STRINGSTRING
ADZ10574.1 ADZ10574.1 ADZ10595.1 ADZ10595.1 ADZ08424.1 ADZ08424.1 ADZ08588.1 ADZ08588.1 mfnA mfnA ADZ08815.1 ADZ08815.1 ADZ08841.1 ADZ08841.1 ADZ08962.1 ADZ08962.1 ADZ08964.1 ADZ08964.1 ADZ09011.1 ADZ09011.1 dapL dapL ADZ09428.1 ADZ09428.1 ADZ09455.1 ADZ09455.1 iscS iscS glyA-2 glyA-2 ADZ09510.1 ADZ09510.1 ADZ09662.1 ADZ09662.1 ADZ09880.1 ADZ09880.1 ADZ10057.1 ADZ10057.1 ADZ10070.1 ADZ10070.1 argD argD hemL hemL hisC hisC glyA glyA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ10574.1KEGG: mfv:Mfer_0512 hypothetical protein; Belongs to the DegT/DnrJ/EryC1 family. (328 aa)
ADZ10595.1O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (379 aa)
ADZ08424.1Cysteine desulfurase; KEGG: mmg:MTBMA_c17750 cystein desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase. (402 aa)
ADZ08588.1Glutamine--scyllo-inositol transaminase; KEGG: mmg:MTBMA_c15650 pyridoxal phosphate-dependent enzyme; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (364 aa)
mfnAL-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (392 aa)
ADZ08815.1Serine--pyruvate transaminase; KEGG: mmg:MTBMA_c01880 aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase. (389 aa)
ADZ08841.1KEGG: mmg:MTBMA_c02720 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII. (390 aa)
ADZ08962.1Putative transcriptional regulator, GntR family; KEGG: rci:RRC4 putative aminotransferase; PFAM: Aminotransferase, class I/classII. (392 aa)
ADZ08964.1KEGG: mmg:MTBMA_c04630 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII. (372 aa)
ADZ09011.1TIGRFAM: Pyridoxal phosphate-dependent transferase, archaea; KEGG: msi:Msm_0767 selenocysteine synthase, SelA. (386 aa)
dapLLL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa)
ADZ09428.1Cystathionine beta-lyase; KEGG: dly:Dehly_0142 class I and II aminotransferase; PFAM: Aminotransferase, class I/classII. (400 aa)
ADZ09455.1TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: mbu:Mbur_0797 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (439 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (387 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (421 aa)
ADZ09510.1KEGG: bba:Bd3795 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (377 aa)
ADZ09662.1TIGRFAM: Glutamate decarboxylase; KEGG: cwo:Cwoe_3467 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase. (481 aa)
ADZ09880.1TIGRFAM: Glutamate decarboxylase; KEGG: mba:Mbar_A2744 glutamate decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase. (491 aa)
ADZ10057.1Aspartate 4-decarboxylase; KEGG: sna:Snas_3840 aminotransferase class I and II; TIGRFAM: Aspartate 4-decarboxylase; PFAM: Aminotransferase, class I/classII. (546 aa)
ADZ10070.1KEGG: mma:MM_1955 cysteine desulfurase NifS; PFAM: Aminotransferase, class V/Cysteine desulfurase. (388 aa)
argDPFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: mfv:Mfer_0532 acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (390 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: mfv:Mfer_0593 glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (420 aa)
hisCPFAM: Aminotransferase, class I/classII; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: mth:MTH1587 histidinol-phosphate aminotransferase. (366 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (421 aa)
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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