM: ABC transporter-like; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; SMART: ATPase, AAA+ type, core. (530 aa)
ADZ08761.1UPF0251 protein; KEGG: mmg:MTBMA_c15550 DNA-binding protein; HAMAP: Uncharacterised protein family UPF0251; PFAM: Uncharacterised protein family UPF0251; Belongs to the UPF0251 family. (203 aa)
mer5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (321 aa)
ADZ08825.1Coenzyme F420 hydrogenase; KEGG: mmg:MTBMA_c06440 F420-dependent glutamate synthase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal. (367 aa)
ADZ08874.1UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (220 aa)
ADZ08885.1PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: mfv:Mfer_0106 glutamate synthase alpha subunit domain protein. (308 aa)
ADZ08890.1Hydrogen dehydrogenase; KEGG: mpd:MCP_2492 F420-non-reducing hydrogenase subunit A; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (482 aa)
ADZ08891.1PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: mpd:MCP_2493 F420-non-reducing hydrogenase subunit G. (303 aa)
ADZ08933.1PFAM: Uncharacterised conserved protein UCP006598; KEGG: mmg:MTBMA_c04340 hypothetical protein. (376 aa)
ADZ08934.1Methanogenesis marker protein 2; KEGG: mmg:MTBMA_c04350 SelD-related protein; TIGRFAM: Putative methanogenesis marker protein 2; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal. (328 aa)
ADZ08935.1UPF0288 protein; KEGG: mmg:MTBMA_c04360 peptidyl-prolyl cis-trans isomerase related protein; TIGRFAM: Uncharacterised protein family UPF0288, methanogenesis; HAMAP: Uncharacterised protein family UPF0288, methanogenesis; Belongs to the UPF0288 family. (512 aa)
ADZ08936.1KEGG: mfv:Mfer_1092 methanogenesis marker protein 6; TIGRFAM: Uncharacterised conserved protein UCP005642, methanogenesis; PFAM: Uncharacterised conserved protein UCP005642, methanogenesis. (141 aa)
ADZ08937.1PFAM: Uncharacterised conserved protein UCP006557, signal transduction; KEGG: mfv:Mfer_1093 hypothetical protein. (127 aa)
ADZ08938.1Methanogenesis marker protein 5; KEGG: mth:MTH1868 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP018781, methanogenesis; PFAM: Uncharacterised conserved protein UCP018781, methanogenesis. (161 aa)
ADZ08939.1Methanogenesis marker protein 15; KEGG: mth:MTH1869 activator of (R)-2-hydroxyglutaryl-CoA; TIGRFAM: Putative methanogenesis marker protein 15; CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type. (410 aa)
ADZ08940.1Methanogenesis marker protein 17; KEGG: mth:MTH1870 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP019464, methanogenesis; PFAM: Uncharacterised conserved protein UCP019464, methanogenesis. (185 aa)
ADZ08941.1Radical SAM domain protein; KEGG: mth:MTH1871 nitrogenase iron-molybdenum cofactor biosynthesis protein NifB; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (283 aa)
ADZ08950.1PFAM: Queuine/other tRNA-ribosyltransferase; KEGG: mru:mru_0814 archaeosine tRNA-ribosyltransferase TgtA1. (243 aa)
ADZ08951.1KEGG: mth:MTH1878 heterodisulfide reductase, subunit C; TIGRFAM: CoB--CoM heterodisulphide reductase, subunit C. (331 aa)
ADZ08952.1TIGRFAM: CoB--CoM heterodisulphide reductase, subunit B; KEGG: mmg:MTBMA_c04500 CoB-CoM heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. (298 aa)
ADZ09010.1Protein of unknown function DUF88; KEGG: mmg:MTBMA_c04840 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00288; PFAM: Domain of unknown function DUF88. (163 aa)
ADZ09085.1TIGRFAM: Parallel beta-helix repeat-2; KEGG: mma:MM_0064 surface layer protein B. (745 aa)
