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| | lysS | PFAM: Lysyl-tRNA synthetase, class Ic; TIGRFAM: Lysyl-tRNA synthetase, class I; HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; KEGG: mth:MTH1542 hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (525 aa) |
| | ADZ08266.1 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: mth:MTH1793 hypothetical protein. (226 aa) |
| | leuS | TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: mst:Msp_0171 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (958 aa) |
| | ADZ08276.1 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: mmg:MTBMA_c00990 precorrin-6Y methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase. (207 aa) |
| | sepS | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (531 aa) |
| | gatA | Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa) |
| | ADZ10744.1 | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: mmg:MTBMA_c01230 anaerobic ribonucleotide-triphosphate reductase; PFAM: ATP-cone. (773 aa) |
| | ADZ08311.1 | PFAM: Xylose isomerase, TIM barrel domain; KEGG: mmg:MTBMA_c00720 sugar phosphate isomerase/epimerase. (253 aa) |
| | ADZ08321.1 | PHP domain protein; KEGG: mmg:MTBMA_c00610 phosphoesterase; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal. (216 aa) |
| | ADZ08336.1 | Manually curated; PFAM: Radical SAM; Helix-hairpin-helix motif; KEGG: mru:mru_2152 radical SAM domain-containing protein; SMART: Elongator protein 3/MiaB/NifB. (372 aa) |
| | thrS | TIGRFAM: Threonyl-tRNA synthetase, class IIa; KEGG: mth:MTH1455 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase, editing domain, archaea; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family. (614 aa) |
| | argS | KEGG: mth:MTH1447 arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. (561 aa) |
| | ADZ08350.1 | PFAM: Restriction endonuclease, type IV-like, Mrr; KEGG: mmg:MTBMA_c00210 hypothetical protein. (265 aa) |
| | rps15 | PFAM: Ribosomal protein S15; Ribosomal protein S13/S15, N-terminal; KEGG: mmg:MTBMA_c00110 30S ribosomal protein S15P. (133 aa) |
| | ADZ08360.1 | Helicase domain protein; KEGG: mth:MTH1415 Hef nuclease; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; ERCC4 domain; Helix-hairpin-helix DNA-binding motif, class 1. (769 aa) |
| | ADZ08361.1 | tRNA (adenine-N(1)-)-methyltransferase; Manually curated; KEGG: mth:MTH1414 protein-L-isoaspartate methyltransferase-like protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase. (242 aa) |
| | ADZ08363.1 | Cell division control protein 6-like protein; Involved in regulation of DNA replication. (382 aa) |
| | polB | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (501 aa) |
| | ADZ08378.1 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; HhH-GPD domain; KEGG: msi:Msm_1365 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; SMART: HhH-GPD domain. (328 aa) |
| | ADZ08381.1 | PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: Methylpurine-DNA glycosylase (MPG); HAMAP: Methylpurine-DNA glycosylase (MPG); KEGG: ccb:Clocel_1348 DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family. (202 aa) |
| | ADZ08382.1 | KEGG: glo:Glov_0058 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase. (186 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1060 aa) |
| | radA | DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa) |
| | ADZ08419.1 | Replication factor-A domain protein; PFAM: Replication factor A, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mmg:MTBMA_c17710 replication factor A. (793 aa) |
| | rsmA | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (273 aa) |
| | rpl21e | KEGG: mmg:MTBMA_c17090 50S ribosomal protein L21e; HAMAP: Ribosomal protein L21e, archaeal; PFAM: Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa) |
| | csl4 | RNA-binding domain, S1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | ADZ08454.1 | PFAM: NUDIX hydrolase domain; KEGG: mst:Msp_1534 putative ADP-ribose pyrophosphatase. (134 aa) |
| | pcn | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (244 aa) |
| | rpl44e | Ribosomal protein L44E; Binds to the 23S rRNA. (93 aa) |
| | rps27e | KEGG: mmg:MTBMA_c16950 30S ribosomal protein S27e; HAMAP: Ribosomal protein S27e, archaea; PFAM: Ribosomal protein S27e. (64 aa) |
| | eif2a | Translation initiation factor 2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (259 aa) |
| | dnaJ | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (388 aa) |
| | ADZ08488.1 | KEGG: mmg:MTBMA_c15860 DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B. (598 aa) |
