STRINGSTRING
APF17809.1 APF17809.1 APF17810.1 APF17810.1 metX metX APF17812.1 APF17812.1 APF17823.1 APF17823.1 argR argR APF17825.1 APF17825.1 APF17990.1 APF17990.1 APF17991.1 APF17991.1 APF18052.1 APF18052.1 APF18053.1 APF18053.1 APF18054.1 APF18054.1 APF18056.1 APF18056.1 APF18088.1 APF18088.1 APF18108.1 APF18108.1 APF18109.1 APF18109.1 Cabys_138 Cabys_138 udk udk tdk tdk Cabys_143 Cabys_143 cysS cysS thyX thyX APF18367.1 APF18367.1 Cabys_162 Cabys_162 Cabys_166 Cabys_166 APF18457.1 APF18457.1 APF18462.1 APF18462.1 hisC hisC APF18481.1 APF18481.1 APF18482.1 APF18482.1 argC argC argB argB APF18485.1 APF18485.1 argH argH proC proC APF18547.1 APF18547.1 APF18555.1 APF18555.1 trpE trpE APF18648.1 APF18648.1 trpD trpD trpC trpC trpF trpF trpB trpB trpA trpA ahcY ahcY APF18684.1 APF18684.1 guaA guaA surE surE hisA hisA hisF hisF hisI hisI APF18868.1 APF18868.1 APF18869.1 APF18869.1 APF18870.1 APF18870.1 APF18871.1 APF18871.1 APF18874.1 APF18874.1 APF18875.1 APF18875.1 APF18880.1 APF18880.1 APF18928.1 APF18928.1 APF19014.1 APF19014.1 hisH hisH hisB hisB hisC-2 hisC-2 hisD hisD hisG hisG APF19133.1 APF19133.1 argD argD apt apt Cabys_260 Cabys_260 Cabys_261 Cabys_261 APF19380.1 APF19380.1 folD folD APF19449.1 APF19449.1 APF19450.1 APF19450.1 APF19475.1 APF19475.1 aroE aroE APF19520.1 APF19520.1 gmk gmk APF19544.1 APF19544.1 APF19589.1 APF19589.1 APF19590.1 APF19590.1 APF19621.1 APF19621.1 APF19667.1 APF19667.1 APF19677.1 APF19677.1 APF19718.1 APF19718.1 APF19753.1 APF19753.1 APF19895.1 APF19895.1 argC-2 argC-2 APF19899.1 APF19899.1 argD-2 argD-2 APF19908.1 APF19908.1 pyrD pyrD pyrI pyrI pyrB pyrB APF19912.1 APF19912.1 pyrE pyrE APF19914.1 APF19914.1 purF purF purN purN purD purD APF19919.1 APF19919.1 purC purC purH purH APF19923.1 APF19923.1 APF19924.1 APF19924.1 purL purL APF19926.1 APF19926.1 purA purA APF19928.1 APF19928.1 APF19945.1 APF19945.1 APF19946.1 APF19946.1 APF19947.1 APF19947.1 leuA leuA leuB leuB ilvC ilvC APF19951.1 APF19951.1 APF19952.1 APF19952.1 ilvD ilvD APF19981.1 APF19981.1 APF20003.1 APF20003.1 APF20013.1 APF20013.1 serC serC APF20063.1 APF20063.1 thrB thrB APF20065.1 APF20065.1 argD-3 argD-3 APF20083.1 APF20083.1 APF20217.1 APF20217.1 Cabys_352 Cabys_352 Cabys_353 Cabys_353 APF20358.1 APF20358.1 ftsH-2 ftsH-2 APF20487.1 APF20487.1 aroQ aroQ aroB aroB aroK aroK aroC aroC APF20530.1 APF20530.1 APF20574.1 APF20574.1 carA carA metK metK upp upp APF20656.1 APF20656.1 APF20663.1 APF20663.1 tmk tmk glyA glyA Cabys_590 Cabys_590 Cabys_656 Cabys_656 lysA lysA Cabys_800 Cabys_800 dapF dapF Cabys_937 Cabys_937 Cabys_985 Cabys_985 Cabys_986 Cabys_986 Cabys_989 Cabys_989
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APF17809.1Hypothetical protein. (37 aa)
APF17810.1O-acetylhomoserine sulfhydrylase. (433 aa)
metXmetX homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (372 aa)
APF17812.1Aspartate kinase; Belongs to the aspartokinase family. (456 aa)
APF17823.1Tetratricopeptide repeat-containing protein. (108 aa)
argRargR transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (148 aa)
APF17825.1Radical SAM-linked protein/radical SAM family uncharacterized protein. (874 aa)
APF17990.1dGTPase; Belongs to the dGTPase family. Type 2 subfamily. (392 aa)
APF17991.1Succinyl-diaminopimelate desuccinylase. (412 aa)
APF18052.15-methyltetrahydrofolate--homocysteine methyltransferase. (296 aa)
APF18053.1Methanogenic corrinoid protein MtbC1. (221 aa)
APF18054.1Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family. (284 aa)
APF18056.1Sugar kinase of the NBD/HSP70 family, may containing an N-terminal HTH domain. (389 aa)
APF18088.1Methionine-gamma-lyase. (394 aa)
APF18108.1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)
APF18109.1Serine O-acetyltransferase. (281 aa)
Cabys_138Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (129 aa)
udkUdk uridine kinase. (214 aa)
tdkTdk thymidine kinase. (193 aa)
Cabys_143Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)
cysScysS cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (484 aa)
thyXthyX thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (308 aa)
APF18367.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (276 aa)
Cabys_162solute:Na+ symporter, SSS family; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (508 aa)
Cabys_166dCMP deaminase. (148 aa)
APF18457.1Aspartate semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (354 aa)
