STRINGSTRING
shn_10840 shn_10840 shn_10830 shn_10830 shn_10470 shn_10470 shn_10225 shn_10225 shn_10185 shn_10185 shn_10120 shn_10120 shn_09840 shn_09840 shn_09815 shn_09815 shn_09775 shn_09775 shn_09725 shn_09725 shn_09695 shn_09695 shn_09685 shn_09685 pyrH pyrH shn_09250 shn_09250 anmK anmK tmk tmk shn_08550 shn_08550 shn_08515 shn_08515 shn_08020 shn_08020 shn_07920 shn_07920 shn_07770 shn_07770 adk adk nadK nadK shn_06735 shn_06735 shn_06565 shn_06565 ndk ndk gmk gmk shn_05950 shn_05950 shn_05800 shn_05800 shn_11115 shn_11115 shn_05785 shn_05785 shn_05695 shn_05695 shn_05610 shn_05610 shn_05600 shn_05600 shn_05560 shn_05560 shn_05405 shn_05405 ppk ppk shn_05030 shn_05030 shn_04595 shn_04595 shn_04535 shn_04535 shn_04510 shn_04510 shn_04410 shn_04410 shn_04325 shn_04325 thrB thrB shn_04185 shn_04185 ispE ispE shn_03765 shn_03765 shn_03725 shn_03725 lpxK lpxK shn_03640 shn_03640 shn_03615 shn_03615 shn_03200 shn_03200 mtnK mtnK shn_02845 shn_02845 shn_02645 shn_02645 shn_02630 shn_02630 shn_02440 shn_02440 shn_02290 shn_02290 shn_02055 shn_02055 shn_01905 shn_01905 shn_01490 shn_01490 shn_01485 shn_01485 shn_01470 shn_01470 cmk cmk shn_01260 shn_01260 shn_00930 shn_00930 shn_00795 shn_00795 shn_00705 shn_00705 shn_00660 shn_00660 shn_00520 shn_00520 shn_00515 shn_00515 shn_00475 shn_00475 shn_00415 shn_00415 shn_00395 shn_00395 shn_00350 shn_00350 argB argB rbsK rbsK shn_00115 shn_00115 shn_11305 shn_11305 pfp pfp shn_12135 shn_12135 shn_12250 shn_12250 shn_12265 shn_12265 shn_12320 shn_12320 shn_12770 shn_12770 prs prs tdk tdk shn_13290 shn_13290 glpK glpK shn_13420 shn_13420 shn_14055 shn_14055 shn_14165 shn_14165 shn_14185 shn_14185 shn_14720 shn_14720 shn_14900 shn_14900 pal pal pgk pgk shn_15235 shn_15235 shn_15355 shn_15355 shn_15430 shn_15430 shn_15605 shn_15605 xylB xylB shn_16105 shn_16105 shn_16350 shn_16350 shn_16395 shn_16395 shn_16425 shn_16425 shn_16650 shn_16650 aroK aroK shn_18215 shn_18215 shn_18865 shn_18865 shn_18905 shn_18905 shn_18970 shn_18970 shn_19000 shn_19000 shn_19430 shn_19430 proB proB shn_19830 shn_19830 shn_19945 shn_19945 coaE coaE shn_20125 shn_20125 shn_20140 shn_20140 shn_20145 shn_20145 shn_20150 shn_20150 coaA coaA shn_20275 shn_20275 shn_20405 shn_20405 ackA ackA shn_20805 shn_20805 slyX slyX glk glk shn_21420 shn_21420 shn_21510 shn_21510 ackA-2 ackA-2 shn_22330 shn_22330
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
shn_10840Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
shn_10830ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
shn_10470Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (174 aa)
shn_10225Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (671 aa)
shn_10185Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
shn_10120Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (125 aa)
shn_09840Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
shn_098152-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
shn_09775Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (870 aa)
shn_09725AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
shn_09695Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
shn_09685PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (756 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
shn_09250Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (377 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (221 aa)
shn_08550Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
shn_08515Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
shn_08020Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
shn_07920Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. (367 aa)
shn_07770Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (344 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (257 aa)
shn_06735Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (761 aa)
shn_06565Death-on-curing family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (219 aa)
shn_05950GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa)
shn_05800Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1116 aa)
shn_11115Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
shn_057855-dehydro-2-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
shn_05695Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
shn_05610PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
shn_05600Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
shn_05560Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
shn_05405Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (508 aa)
ppkRNA degradosome polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (738 aa)
shn_05030Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (766 aa)
shn_04595Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
shn_04535Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
shn_04510Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (713 aa)
shn_04410Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (888 aa)
shn_04325Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (970 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (321 aa)
shn_04185Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1184 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa)
shn_037652-dehydro-3-deoxygalactonokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
shn_03725Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (353 aa)
shn_03640Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (326 aa)
shn_03615Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (932 aa)
shn_03200Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
mtnKS-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (423 aa)
shn_02845Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
shn_02645Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
shn_02630Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
shn_02440Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
shn_02290DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
shn_02055Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa)
shn_01905PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1230 aa)
shn_01490Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa)
shn_01485Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
shn_01470Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
shn_01260Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
shn_00930Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
shn_00795Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1166 aa)
shn_00705Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1299 aa)
shn_00660Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
shn_00520Phosphate regulon sensor histidine kinase PhoR; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
shn_00515Polyphosphate kinase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
shn_00475Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (237 aa)
shn_00415Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
shn_00395Adenylate cyclase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
shn_00350Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
shn_00115Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)
shn_11305N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
pfpPyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (404 aa)
shn_12135Ribonuclease H; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
shn_12250Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
shn_12265Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
shn_12320Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (529 aa)
shn_12770Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
shn_132902-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (497 aa)
shn_13420Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1213 aa)
shn_14055Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
shn_14165Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
shn_14185Ribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
shn_14720Glycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
shn_14900Histidine phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
palPeptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (178 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (399 aa)
shn_15235Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (479 aa)
shn_15355Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
shn_15430Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (343 aa)
shn_15605Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (771 aa)
xylBXylulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
shn_16105Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (891 aa)
shn_16350Ribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
shn_16395D-erythrulose kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
shn_16425Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (516 aa)
shn_16650Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (193 aa)
shn_18215DNA primase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
shn_18865Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
shn_18905Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0434 family. (62 aa)
shn_18970Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
shn_19000Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (424 aa)
shn_19430Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (390 aa)
shn_19830Pyridoxal kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family. (291 aa)
shn_19945Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (273 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa)
shn_20125Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (817 aa)
shn_20140PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
shn_20145Serine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
shn_20150Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
shn_20275Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
shn_20405Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (308 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (391 aa)
shn_20805Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
slyXHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SlyX family. (74 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (341 aa)
shn_21420Nucleoside/nucleotide kinase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
shn_21510Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (287 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
shn_22330Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
Your Current Organism:
Shinella sp. HZN7
NCBI taxonomy Id: 879274
Other names: S. sp. HZN7
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