| | hjc | Resolvase, Holliday junction-type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (136 aa) |
| | gatB | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (452 aa) |
| | trm1 | N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (386 aa) |
| | ADZ08591.1 | PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; KEGG: mfv:Mfer_1241 translation elongation factor 1a gtp binding domain family. (529 aa) |
| | ADZ08596.1 | PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mev:Metev_2175 deoxyribonuclease/rho motif-like TRAM protein. (66 aa) |
| | rpl10e | TIGRFAM: Ribosomal protein L10e; HAMAP: Ribosomal protein L10e, archaea; KEGG: mmg:MTBMA_c15020 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family. (160 aa) |
| | ADZ08637.1 | tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (184 aa) |
| | ADZ08648.1 | KEGG: mmg:MTBMA_c10340 hypothetical protein. (527 aa) |
| | ef1b | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | pth | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (113 aa) |
| | ADZ08668.1 | t-RNA-binding domain-containing protein; PFAM: tRNA-binding domain; KEGG: ton:TON_0446 putative tRNA-binding protein. (237 aa) |
| | ADZ08683.1 | TIGRFAM: ATPase, A1A0, subunit H; KEGG: mth:MTH961 hypothetical protein. (104 aa) |
| | ADZ08721.1 | KEGG: mfv:Mfer_0521 methylated-DNA/protein-cysteinemethyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding. (191 aa) |
| | ADZ08758.1 | PFAM: Radical SAM; KEGG: kcr:Kcr_0677 radical SAM domain-containing protein. (295 aa) |
| | mutS2 | DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (630 aa) |
| | ADZ08769.1 | Uncharacterized protein family UPF0066; KEGG: afu:AF0241 hypothetical protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066. (134 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (322 aa) |
| | eif2b | Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa) |
| | rlmE | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (204 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (775 aa) |
| | ADZ08786.1 | PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mmg:MTBMA_c02090 oligosaccharyl transferase STT3 subunit related protein. (816 aa) |
| | ADZ08787.1 | Small GTP-binding protein; KEGG: mth:MTH1621 GTP1/OBG family GTP-binding protein; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; TGS. (364 aa) |
| | rps19e | Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (145 aa) |
| | rpl39e | KEGG: tga:TGAM_1684 50S ribosomal protein L39e; HAMAP: 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rpl31e | KEGG: mfv:Mfer_0167 lsu ribosomal protein l31e; HAMAP: Ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (81 aa) |
| | eif6 | Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa) |
| | rpl18a | HAMAP: Ribosomal protein LX; KEGG: mmg:MTBMA_c01960 50S ribosomal protein LX. (76 aa) |
| | ADZ08813.1 | Cell division control protein 6-like protein; Involved in regulation of DNA replication. (376 aa) |
| | radB | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (232 aa) |
| | ADZ08843.1 | Manually curated; PFAM: ABC transporter-like; RNase L inhibitor RLI, possible metal-binding domain; 4Fe-4S binding domain; KEGG: mth:MTH1695 putative ATPase RIL; SMART: ATPase, AAA+ type, core. (591 aa) |
| | ADZ08846.1 | PFAM: tRNA-specific 2-thiouridylase; KEGG: mru:mru_1475 hypothetical protein. (363 aa) |
| | rps27ae | KEGG: mst:Msp_0620 30S ribosomal protein S27ae; HAMAP: Ribosomal protein S27ae; PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family. (54 aa) |
| | rps24e | KEGG: mth:MTH267 30S ribosomal protein S24e; HAMAP: 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (101 aa) |
| | eif2g | Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa) |
| | rps6e | KEGG: mth:MTH260 30S ribosomal protein S6e; HAMAP: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (125 aa) |
| | infB | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa) |
| | rpl24e | 50S ribosomal protein L24e; Binds to the 23S rRNA. (53 aa) |
| | rps28e | KEGG: mst:Msp_0632 30S ribosomal protein S28e; HAMAP: Ribosomal protein S28e, archaeal; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (365 aa) |
| | ADZ08870.1 | PFAM: Xylose isomerase, TIM barrel domain; KEGG: mfv:Mfer_1192 xylose isomerase domain protein tim barrel. (251 aa) |
| | hisS | ATP phosphoribosyltransferase regulatory subunit; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: ATP phosphoribosyltransferase regulatory subunit; Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: mth:MTH244 histidyl-tRNA synthetase. (429 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (491 aa) |
