STRINGSTRING
Cabys_115 Cabys_115 APF17904.1 APF17904.1 APF17907.1 APF17907.1 APF18152.1 APF18152.1 APF18301.1 APF18301.1 APF18452.1 APF18452.1 APF18453.1 APF18453.1 fumC fumC Cabys_172 Cabys_172 Cabys_173 Cabys_173 APF18488.1 APF18488.1 APF18489.1 APF18489.1 APF18526.1 APF18526.1 APF18640.1 APF18640.1 APF18660.1 APF18660.1 APF18661.1 APF18661.1 gcvPA gcvPA gcvPB gcvPB glmS glmS APF18802.1 APF18802.1 APF18831.1 APF18831.1 gcvH gcvH Cabys_22 Cabys_22 APF19000.1 APF19000.1 APF19062.1 APF19062.1 gcvT gcvT APF19334.1 APF19334.1 APF19335.1 APF19335.1 Cabys_262 Cabys_262 APF19382.1 APF19382.1 pckA pckA lipA lipA sucD sucD sucC sucC APF20253.1 APF20253.1 APF20254.1 APF20254.1 APF20528.1 APF20528.1 APF20544.1 APF20544.1 APF20545.1 APF20545.1 APF20546.1 APF20546.1 mdh mdh APF20818.1 APF20818.1 APF20819.1 APF20819.1 APF20820.1 APF20820.1 Cabys_704 Cabys_704 Cabys_78 Cabys_78 Cabys_801 Cabys_801 Cabys_82 Cabys_82
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cabys_115Aspartate aminotransferase. (399 aa)
APF17904.1Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (453 aa)
APF17907.1Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (428 aa)
APF18152.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa)
APF18301.1Glutamate dehydrogenase (NAD/NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (413 aa)
APF18452.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (610 aa)
APF18453.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (345 aa)
fumCfumC fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
Cabys_172Fumarate hydratase, class I. (194 aa)
Cabys_173Fumarate hydratase, class I. (289 aa)
APF18488.1Glutamate synthase (NADH) large subunit. (1504 aa)
APF18489.1Glutamate synthase (NADH) small subunit. (471 aa)
APF18526.1Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (743 aa)
APF18640.1Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase. (453 aa)
APF18660.12-oxoglutarate dehydrogenase E1 component. (932 aa)
APF18661.12-oxoglutarate dehydrogenase E2 component. (411 aa)
gcvPAgcvPA glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (429 aa)
gcvPBgcvPB glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
glmSglmS glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
APF18802.1L-glutamine synthetase. (728 aa)
APF18831.1Glutamine synthetase. (457 aa)
gcvHgcvH glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
Cabys_22Citrate synthase; Belongs to the citrate synthase family. (435 aa)
APF19000.1Lipoate-protein ligase A. (333 aa)
APF19062.1Allosteric NADP-dependent malic enzyme. (748 aa)
gcvTgcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (358 aa)
APF19334.1Phosphoenolpyruvate carboxykinase (ATP). (613 aa)
APF19335.1Aspartate/methionine/tyrosine aminotransferase. (782 aa)
Cabys_262Pyruvate-ferredoxin/flavodoxin oxidoreductase. (1192 aa)
APF19382.13-isopropylmalate dehydrogenase. (395 aa)
pckApckA phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
lipAlipA lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (320 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCsucC succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
APF20253.12-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). (430 aa)
APF20254.12-oxoisovalerate dehydrogenase E1 component. (678 aa)
APF20528.1Isocitrate dehydrogenase (NAD+). (341 aa)
APF20544.1Dihydrolipoamide dehydrogenase. (475 aa)
APF20545.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (442 aa)
APF20546.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
mdhMdh malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (318 aa)
APF20818.1Succinate dehydrogenase subunit C. (231 aa)
APF20819.1Succinate dehydrogenase subunit A. (636 aa)
APF20820.1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (251 aa)
Cabys_704Malate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. (316 aa)
Cabys_78Dihydrolipoamide dehydrogenase. (463 aa)
Cabys_801Sulfide dehydrogenase (flavoprotein) subunit SudA. (475 aa)
Cabys_82Aconitase. (755 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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