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| | APF17764.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | pyrH | pyrH uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | APF17871.1 | Hypothetical protein. (317 aa) |
| | APF17892.1 | RNA polymerase sigma factor for flagellar operon FliA; Belongs to the sigma-70 factor family. (252 aa) |
| | APF17927.1 | Sigma 54 modulation protein / S30EA ribosomal protein. (319 aa) |
| | APF17928.1 | S-layer domain-containing protein. (359 aa) |
| | APF17937.1 | RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (281 aa) |
| | kdsB | kdsB 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa) |
| | pyrG | pyrG CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa) |
| | Cabys_12 | RNA polymerase sigma-70 factor, ECF subfamily. (193 aa) |
| | priA | priA replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (817 aa) |
| | APF18037.1 | Ca-activated chloride channel family protein. (331 aa) |
| | APF18038.1 | Ca-activated chloride channel family protein. (345 aa) |
| | APF18055.1 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (340 aa) |
| | queC | queC 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa) |
| | queF | queF 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (120 aa) |
| | queE | queE 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (217 aa) |
| | APF18082.1 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (121 aa) |
| | udk | Udk uridine kinase. (214 aa) |
| | tdk | Tdk thymidine kinase. (193 aa) |
| | queA | queA S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (343 aa) |
| | fliI/YscN | Type III secretion system ATPase, FliI/YscN. (434 aa) |
| | APF18242.1 | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Belongs to the sigma-70 factor family. (257 aa) |
| | thyX | thyX thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (308 aa) |
| | APF18326.1 | WbqC-like protein family protein. (220 aa) |
| | dnaG | dnaG DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (607 aa) |
| | Cabys_165 | 7, 8-dihydropterin-6-yl-methyl-4-(beta-D- ribofuranosyl)aminobenzene 5'-phosphate synthase. (278 aa) |
| | selA | selA L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (468 aa) |
| | APF18442.1 | Putative conserved protein YegL, contains vWA domain of TerY type. (661 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa) |
| | APF18447.1 | Putative ATPase. (415 aa) |
| | APF18460.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa) |
| | APF18461.1 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase/dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (160 aa) |
| | APF18462.1 | Deoxyadenosine/deoxycytidine kinase. (215 aa) |
| | dinB | dinB DNA polymerase-4/DNA polymerase IV (DinB-like DNA polymerase); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (385 aa) |
| | proC | proC pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa) |
| | APF18589.1 | RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (156 aa) |
| | APF18595.1 | Uridine kinase. (212 aa) |
| | Cabys_186 | RNA polymerase sigma-70 factor, ECF subfamily. (200 aa) |
| | Cabys_187 | DNA polymerase III, delta subunit. (331 aa) |
| | coaD | coaD Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa) |
| | trpD | trpD anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | trpC | trpC indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa) |
| | trpF | trpF phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (217 aa) |
| | trpB | trpB tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa) |
| | trpA | trpA tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa) |
| | pdxS | pdxS pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (295 aa) |
| | APF18683.1 | Pyridoxal phosphate synthase yaaE subunit. (190 aa) |
| | guaA | guaA GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (522 aa) |
| | accD | accD acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | Cabys_2 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (373 aa) |
| | moaA | moaA cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (337 aa) |
| | APF18758.1 | Molybdenum cofactor biosynthesis protein MoaC. (310 aa) |
| | APF18759.1 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (404 aa) |
| | nadE | nadE NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (320 aa) |
| | thiI | thiI thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (387 aa) |
| | APF18789.1 | Molybdenum cofactor biosynthesis enzyme MoaA. (500 aa) |
| | APF18851.1 | NTPase. (154 aa) |
| | APF18874.1 | Allantoinase. (485 aa) |
| | ndk | Ndk nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | satD | SatD family (SatD). (215 aa) |
| | APF19027.1 | 7, 8-dihydropterin-6-yl-methyl-4-(beta-D- ribofuranosyl)aminobenzene 5'-phosphate synthase. (213 aa) |
| | coaE | coaE dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (218 aa) |
| | APF19096.1 | Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (336 aa) |
| | APF19098.1 | Creatinine amidohydrolase. (264 aa) |
| | APF19102.1 | Reductive dehalogenase. (445 aa) |
| | APF19121.1 | DNA polymerase-3 subunit alpha. (1064 aa) |
| | apt | Apt adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa) |
| | APF19187.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (522 aa) |