| | rfcS | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (347 aa) |
| | ADZ08906.1 | KEGG: mmg:MTBMA_c04090 hypothetical protein. (411 aa) |
| | ADZ08912.1 | KEGG: mmg:MTBMA_c04160 glycyl-tRNA synthetase; TIGRFAM: Glycyl-tRNA synthetase, alpha2 dimer; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding. (575 aa) |
| | ADZ08914.1 | KEGG: mst:Msp_1047 rRNA methylase; TIGRFAM: RNA methyltransferase TrmH, group 1; PFAM: tRNA/rRNA methyltransferase, SpoU. (233 aa) |
| | ADZ08945.1 | DNA adenine methylase; Manually curated; TIGRFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: tit:Thit_0485 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase. (302 aa) |
| | ADZ08961.1 | HhH-GPD family protein; KEGG: mac:MA3207 DNA-3-methyladenine glycosylase II; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. (295 aa) |
| | ADZ08970.1 | PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: mth:MTH1623 oligosaccharyl transferase STT3 subunit related protein. (800 aa) |
| | ADZ08972.1 | PFAM: Glycosyl transferase, group 1; KEGG: mpd:MCP_0893 putative glycosyltransferase. (394 aa) |
| | ADZ08977.1 | PFAM: Glycosyl transferase, family 2; KEGG: pab:PAB0795 rhamnosyl transferase related protein. (331 aa) |
| | ADZ08991.1 | PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; KEGG: mmg:MTBMA_c04780 hypothetical protein. (661 aa) |
| | rpl3 | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (337 aa) |
| | rpl4 | 50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (260 aa) |
| | rpl23 | Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (85 aa) |
| | rpl2 | Ribosomal protein L2, C-terminal; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rps19p | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (137 aa) |
| | rpl22 | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (153 aa) |
| | rps3 | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (299 aa) |
| | rpl29 | KEGG: msi:Msm_0755 50S ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; PFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | ADZ09033.1 | TIGRFAM: Archaeal/bacterial translation initiation factor SUI1; HAMAP: Translation factor SUI1 homolog, archaea; KEGG: mru:mru_0859 translation initiation factor aSUI1; PFAM: Translation initiation factor SUI1; Belongs to the SUI1 family. (111 aa) |
| | rps17 | Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (106 aa) |
| | rpl14 | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rpl24 | Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (117 aa) |
| | rps4e | HAMAP: Ribosomal protein S4e, archaea; PFAM: Ribosomal protein S4e, central; Ribosomal protein S4e, N-terminal; RNA-binding S4; KEGG: mmg:MTBMA_c05040 30S ribosomal protein S4e; SMART: RNA-binding S4; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa) |
| | rpl5 | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (168 aa) |
| | ADZ09040.1 | KEGG: mth:MTH17 30S ribosomal protein S14P; manually curated; PFAM: Ribosomal protein S14. (47 aa) |
| | rps8 | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6 | Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | ADZ09043.1 | PFAM: Ribosomal protein L32e; KEGG: mru:mru_0869 ribosomal protein L32e Rpl32e. (114 aa) |
| | rpl19e | Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa) |
| | rpl18 | Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rps5 | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (215 aa) |
| | rpl30 | KEGG: mmg:MTBMA_c05130 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal; PFAM: Ribosomal protein L30, ferredoxin-like fold domain. (159 aa) |
| | rpl15 | 50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rpl34e | KEGG: mmg:MTBMA_c05180 50S ribosomal protein L34E; HAMAP: 50S ribosomal protein L34e; PFAM: Ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa) |
| | ADZ09054.1 | KEGG: mst:Msp_0880 50S ribosomal protein L14e. (76 aa) |
| | rps13 | Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | rps4 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (178 aa) |
| | rps11 | Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rpl18e | HAMAP: Ribosomal protein L18e, archaea; KEGG: msi:Msm_1429 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rpl13 | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa) |
| | rps9 | KEGG: mth:MTH39 ribosomal protein S16; TIGRFAM: Ribosomal protein S9, archaeal; PFAM: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (133 aa) |
| | rps2 | KEGG: mth:MTH44 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (198 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (449 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (564 aa) |
