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guaB guaB gmk gmk gpt gpt shn_17740 shn_17740 shn_18730 shn_18730 shn_21450 shn_21450 guaA guaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (498 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (219 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa)
shn_17740Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)
shn_18730GMP synthase; Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
shn_21450GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa)
Your Current Organism:
Shinella sp. HZN7
NCBI taxonomy Id: 879274
Other names: S. sp. HZN7
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