STRINGSTRING
ADZ08634.1 ADZ08634.1 ADZ08647.1 ADZ08647.1 ADZ08681.1 ADZ08681.1 ADZ08736.1 ADZ08736.1 ADZ08739.1 ADZ08739.1 ADZ08740.1 ADZ08740.1 ADZ08741.1 ADZ08741.1 ADZ08742.1 ADZ08742.1 ADZ08830.1 ADZ08830.1 sucD sucD ADZ08995.1 ADZ08995.1 ADZ09015.1 ADZ09015.1 ADZ09693.1 ADZ09693.1 ADZ09694.1 ADZ09694.1 ADZ10270.1 ADZ10270.1 ADZ10331.1 ADZ10331.1 ADZ10332.1 ADZ10332.1 sucC sucC ADZ10619.1 ADZ10619.1 ADZ10620.1 ADZ10620.1 ADZ10621.1 ADZ10621.1 ADZ10622.1 ADZ10622.1 ADZ10663.1 ADZ10663.1 ADZ10664.1 ADZ10664.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADZ08634.1PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; KEGG: msi:Msm_0929 fumarate hydratase, FumA. (167 aa)
ADZ08647.1TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmg:MTBMA_c14900 pyruvate carboxylase, subunit B; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment. (570 aa)
ADZ08681.1KEGG: mth:MTH963 fumarate hydratase, class I related protein; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain. (285 aa)
ADZ08736.1TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; KEGG: mth:MTH1735 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain. (282 aa)
ADZ08739.1KEGG: mth:MTH1738 pyruvate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ08740.1KEGG: mmg:MTBMA_c03140 pyruvate synthase, subunit A; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (382 aa)
ADZ08741.1KEGG: mmg:MTBMA_c03150 pyruvate synthase, subunit D; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S binding domain. (80 aa)
ADZ08742.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; KEGG: mth:MTH1740 pyruvate ferredoxin oxidoreductase subunit gamma/delta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (177 aa)
ADZ08830.1HAMAP: Malate dehydrogenase, NAD-dependent; KEGG: mmg:MTBMA_c06400 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; Belongs to the LDH/MDH superfamily. (315 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (286 aa)
ADZ08995.1TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; KEGG: mst:Msp_0791 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain. (182 aa)
ADZ09015.1SMART: Biotin carboxylase, C-terminal; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: mmg:MTBMA_c04880 pyruvate carboxylase, subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal. (495 aa)
ADZ09693.1KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (573 aa)
ADZ09694.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: ppd:Ppro_0548 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ10270.1KEGG: mst:Msp_1077 dihydrolipoamide dehydrogenase-related protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (432 aa)
ADZ10331.1TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: mmh:Mmah_0726 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: Ferredoxin. (257 aa)
ADZ10332.1TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: mmh:Mmah_0725 succinate dehydrogenase subunit A; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal. (596 aa)
sucCSuccinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (368 aa)
ADZ10619.1KEGG: mru:mru_1826 2-oxoglutarate ferredoxin oxidoreductase subunit gamma KorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (182 aa)
ADZ10620.1KEGG: mth:MTH1034 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (288 aa)
ADZ10621.1KEGG: mmg:MTBMA_c14150 2-oxoglutarate synthase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal. (375 aa)
ADZ10622.1PFAM: 4Fe-4S binding domain; KEGG: mfv:Mfer_0036 2-oxoglutarate ferredoxin oxidoreductase, delta subunit. (69 aa)
ADZ10663.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: mmg:MTBMA_c09240 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (286 aa)
ADZ10664.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: mmg:MTBMA_c09230 pyruvate flavodoxin/ferredoxin oxidoreductase, subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (571 aa)
Your Current Organism:
Methanobacterium lacus
NCBI taxonomy Id: 877455
Other names: DSM 24406, JCM 17760, M. lacus, Methanobacterium lacus Borrel et al. 2012, Methanobacterium sp. 17A1, Methanobacterium sp. AL-21, strain 17A1
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