node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APF19014.1 | fmt | Cabys_2265 | Cabys_2683 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.919 |
APF19014.1 | gcvT | Cabys_2265 | Cabys_2475 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.936 |
APF19014.1 | glyA | Cabys_2265 | Cabys_4203 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
APF19014.1 | purH | Cabys_2265 | Cabys_3174 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | purH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.910 |
APF19014.1 | purN | Cabys_2265 | Cabys_3169 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | purN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.911 |
fmt | APF19014.1 | Cabys_2683 | Cabys_2265 | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | 0.919 |
fmt | gcvT | Cabys_2683 | Cabys_2475 | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.929 |
fmt | glyA | Cabys_2683 | Cabys_4203 | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.925 |
fmt | purH | Cabys_2683 | Cabys_3174 | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | purH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.448 |
fmt | purN | Cabys_2683 | Cabys_3169 | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | purN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.931 |
gcvT | APF19014.1 | Cabys_2475 | Cabys_2265 | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | 0.936 |
gcvT | fmt | Cabys_2475 | Cabys_2683 | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.929 |
gcvT | glyA | Cabys_2475 | Cabys_4203 | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
gcvT | purH | Cabys_2475 | Cabys_3174 | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | purH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.941 |
gcvT | purN | Cabys_2475 | Cabys_3169 | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | purN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.931 |
glyA | APF19014.1 | Cabys_4203 | Cabys_2265 | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. | 0.924 |
glyA | fmt | Cabys_4203 | Cabys_2683 | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.925 |
glyA | gcvT | Cabys_4203 | Cabys_2475 | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | gcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.997 |
glyA | purH | Cabys_4203 | Cabys_3174 | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | purH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.990 |
glyA | purN | Cabys_4203 | Cabys_3169 | glyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | purN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.972 |