ADZ09087.1PFAM: Protein of unknown function DUF166; 4Fe-4S binding domain; KEGG: mmp:MMP0986 thymidylate synthase. (313 aa)
ADZ09088.1Response regulator receiver protein; KEGG: mth:MTH374 dolichyl-phosphate mannose synthase related protein; PFAM: Glycosyl transferase, family 2; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain. (426 aa)
ADZ09113.1PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal; 4Fe-4S binding domain; KEGG: mth:MTH341 coenzyme F420-reducing hydrogenase, beta subunit-like protein. (426 aa)
ADZ09186.1Phosphoesterase RecJ domain protein; KEGG: mmg:MTBMA_c11580 archaea-specific RecJ-like exonuclease; PFAM: Phosphoesterase, RecJ-like; Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1. (724 aa)
mfnBUPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (237 aa)
ADZ09242.1ABC transporter related protein; KEGG: mmg:MTBMA_c06010 methyl-coenzyme M reductase component A2-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core. (565 aa)
ADZ09243.1PFAM: UspA; KEGG: mth:MTH153 hypothetical protein. (133 aa)
ADZ09244.1Hypothetical protein. (96 aa)
ADZ09245.1KEGG: iag:Igag_0802 DNA-(apurinic or apyrimidinic site) lyase; pyrimidine dimer DNA glycosylase. (143 aa)
ADZ09327.1PFAM: Triphosphoribosyl-dephospho-CoA protein; KEGG: mfv:Mfer_1255 triphosphoribosyl-dephospho-CoA protein. (305 aa)
ADZ09448.1Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (777 aa)
ADZ09449.1KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. (331 aa)
ADZ09450.1Heterodisulfide reductase subunit C, HdrC2; KEGG: mst:Msp_0125 HdrC2. (196 aa)
ADZ09491.1KEGG: msi:Msm_0083 heterodisulfide reductase, subunit B, HdrB; PFAM: Cysteine-rich domain. (314 aa)
ADZ09492.1Heterodisulfide reductase subunit C, HdrC2; KEGG: mst:Msp_0125 HdrC2. (195 aa)
ADZ09514.1Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; KEGG: mfv:Mfer_1096 formylmethanofuran-tetrahydromethanopterin formyltransferase; PFAM: Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal; Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal. (300 aa)
ADZ09532.1KEGG: mth:MTH384 hypothetical protein. (98 aa)
ADZ09608.1Protein of unknown function UPF0058; PFAM: Uncharacterised protein family UPF0058; KEGG: mmg:MTBMA_c06730 hypothetical protein. (109 aa)
ADZ09677.1TIGRFAM: Parallel beta-helix repeat-2; KEGG: mac:MA4577 cell surface protein. (385 aa)
ADZ09698.1Transcriptional regulator, TrmB; PFAM: Transcription regulator TrmB, N-terminal; KEGG: mmg:MTBMA_c00400 transcriptional regulator. (266 aa)
ADZ10160.1KEGG: mst:Msp_0377 hypothetical protein. (206 aa)
ADZ10161.1TIGRFAM: Methylthiotransferase; MiaB-like tRNA modifying enzyme, archaeal-type; PFAM: Methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; KEGG: mth:MTH826 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB. (425 aa)
pcmProtein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (216 aa)
ADZ10163.1KEGG: mst:Msp_0375 hypothetical protein. (208 aa)
ADZ10165.1Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (330 aa)
ADZ10166.1PFAM: Radical SAM; KEGG: mmg:MTBMA_c12290 Fe-S oxidoreductase. (500 aa)
ADZ10168.1H4MPT-linked C1 transfer pathway protein; KEGG: mth:MTH834 hypothetical protein; TIGRFAM: Tetrahydromethanopterin-linked C1 transfer pathway, putative; PFAM: Hydantoinase/oxoprolinase. (349 aa)
ADZ10169.1PFAM: ATP-grasp fold, DUF201-type; KEGG: mmg:MTBMA_c12330 ATP-utilizing enzyme. (339 aa)
ADZ10269.1Hydrogenase assembly chaperone hypC/hupF; KEGG: mmg:MTBMA_c02320 hydrogenase maturation factor HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC. (82 aa)
