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APF17990.1 APF17990.1 Cabys_138 Cabys_138 udk udk tdk tdk Cabys_143 Cabys_143 APF18367.1 APF18367.1 Cabys_166 Cabys_166 APF18462.1 APF18462.1 guaA guaA surE surE APF18868.1 APF18868.1 APF18874.1 APF18874.1 APF18875.1 APF18875.1 APF18880.1 APF18880.1 APF18928.1 APF18928.1 apt apt Cabys_260 Cabys_260 Cabys_261 Cabys_261 APF19475.1 APF19475.1 gmk gmk APF19753.1 APF19753.1 APF19908.1 APF19908.1 pyrD pyrD pyrI pyrI pyrB pyrB APF19912.1 APF19912.1 pyrE pyrE APF19914.1 APF19914.1 purF purF purN purN purD purD APF19919.1 APF19919.1 purC purC purH purH APF19923.1 APF19923.1 APF19924.1 APF19924.1 purL purL APF19926.1 APF19926.1 purA purA APF19928.1 APF19928.1 Cabys_352 Cabys_352 Cabys_353 Cabys_353 APF20358.1 APF20358.1 ftsH-2 ftsH-2 APF20487.1 APF20487.1 APF20574.1 APF20574.1 carA carA upp upp APF20663.1 APF20663.1 tmk tmk Cabys_800 Cabys_800 Cabys_937 Cabys_937 Cabys_985 Cabys_985 Cabys_986 Cabys_986
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
APF17990.1dGTPase; Belongs to the dGTPase family. Type 2 subfamily. (392 aa)
Cabys_138Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (129 aa)
udkUdk uridine kinase. (214 aa)
tdkTdk thymidine kinase. (193 aa)
Cabys_143Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)
APF18367.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (276 aa)
Cabys_166dCMP deaminase. (148 aa)
APF18462.1Deoxyadenosine/deoxycytidine kinase. (215 aa)
guaAguaA GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (522 aa)
surEsurE 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
APF18868.1Putative selenium metabolism hydrolase. (403 aa)
APF18874.1Allantoinase. (485 aa)
APF18875.1Putative selenium metabolism protein SsnA. (446 aa)
APF18880.1Selenate reductase, Fe-S subunit. (1075 aa)
APF18928.1Cytidine deaminase. (126 aa)
aptApt adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa)
Cabys_260GMP synthase (glutamine-hydrolysing). (233 aa)
Cabys_261Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate. (330 aa)
APF19475.12',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. (565 aa)
gmkGmk guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (186 aa)
APF19753.1NADPH-dependent glutamate synthase beta chain. (445 aa)
APF19908.1Dihydroorotate dehydrogenase electron transfer subunit. (260 aa)
pyrDpyrD dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (305 aa)
pyrIpyrI aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (159 aa)
pyrBpyrB aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
APF19912.1Orotidine-5'-phosphate decarboxylase. (228 aa)
pyrEpyrE orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)
APF19914.1Dihydroorotase. (424 aa)
purFpurF amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (477 aa)
purNpurN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa)
purDpurD phosphoribosylamine--glycine ligase; Belongs to the GARS family. (415 aa)
APF19919.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa)
purCpurC phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (461 aa)
purHpurH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. (537 aa)
APF19923.1Phosphoribosylformylglycinamidine synthase. (272 aa)
APF19924.1GMP synthase (glutamine-hydrolysing). (233 aa)
purLpurL phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (997 aa)
APF19926.1Phosphoribosylformylglycinamidine cyclo-ligase. (380 aa)
purApurA Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (406 aa)
APF19928.1IMP dehydrogenase. (498 aa)
Cabys_352Hypothetical protein. (207 aa)
Cabys_353Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (825 aa)
APF20358.1Pyrimidine-nucleoside phosphorylase. (439 aa)
ftsH-2ftsH membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (694 aa)
APF20487.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa)
APF20574.1Carbamoyl-phosphate synthase large subunit. (1065 aa)
carAcarA carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (358 aa)
uppUpp uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
APF20663.12',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family; Belongs to the 5'-nucleotidase family. (534 aa)
tmkTmk thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
Cabys_800Sulfide dehydrogenase (flavoprotein) subunit SudB. (288 aa)
Cabys_937Deoxyadenosine/deoxycytidine kinase. (217 aa)
Cabys_985Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (469 aa)
Cabys_986Nicotinamidase/pyrazinamidase. (205 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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