| | ADZ09088.1 | Response regulator receiver protein; KEGG: mth:MTH374 dolichyl-phosphate mannose synthase related protein; PFAM: Glycosyl transferase, family 2; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain. (426 aa) |
| | ADZ09107.1 | PFAM: Glycosyl transferase, group 1; KEGG: dol:Dole_1802 glycosyl transferase group 1. (343 aa) |
| | ADZ09109.1 | PFAM: Glycosyl transferase, group 1; KEGG: ton:TON_1855 glycosyltransferase. (352 aa) |
| | ADZ09137.1 | PFAM: Glycosyl transferase, group 1; KEGG: apo:Arcpr_0515 glycosyl transferase group 1. (380 aa) |
| | ADZ09138.1 | KEGG: mmg:MTBMA_c10340 hypothetical protein. (525 aa) |
| | ADZ09139.1 | PFAM: Glycosyl transferase, group 1; KEGG: tit:Thit_0644 glycosyl transferase group 1. (392 aa) |
| | ADZ09141.1 | PFAM: Glycosyl transferase, family 2; KEGG: pab:PAB0795 rhamnosyl transferase related protein. (355 aa) |
| | ADZ09147.1 | PFAM: Glycosyl transferase, family 2; KEGG: mru:mru_0112 glycosyl transferase GT2 family. (293 aa) |
| | ADZ09148.1 | PFAM: Glycosyl transferase, family 2; KEGG: msi:Msm_1329 glycosyl transferase. (316 aa) |
| | ADZ09153.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | ADZ09168.1 | TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form; KEGG: mth:MTH1791 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase. (293 aa) |
| | ADZ09169.1 | TIGRFAM: dTDP-4-dehydrorhamnose reductase; KEGG: mfv:Mfer_0285 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase. (280 aa) |
| | nth | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (216 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (887 aa) |
| | pheT | Phenylalanyl-tRNA synthetase beta chain; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: mmg:MTBMA_c11660 phenylalanyl-tRNA synthetase, beta chain; HAMAP: Phenylalanyl-tRNA synthetase beta chain 2, bacterial/archaeal; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain. (553 aa) |
| | ADZ09214.1 | PFAM: Domain of unknown function DUF752; KEGG: mmg:MTBMA_c06280 hypothetical protein. (427 aa) |
| | ADZ09218.1 | PFAM: Glycosyl transferase, group 1; KEGG: mem:Memar_0690 glycosyl transferase, group 1. (396 aa) |
| | cbiT | cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (187 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa) |
| | pheS | TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; KEGG: mmg:MTBMA_c11370 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (522 aa) |
| | ADZ09330.1 | HhH-GPD family protein; KEGG: mba:Mbar_A3333 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD domain; SMART: HhH-GPD domain. (238 aa) |
| | uvrA | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (968 aa) |
| | uvrB | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (653 aa) |
| | ADZ09358.1 | PFAM: DNA methylase, adenine-specific; KEGG: mmq:MmarC5_1169 N-6 DNA methylase. (505 aa) |
| | ADZ09359.1 | PFAM: Restriction endonuclease, type I, S subunit, EcoBI; KEGG: mmw:Mmwyl1_3199 restriction modification system DNA specificity subunit. (403 aa) |
| | ADZ09361.1 | Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase, N-terminal; manually curated; KEGG: mmq:MmarC5_1171 type III restriction enzyme, res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Helicase, C-terminal. (911 aa) |
| | ADZ09386.1 | Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: msi:Msm_1640 DNA intergrase/recombinase. (423 aa) |
| | uvrC | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (590 aa) |
| | cysS | SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; KEGG: mst:Msp_0124 hypothetical protein; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. (467 aa) |
| | ADZ09462.1 | KEGG: mmg:MTBMA_c10340 hypothetical protein. (535 aa) |
| | ADZ09545.1 | PFAM: Glycosyl transferase, family 2; KEGG: ppm:PPSC2_c4821 glycosyl transferase family 2. (277 aa) |
| | ADZ09546.1 | PFAM: Glycosyl transferase, family 2; KEGG: mfv:Mfer_1072 glycosyl transferase family 2. (334 aa) |
| | ADZ09548.1 | PFAM: Glycosyl transferase, group 1; KEGG: mst:Msp_0044 glycosyltransferase. (406 aa) |
| | ADZ09550.1 | PFAM: Glycosyl transferase, family 2; KEGG: mst:Msp_0045 glycosyltransferase. (318 aa) |
| | ADZ09558.1 | PFAM: Glycosyl transferase, group 1; KEGG: mst:Msp_0052 glycosyltransferase. (372 aa) |
| | ADZ09559.1 | PFAM: Glycosyl transferase, group 1; KEGG: mth:MTH332 LPS biosynthesis RfbU related protein. (379 aa) |
| | ADZ09560.1 | PFAM: Glycosyl transferase, family 2; KEGG: mac:MA1187 dolichyl-phosphate beta-D-mannosyltransferase. (376 aa) |
| | ADZ09568.1 | MCP methyltransferase/methylesterase, CheR/CheB; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type. (978 aa) |