| | nadA | nadA quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (347 aa) |
| | APF19189.1 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. (273 aa) |
| | APF19204.1 | Transcription elongation factor/antiterminator RfaH. (173 aa) |
| | APF19218.1 | UDP-glucose dehydrogenase. (445 aa) |
| | comB | comB 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (241 aa) |
| | APF19238.1 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (289 aa) |
| | nusA | nusA NusA antitermination factor; Participates in both transcription termination and antitermination. (429 aa) |
| | cmk | Cmk cytidylate kinase. (229 aa) |
| | rho | Rho transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (360 aa) |
| | pdxA | pdxA 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (333 aa) |
| | APF19298.1 | RNA polymerase, sigma 54 subunit, RpoN/SigL. (492 aa) |
| | APF19344.1 | D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (159 aa) |
| | rfaE | rfaE bifunctional protein, domain I. (334 aa) |
| | Cabys_260 | GMP synthase (glutamine-hydrolysing). (233 aa) |
| | Cabys_261 | Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate. (330 aa) |
| | APF19374.1 | Cobalt/nickel transport system permease protein. (198 aa) |
| | folD | folD methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa) |
| | hemL | hemL glutamate-1-semialdehyde 2,1-aminomutase. (427 aa) |
| | APF19419.1 | Porphobilinogen synthase; Belongs to the ALAD family. (325 aa) |
| | APF19420.1 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (453 aa) |
| | hemH | hemH ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (335 aa) |
| | APF19422.1 | Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (464 aa) |
| | hemE | hemE uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa) |
| | APF19425.1 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (263 aa) |
| | hemC | hemC hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (313 aa) |
| | hemA | hemA glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (429 aa) |
| | tgt | Tgt queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to fo [...] (377 aa) |
| | nadK | nadK NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (310 aa) |
| | APF19455.1 | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (236 aa) |
| | APF19499.1 | 8-amino-7-oxononanoate synthase. (396 aa) |
| | APF19525.1 | Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (477 aa) |
| | APF19528.1 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. (353 aa) |
| | gmk | Gmk guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (186 aa) |
| | APF19538.1 | DNA polymerase III catalytic subunit, DnaE type. (1158 aa) |
| | nadD | nadD nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa) |
| | coaX | coaX pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (259 aa) |
| | APF19614.1 | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa) |
| | murA | murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | APF19726.1 | Cell surface protein SprA. (2025 aa) |
| | dinG | ATP-dependent DNA helicase DinG; 3'-5' exonuclease. (995 aa) |
| | nusB | nusB NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (150 aa) |
| | acsA | acsA acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (633 aa) |
| | atpC | atpC ATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | atpD | atpD ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (465 aa) |
| | atpG | atpG ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (289 aa) |
| | atpA | atpA ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (506 aa) |
| | atpH | atpH ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa) |
| | atpF | atpF ATP synthase F0 subcomplex B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | aTP | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa) |
| | atpB | atpB ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (282 aa) |
| | Cabys_308 | Radical SAM additional 4Fe4S-binding SPASM domain-containing protein. (386 aa) |
| | APF19850.1 | Cytochrome c oxidase assembly protein subunit 15. (308 aa) |
| | ctaB | ctaB protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (287 aa) |
| | APF19872.1 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (183 aa) |
| | APF19908.1 | Dihydroorotate dehydrogenase electron transfer subunit. (260 aa) |
| | pyrD | pyrD dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (305 aa) |
| | pyrI | pyrI aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (159 aa) |
| | pyrB | pyrB aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | APF19912.1 | Orotidine-5'-phosphate decarboxylase. (228 aa) |
| | pyrE | pyrE orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa) |
| | APF19914.1 | Dihydroorotase. (424 aa) |
| | purF | purF amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (477 aa) |
| | purN | purN formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (198 aa) |
| | purD | purD phosphoribosylamine--glycine ligase; Belongs to the GARS family. (415 aa) |
| | APF19919.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa) |
| | purC | purC phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (461 aa) |
| | purH | purH IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. (537 aa) |
| | APF19923.1 | Phosphoribosylformylglycinamidine synthase. (272 aa) |