ADZ10288.1PFAM: Protein of unknown function DUF98; KEGG: mth:MTH1632 hypothetical protein. (177 aa)
ADZ10323.1KEGG: mst:Msp_1178 helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. (833 aa)
ADZ10340.1Regulatory protein Crp; SMART: HTH transcriptional regulator, Crp; KEGG: mst:Msp_1188 transcriptional regulator. (263 aa)
ADZ10348.1Methanogen marker protein 4; TIGRFAM: Methyltransferase Mtx, subunit X; KEGG: mfv:Mfer_0594 methanogen marker protein 4. (241 aa)
ADZ10365.1PFAM: Protein of unknown function DUF1802; KEGG: mth:MTH1210 mrr restriction system related protein. (170 aa)
ADZ10383.1KEGG: mth:MTH205 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein. (336 aa)
ADZ10392.1PFAM: Histidine biosynthesis; KEGG: mru:mru_1337 HisA/HisF family protein HisAF; Belongs to the HisA/HisF family. (223 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (320 aa)
ADZ10415.1KEGG: mmg:MTBMA_c11780 hydrogenase maturation factor HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like. (217 aa)
hypAHydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (128 aa)
ADZ10424.1Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (136 aa)
ADZ10425.1PFAM: Methyltransferase type 12; KEGG: mfv:Mfer_1049 RNA methylase. (261 aa)
ADZ10426.1KEGG: mmg:MTBMA_c11320 hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogenase maturation protease HycI; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein. (167 aa)
ADZ10449.1PFAM: TfuA-like, core; KEGG: mmg:MTBMA_c13720 hypothetical protein. (215 aa)
ADZ10454.1Protein of unknown function DUF129; PFAM: F420-0 gamma-glutamyl ligase-related; KEGG: mth:MTH1670 hypothetical protein. (279 aa)
ADZ10455.1PFAM: Putative Fe-S cluster; KEGG: mmg:MTBMA_c02500 hypothetical protein. (229 aa)
ADZ10456.1PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; KEGG: mth:MTH1672 hypothetical protein. (233 aa)
ADZ10457.1ABC transporter related protein; KEGG: mth:MTH1673 sn-glycerol-3-phosphate transport ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core. (258 aa)
ADZ10458.1TIGRFAM: Phosphosulpholactate synthase; KEGG: mth:MTH1674 hypothetical protein; PFAM: (2R)-phospho-3-sulpholactate synthase, ComA. (257 aa)
ADZ10477.1KEGG: mmg:MTBMA_c14600 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein. (352 aa)
ADZ10492.1TIGRFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mfv:Mfer_0731 methyl-coenzyme m reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit, C-terminal; Methyl-coenzyme M reductase, beta subunit, N-terminal. (443 aa)
ADZ10493.1KEGG: mst:Msp_0319 MrtD; TIGRFAM: Methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D. (162 aa)
ADZ10494.1TIGRFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mth:MTH1130 methyl coenzyme M reductase II, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit. (264 aa)
ADZ10495.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (550 aa)
ADZ10535.1Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; TIGRFAM: Archaeoflavoprotein AfpA; PFAM: Flavoprotein. (185 aa)
ADZ10556.1PFAM: Mur ligase, central; KEGG: mfv:Mfer_1205 mur ligase middle domain protein. (447 aa)
ADZ10565.1PFAM: Protein of unknown function DUF447; KEGG: mfv:Mfer_1266 hypothetical protein. (205 aa)
ADZ10566.1PFAM: Uncharacterised conserved protein UCP004962; KEGG: mth:MTH862 hypothetical protein. (153 aa)
ADZ10567.1Hypothetical protein; Manually curated; KEGG: mmg:MTBMA_c10980 hypothetical protein. (48 aa)
ADZ10651.1TIM-barrel protein; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, NifR3-related; KEGG: mfv:Mfer_0317 tim-barrel protein. (238 aa)