| | ADZ09582.1 | PFAM: Resolvase, helix-turn-helix domain; AT hook, DNA-binding motif; KEGG: mmg:MTBMA_c09690 hypothetical protein. (152 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (658 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (461 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (325 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | ogt | methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (190 aa) |
| | ADZ09639.1 | KEGG: mba:Mbar_A1645 phenylacetic acid degradation protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily. (136 aa) |
| | ADZ09658.1 | PHP domain protein; KEGG: mmg:MTBMA_c09400 DNA polymerase IV; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal. (569 aa) |
| | ADZ09712.1 | Heat shock protein DnaJ domain protein; KEGG: pfh:PFHG_00645 hypothetical protein similar to chaperone protein J; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal. (648 aa) |
| | ADZ09781.1 | KEGG: hso:HS_1260 hypothetical protein. (356 aa) |
| | ADZ09788.1 | PFAM: DNA helicase, UvrD/REP type; KEGG: mru:mru_1111 ATP-dependent DNA helicase UvrD/REP family. (786 aa) |
| | ADZ09791.1 | SMC domain protein; PFAM: RecF/RecN/SMC; KEGG: rlg:Rleg_1580 SMC domain protein. (815 aa) |
| | ADZ09801.1 | KEGG: lsl:LSL_1492 hypothetical protein. (242 aa) |
| | ADZ09803.1 | KEGG: mst:Msp_1507 putative DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, exonuclease domain; DNA-directed DNA polymerase, family B, conserved region; SMART: DNA-directed DNA polymerase, family B. (579 aa) |
| | ADZ09868.1 | PFAM: DNA helicase, UvrD/REP type; KEGG: mmg:MTBMA_c08650 ATP-dependent DNA helicase. (933 aa) |
| | ADZ09912.1 | TIGRFAM: Parallel beta-helix repeat-2; KEGG: msi:Msm_0281 putative adhesin-like protein. (618 aa) |
| | ADZ09993.1 | PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mth:MTH1263 hypothetical protein. (73 aa) |
| | ADZ09994.1 | PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mth:MTH1263 hypothetical protein. (73 aa) |
| | ADZ10017.1 | PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: mmg:MTBMA_c16500 hypothetical protein. (78 aa) |
| | ADZ10094.1 | DEAD/H associated domain protein; KEGG: mth:MTH1802 ATP-dependent helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; ATPase, AAA+ type, core; Helicase, C-terminal. (863 aa) |
| | polC | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1108 aa) |
| | ADZ10095.1 | Phosphoesterase; KEGG: mmg:MTBMA_c03740 phosphoesterase; TIGRFAM: Conserved hypothetical protein CHP00024; PFAM: Metallo-dependent phosphatase. (245 aa) |
| | nucS | UPF0286 protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (257 aa) |
| | rps17e | KEGG: msi:Msm_0833 30S ribosomal protein S17e; HAMAP: Ribosomal protein S17e; PFAM: Ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa) |
| | hel308 | DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (690 aa) |
| | ADZ10159.1 | Hypothetical protein. (63 aa) |
| | pcm | Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (216 aa) |
| | ADZ10163.1 | KEGG: mst:Msp_0375 hypothetical protein. (208 aa) |
| | pelA | Pelota-like protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (355 aa) |
| | fen | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (328 aa) |
| | rad50 | SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (900 aa) |
| | mre11 | Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (381 aa) |
| | ADZ10298.1 | KEGG: mru:mru_1103 hypothetical protein; PFAM: NurA domain; SMART: NurA domain. (360 aa) |
| | rpl37e | 50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (60 aa) |
| | ADZ10321.1 | Universal PUA-domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP03684; Uncharacterised domain 2; PFAM: Pseudouridine synthase/archaeosine transglycosylase; KEGG: mth:MTH650 putative RNA-binding protein; SMART: Pseudouridine synthase/archaeosine transglycosylase. (146 aa) |
| | ADZ10323.1 | KEGG: mst:Msp_1178 helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. (833 aa) |
| | ADZ10342.1 | PHP domain protein; Manually curated; PFAM: PHP, C-terminal; KEGG: mst:Msp_1186 hypothetical protein; SMART: Polymerase/histidinol phosphatase, N-terminal. (221 aa) |
| | ADZ10346.1 | KEGG: mfv:Mfer_0596 hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related. (252 aa) |
| | ADZ10365.1 | PFAM: Protein of unknown function DUF1802; KEGG: mth:MTH1210 mrr restriction system related protein. (170 aa) |
| | ADZ10372.1 | KEGG: bcg:BCG9842_B5359 P4 family phage/plasmid primase; TIGRFAM: DNA primase, phage/plasmid; PFAM: Phage/plasmid primase, P4, C-terminal. (584 aa) |
