STRINGSTRING
ADZ08367.1 ADZ08367.1 lysA lysA ADZ08430.1 ADZ08430.1 ADZ08556.1 ADZ08556.1 ADZ08570.1 ADZ08570.1 ADZ08571.1 ADZ08571.1 mfnA mfnA ADZ08647.1 ADZ08647.1 fbp fbp mfnB mfnB ADZ09272.1 ADZ09272.1 aroA-2 aroA-2 ADZ09662.1 ADZ09662.1 ADZ09880.1 ADZ09880.1 ADZ10085.1 ADZ10085.1 dapA dapA deoC deoC pyrF pyrF ADZ10265.1 ADZ10265.1 ADZ10266.1 ADZ10266.1 trpE trpE pdaD pdaD taw1 taw1 mptD mptD asd-2 asd-2 thiC thiC moaA moaA ADZ10738.1 ADZ10738.1 ADZ08299.1 ADZ08299.1 fae-hps fae-hps cobD cobD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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ADZ08367.1KEGG: mru:mru_2213 fuculose 1-phosphate aldolase FucA; PFAM: Class II aldolase/adducin, N-terminal. (195 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (428 aa)
ADZ08430.1UbiD family decarboxylase; KEGG: mst:Msp_1479 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Carboxylyase-related; PFAM: Carboxylyase-related. (428 aa)
ADZ08556.1TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; KEGG: mth:MTH1216 pantothenate metabolism flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein. (381 aa)
ADZ08570.1TIGRFAM: Sulfopyruvate decarboxylase, beta subunit; KEGG: mmg:MTBMA_c15850 sulfopyruvate decarboxylase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (182 aa)
ADZ08571.1KEGG: msi:Msm_0080 sulfopyruvate decarboxylase, ComD; TIGRFAM: Sulfopyruvate decarboxylase, alpha subunit. (163 aa)
mfnAL-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (392 aa)
ADZ08647.1TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmg:MTBMA_c14900 pyruvate carboxylase, subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment. (570 aa)
fbpProtein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa)
mfnBUPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (237 aa)
ADZ09272.1Methyltransferase MtaA/CmuA family; KEGG: msi:Msm_0518 methylcobalamin:coenzyme M methyltransferase, MtaA; TIGRFAM: Methyltransferase MtaA/CmuA; PFAM: Uroporphyrinogen decarboxylase (URO-D). (353 aa)
aroA-2Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (266 aa)
ADZ09662.1TIGRFAM: Glutamate decarboxylase; KEGG: cwo:Cwoe_3467 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase. (481 aa)
ADZ09880.1TIGRFAM: Glutamate decarboxylase; KEGG: mba:Mbar_A2744 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase. (491 aa)
ADZ10085.1Methylisocitrate lyase; KEGG: ccb:Clocel_0283 2,3-dimethylmalate lyase. (276 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (221 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (216 aa)
ADZ10265.1KEGG: mfv:Mfer_0096 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase. (278 aa)
ADZ10266.1TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; KEGG: mfv:Mfer_0097 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal. (191 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (461 aa)
pdaDKEGG: mth:MTH870 hypothetical protein; TIGRFAM: Pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family. (147 aa)
taw1Wyosine base formation domain-containing protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (306 aa)
mptDProtein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (122 aa)
asd-2Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily. (227 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (320 aa)
ADZ10738.1Phosphomethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; KEGG: mth:MTH1543 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC. (429 aa)
ADZ08299.13,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (227 aa)
fae-hpsBifunctional enzyme fae/hps; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (406 aa)
cobDCobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (309 aa)
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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