APF18462.1Deoxyadenosine/deoxycytidine kinase. (215 aa)
hisChisC histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
APF18481.1L-amino acid N-acyltransferase YncA. (202 aa)
APF18482.1Argininosuccinate synthase. (402 aa)
argCargC N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (321 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (256 aa)
APF18485.1Acetylornithine deacetylase. (357 aa)
argHargH argininosuccinate lyase. (448 aa)
proCproC pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
APF18547.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (562 aa)
APF18555.1Methionine-gamma-lyase. (399 aa)
trpEAnthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (494 aa)
APF18648.1Anthranilate synthase component 2/para-aminobenzoate synthetase component 2. (195 aa)
trpDtrpD anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa)
trpCtrpC indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa)
trpFtrpF phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (217 aa)
trpBtrpB tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa)
trpAtrpA tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
ahcYahcY adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (418 aa)
APF18684.1Aminotransferase class-III; acetylornithine/N-succinyldiaminopimelate aminotransferase/acetylornithine/LysW-gamma-L-lysine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (493 aa)
guaAguaA GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (522 aa)
surEsurE 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
hisAhisA 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase. (247 aa)
hisFhisF cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisIhisI phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (197 aa)
APF18868.1Putative selenium metabolism hydrolase. (403 aa)
APF18869.1N-acetylornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (325 aa)
APF18870.1Threonine synthase. (425 aa)
APF18871.1Cysteine synthase. (490 aa)
APF18874.1Allantoinase. (485 aa)
APF18875.1Putative selenium metabolism protein SsnA. (446 aa)
APF18880.1Selenate reductase, Fe-S subunit. (1075 aa)
APF18928.1Cytidine deaminase. (126 aa)
APF19014.1Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. (610 aa)
hisHhisH glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (194 aa)
hisBImidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (363 aa)
hisC-2hisC histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
hisDhisD histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa)
hisGhisG ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (284 aa)
APF19133.1GAF domain-containing protein. (163 aa)
argDargD acetylornithine aminotransferase/acetylornithine/N-succinyldiaminopimelate aminotransferase. (393 aa)
aptApt adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa)
Cabys_260GMP synthase (glutamine-hydrolysing). (233 aa)
Cabys_261Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate. (330 aa)
APF19380.1Homoaconitate hydratase family protein/3-isopropylmalate dehydratase, large subunit/3-isopropylmalate dehydratase, small subunit. (607 aa)
folDfolD methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
APF19449.1Chorismate binding enzyme. (433 aa)
APF19450.1Anthranilate phosphoribosyltransferase/anthranilate synthase component 2. (197 aa)
APF19475.12',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. (565 aa)
aroEaroE shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
APF19520.13-phosphoshikimate 1-carboxyvinyltransferase. (420 aa)
gmkGmk guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (186 aa)
APF19544.1Chorismate mutase. (101 aa)
APF19589.1Prephenate dehydrogenase. (348 aa)
APF19590.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (344 aa)
APF19621.1Delta-1-pyrroline-5-carboxylate dehydrogenase. (543 aa)
APF19667.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)
APF19677.1Cystathionine beta-synthase. (317 aa)
APF19718.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa)
APF19753.1NADPH-dependent glutamate synthase beta chain. (445 aa)
APF19895.1Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (383 aa)
argC-2argC N-acetyl-gamma-glutamyl-phosphate reductase; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (348 aa)
APF19899.1acetylglutamate/LysW-gamma-L-alpha-aminoadipate kinase. (263 aa)
argD-2argD acetylornithine aminotransferase apoenzyme. (389 aa)