ADZ10652.1SMART: ATPase, AAA+ type, core; TIGRFAM: Methyl coenzyme M reductase system, component A2; KEGG: mmg:MTBMA_c13970 methyl-coenzyme M reductase, component A2; PFAM: ABC transporter-like. (533 aa)
ADZ10653.1TIGRFAM: Putative methanogenesis marker domain 9; KEGG: mth:MTH1014 hypothetical protein. (158 aa)
ADZ10656.1KEGG: msi:Msm_1725 hypothetical protein. (242 aa)
ADZ10657.1AAA ATPase central domain protein; KEGG: mth:MTH1011 ATP-dependent 26S protease regulatory subunit 8; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (373 aa)
ADZ10672.1Manually curated; TIGRFAM: Archaeoflavoprotein AfpA; KEGG: mtp:Mthe_0245 flavoprotein; PFAM: Flavoprotein. (191 aa)
ADZ10682.1Methanogenesis marker protein 8; KEGG: rci:LRC199 hypothetical protein; TIGRFAM: Uncharacterised conserved protein UCP004929, methanogenesis; PFAM: Uncharacterised conserved protein UCP004929, methanogenesis. (276 aa)
ADZ10690.1Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (771 aa)
ADZ10691.1KEGG: rci:LRC438 putative heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain. (306 aa)
ADZ10692.1PFAM: 4Fe-4S binding domain; KEGG: mpd:MCP_1991 putative CoB--CoM heterodisulfide reductase iron-sulfur subunit C. (204 aa)
ADZ10698.1PFAM: Domain of unknown function DUF128; Ribonuclease R winged-helix domain; KEGG: mmg:MTBMA_c01560 transcriptional repressor of nif & GlnA operons NrpR. (564 aa)
ADZ10714.1PFAM: 4Fe-4S binding domain; KEGG: msi:Msm_0784 ferredoxin. (63 aa)
ADZ10715.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: msi:Msm_0783 tungsten formylmethanofuran dehydrogenase, subunit F, FwdF. (334 aa)
ADZ10718.1PFAM: Formylmethanofuran dehydrogenase, subunit E domain; KEGG: mbu:Mbur_0286 formylmethanofuran dehydrogenase, subunit E. (198 aa)
ADZ10719.1PFAM: Protein of unknown function DUF2097; KEGG: mru:mru_0347 hypothetical protein. (102 aa)
ADZ10720.1PFAM: Protein of unknown function DUF2097; KEGG: mru:mru_0346 hypothetical protein. (100 aa)
ADZ10721.1TIGRFAM: Formylmethanofuran dehydrogenase subunit C; KEGG: mru:mru_0345 tungsten formylmethanofuran dehydrogenase subunit C FwdC; PFAM: Glutamate synthase, alpha subunit, C-terminal. (270 aa)
ADZ10722.1KEGG: mru:mru_0344 tungsten formylmethanofuran dehydrogenase subunit A FwdA; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A; PFAM: Amidohydrolase 3. (569 aa)
ADZ10723.1TIGRFAM: Formylmethanofuran dehydrogenase, subunit B; KEGG: msi:Msm_1412 tungsten formylmethanofuran dehydrogenase, subunit B, FwdB; PFAM: Molybdopterin oxidoreductase. (452 aa)
ADZ10724.1Molybdopterin dinucleotide-binding region; PFAM: Molydopterin dinucleotide-binding domain; KEGG: msi:Msm_1411 tungsten formylmethanofuran dehydrogenase, subunit D, FwdD. (178 aa)
ADZ10725.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0341 tungsten formylmethanofuran dehydrogenase subunit G FwdG. (76 aa)
ADZ10726.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; KEGG: mru:mru_0340 tungsten formylmethanofuran dehydrogenase subunit F FwdF. (347 aa)
ADZ10727.1PFAM: Helix-turn-helix type 3; 4Fe-4S binding domain; KEGG: mth:MTH1553 tungsten formylmethanofuran dehydrogenase, subunit H. (149 aa)
ADZ10728.1TIGRFAM: Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; KEGG: mth:MTH1552 formate dehydrogenase, alpha subunit-like protein; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding. (901 aa)
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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