| | APF19924.1 | GMP synthase (glutamine-hydrolysing). (233 aa) |
| | purL | purL phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (997 aa) |
| | APF19926.1 | Phosphoribosylformylglycinamidine cyclo-ligase. (380 aa) |
| | purA | purA Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (406 aa) |
| | APF19975.1 | Sulfite reductase, subunit B. (279 aa) |
| | serC | serC phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | dnaX | DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (522 aa) |
| | lipA | lipA lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (320 aa) |
| | APF20074.1 | Creatinine amidohydrolase. (246 aa) |
| | APF20146.1 | UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase. (372 aa) |
| | APF20147.1 | dTDP-4-dehydrorhamnose 3,5-epimerase. (149 aa) |
| | APF20158.1 | Transferase hexapeptide (six repeat-containing protein). (247 aa) |
| | APF20181.1 | UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase. (207 aa) |
| | ackA | ackA acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | ndk-2 | Ndk nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (144 aa) |
| | Cabys_354 | cob(I)yrinic acid a,c-diamide adenosyltransferase. (176 aa) |
| | Cabys_356 | Adenylate cyclase, class 3. (350 aa) |
| | queG | queG epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (317 aa) |
| | APF20430.1 | Biotin synthase. (351 aa) |
| | APF20454.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (297 aa) |
| | accA | accA acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa) |
| | APF20464.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (289 aa) |
| | dacA | Diadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (267 aa) |
| | APF20482.1 | Dihydropteroate synthase. (362 aa) |
| | APF20487.1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa) |
| | APF20491.1 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase. (255 aa) |
| | Cabys_380 | RNA polymerase, sigma-24 subunit, RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa) |
| | carA | carA carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (358 aa) |
| | APF20621.1 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (365 aa) |
| | APF20622.1 | Riboflavin synthase alpha chain. (215 aa) |
| | ribBA | ribBA GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (408 aa) |
| | ribH | ribH 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (153 aa) |
| | upp | Upp uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | APF20682.1 | Competence/damage-inducible protein cinA; Belongs to the CinA family. (415 aa) |
| | APF20686.1 | Protein of unknown function (DUF2905). (69 aa) |
| | APF20690.1 | RNA polymerase sigma-70 factor, ECF subfamily. (193 aa) |
| | nadE-2 | nadE NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (275 aa) |
| | tmk | Tmk thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa) |
| | APF20721.1 | Thiamine diphosphokinase. (210 aa) |
| | APF20726.1 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (141 aa) |
| | APF20727.1 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (138 aa) |
| | folE | folE GTP cyclohydrolase I. (190 aa) |
| | trpB-2 | trpB tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (454 aa) |
| | APF20753.1 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (348 aa) |
| | satD-2 | SatD family (SatD). (214 aa) |
| | Cabys_549 | RNA polymerase sigma-70 factor, ECF subfamily. (202 aa) |
| | Cabys_554 | Radical SAM additional 4Fe4S-binding SPASM domain-containing protein. (361 aa) |
| | Cabys_587 | 4a-hydroxytetrahydrobiopterin dehydratase. (93 aa) |
| | Cabys_631 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (386 aa) |
| | adk | Adk Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) |
| | Cabys_686 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (431 aa) |
| | rho-2 | Rho transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (416 aa) |
| | Cabys_709 | N-terminal double-transmembrane domain-containing protein. (682 aa) |
| | Cabys_714 | DNA polymerase-3 subunit delta'. (366 aa) |
| | serS | serS seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (467 aa) |
| | Cabys_739 | DNA polymerase (family 10). (578 aa) |
| | Cabys_74 | DNA polymerase III, chi subunit. (152 aa) |
| | Cabys_792 | Phosphopantothenoylcysteine decarboxylase. (181 aa) |
| | Cabys_800 | Sulfide dehydrogenase (flavoprotein) subunit SudB. (288 aa) |
| | dinB-2 | dinB DNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (406 aa) |
| | mobA | mobA molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (208 aa) |
| | Cabys_811 | Molybdopterin guanine dinucleotide biosynthesis accessory protein MobB. (164 aa) |
| | Cabys_816 | 16S rRNA (cytosine967-C5)-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (450 aa) |
| | nusG | nusG transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (171 aa) |
| | rpoB | rpoB DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1258 aa) |
| | rpoC | rpoC DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1429 aa) |
| | rpoA | rpoA DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa) |
| | Cabys_937 | Deoxyadenosine/deoxycytidine kinase. (217 aa) |
| | Cabys_958 | Radical SAM additional 4Fe4S-binding SPASM domain-containing protein. (361 aa) |
| | Cabys_985 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (469 aa) |