APF19908.1Dihydroorotate dehydrogenase electron transfer subunit. (260 aa)
pyrDpyrD dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (305 aa)
pyrIpyrI aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (159 aa)
pyrBpyrB aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
APF19912.1Orotidine-5'-phosphate decarboxylase. (228 aa)
pyrEpyrE orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)
APF19914.1Dihydroorotase. (424 aa)
purFpurF amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (477 aa)
purNpurN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa)
purDpurD phosphoribosylamine--glycine ligase; Belongs to the GARS family. (415 aa)
APF19919.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa)
purCpurC phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (461 aa)
purHpurH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. (537 aa)
APF19923.1Phosphoribosylformylglycinamidine synthase. (272 aa)
APF19924.1GMP synthase (glutamine-hydrolysing). (233 aa)
purLpurL phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (997 aa)
APF19926.1Phosphoribosylformylglycinamidine cyclo-ligase. (380 aa)
purApurA Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (406 aa)
APF19928.1IMP dehydrogenase. (498 aa)
APF19945.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (536 aa)
APF19946.13-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Belongs to the LeuD family. (217 aa)
APF19947.13-isopropylmalate dehydratase, large subunit; Belongs to the aconitase/IPM isomerase family. (432 aa)
leuAleuA 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (521 aa)
leuBleuB 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (365 aa)
ilvCilvC ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
APF19951.1Acetolactate synthase, small subunit. (170 aa)
APF19952.1Acetolactate synthase, large subunit. (572 aa)
ilvDilvD dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (561 aa)
APF19981.1ACT domain-containing protein. (154 aa)
APF20003.1Homoserine dehydrogenase. (342 aa)
APF20013.1Homoserine dehydrogenase. (348 aa)
serCserC phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
APF20063.1Aspartate kinase; Belongs to the aspartokinase family. (467 aa)
thrBthrB homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (319 aa)
APF20065.1L-threonine synthase. (433 aa)
argD-3argD ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
APF20083.13-oxoacyl-(acyl-carrier protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
APF20217.1Carbamate kinase; Belongs to the carbamate kinase family. (317 aa)
Cabys_352Hypothetical protein. (207 aa)
Cabys_353Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (825 aa)
APF20358.1Pyrimidine-nucleoside phosphorylase. (439 aa)
ftsH-2ftsH membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (694 aa)
APF20487.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa)
aroQaroQ 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa)
aroBaroB 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa)
aroKaroK shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa)
aroCaroC chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (387 aa)
APF20530.15,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. (317 aa)
APF20574.1Carbamoyl-phosphate synthase large subunit. (1065 aa)
carAcarA carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (358 aa)
metKmetK methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (378 aa)
uppUpp uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
APF20656.1Homoserine dehydrogenase. (436 aa)
APF20663.12',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family; Belongs to the 5'-nucleotidase family. (534 aa)
tmkTmk thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
glyAglyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
Cabys_590L-proline dehydrogenase. (302 aa)
Cabys_656Branched-chain amino acid aminotransferase. (343 aa)
lysAlysA diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
Cabys_800Sulfide dehydrogenase (flavoprotein) subunit SudB. (288 aa)
dapFdapF diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (273 aa)
Cabys_937Deoxyadenosine/deoxycytidine kinase. (217 aa)
Cabys_985Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (469 aa)
Cabys_986Nicotinamidase/pyrazinamidase. (205 aa)
Cabys_989Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1240 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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