| | ADZ10379.1 | Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: mac:MA2582 hypothetical protein. (416 aa) |
| | rps8e | TIGRFAM: Ribosomal protein S8e; HAMAP: Ribosomal protein S8e, archaeal; KEGG: mth:MTH207 30S ribosomal protein S8e; PFAM: Ribosomal protein S8e/ribosomal biogenesis NSA2. (126 aa) |
| | ADZ10386.1 | KEGG: mfv:Mfer_0221 replicative DNA polymerase I; PFAM: DNA-directed DNA polymerase, family B, conserved region. (219 aa) |
| | rpl37ae | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. (89 aa) |
| | rrp42 | 3' exoribonuclease; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (263 aa) |
| | rrp41 | Exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (243 aa) |
| | psmA | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (249 aa) |
| | rpl15e | KEGG: mmg:MTBMA_c10770 50S ribosomal protein L15e; HAMAP: Ribosomal protein L15e, archaeal; PFAM: Ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (181 aa) |
| | ADZ10425.1 | PFAM: Methyltransferase type 12; KEGG: mfv:Mfer_1049 RNA methylase. (261 aa) |
| | ADZ10428.1 | KEGG: mth:MTH735 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site. (357 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | ADZ10452.1 | Metal dependent phosphohydrolase; TIGRFAM: HD-related protein; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: mru:mru_0474 HD domain-containing protein; SMART: Metal-dependent phosphohydrolase, HD domain. (169 aa) |
| | spt5 | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (147 aa) |
| | rpl11 | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (162 aa) |
| | rpl1 | Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rpl10 | Acidic ribosomal protein P0-like protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (333 aa) |
| | rpl12 | 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (905 aa) |
| | rpl40e | HAMAP: 50S ribosomal protein L40e; KEGG: mmg:MTBMA_c09420 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | ADZ10497.1 | PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; KEGG: mbn:Mboo_0327 putative PAS/PAC sensor protein; SMART: MCP methyltransferase, CheR-type. (290 aa) |
| | rps3ae | KEGG: mmg:MTBMA_c01790 30S ribosomal protein S3Ae; HAMAP: 30S ribosomal protein S3Ae; PFAM: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (194 aa) |
| | xerA | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily. (331 aa) |
| | dnaG | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (381 aa) |
| | prf1 | Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (409 aa) |
| | eif5a | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (131 aa) |
| | ADZ10573.1 | Protein of unknown function DUF650; Involved in DNA damage repair. (388 aa) |
| | ADZ10578.1 | TIGRFAM: Conserved hypothetical protein CHP01177; PFAM: Putative RNA methylase; THUMP; KEGG: mfv:Mfer_0515 RNA methylase; SMART: THUMP. (351 aa) |
| | eif1a | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (101 aa) |
| | top6B | DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (538 aa) |
| | top6A | Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (358 aa) |
| | ADZ10594.1 | PHP domain protein; KEGG: mba:Mbar_A1414 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal. (210 aa) |
| | ADZ10595.1 | O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (379 aa) |
| | ADZ10598.1 | PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: afu:AF1725 DNA ligase, putative. (301 aa) |
| | ADZ10599.1 | Ku domain protein; KEGG: mpd:MCP_0581 hypothetical protein; PFAM: DNA helicase, ATP-dependent, Ku type; SMART: DNA helicase, ATP-dependent, Ku type. (254 aa) |
| | rps10 | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa) |
| | rps7 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa) |
| | rps12 | Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | rpl30e | KEGG: mmg:MTBMA_c14400 50S ribosomal protein L30e; HAMAP: Ribosomal protein L30e; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (204 aa) |
| | ADZ10658.1 | KEGG: msi:Msm_0963 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV. (278 aa) |
| | gatE | Glutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (626 aa) |
| | gatD | Glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (437 aa) |
| | ADZ10662.1 | TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; KEGG: mmg:MTBMA_c06610 DNA lyase; PFAM: Endonuclease/exonuclease/phosphatase. (257 aa) |
| | lig | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (560 aa) |
| | ADZ10699.1 | Uncharacterized protein family UPF0066; KEGG: mru:mru_2214 hypothetical protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066. (164 aa) |
