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| | APF19430.1 | Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (59 aa) |
| | rplU | rplU large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (125 aa) |
| | rpmA | rpmA large subunit ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (87 aa) |
| | rplM | rplM LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (146 aa) |
| | rpsI | rpsI SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (111 aa) |
| | rpsB | rpsB SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (277 aa) |
| | tsf | Tsf translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (198 aa) |
| | frr | Frr ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (186 aa) |
| | gatC | gatC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (97 aa) |
| | rplY | rplY large subunit ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (213 aa) |
| | pth | Pth peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (167 aa) |
| | rpsF | rpsF SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (170 aa) |
| | rpsR | rpsR SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rplI | rplI LSU ribosomal protein L9P; Binds to the 23S rRNA. (147 aa) |
| | mbtH | MbtH protein. (78 aa) |
| | hutU | hutU urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (675 aa) |
| | gltX | gltX glutamyl-tRNA synthetase/nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa) |
| | cysS | cysS cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (484 aa) |
| | rpmB | rpmB LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. (65 aa) |
| | gatA | gatA aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (472 aa) |
| | gatB | gatB aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (479 aa) |
| | rpsU | rpsU SSU ribosomal protein S21P; Belongs to the bacterial ribosomal protein bS21 family. (65 aa) |
| | ileS | ileS Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1095 aa) |
| | Cabys_163 | Peptidase S46; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. (710 aa) |
| | glyQS | glyQS glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (436 aa) |
| | panD | panD L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (123 aa) |
| | selA | selA L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (468 aa) |
| | APF18459.1 | Peptidase S46; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. (713 aa) |
| | APF18461.1 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase/dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (160 aa) |
| | glnS | glnS glutaminyl-tRNA synthetase. (562 aa) |
| | APF18686.1 | Initiation factor 2 subunit family protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (296 aa) |
| | accD | accD acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa) |
| | leuS | leuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (877 aa) |
| | selB | Selenocysteine-specific translation elongation factor SelB. (637 aa) |
| | APF19014.1 | Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase. (610 aa) |
| | APF19138.1 | hydroxymethylglutaryl-CoA synthase. (354 aa) |
| | asnS | asnS asparaginyl-tRNA synthetase. (431 aa) |
| | rpsO | rpsO SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | infB | infB bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (928 aa) |
| | APF19277.1 | SSU ribosomal protein S1P. (688 aa) |
| | APF19283.1 | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (325 aa) |
| | nanE | nanE N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (235 aa) |
| | APF19349.1 | Gamma-glutamyltransferase 1 Threonine peptidase, MEROPS family T03. (561 aa) |
| | def | Def peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (166 aa) |
| | APF19378.1 | Citrate lyase subunit alpha / citrate CoA-transferase. (520 aa) |
| | pheT | pheT phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (792 aa) |
| | pheS | pheS phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (335 aa) |
| | rplT | rplT LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (115 aa) |
| | rpmI | rpmI LSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | infC | infC translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (168 aa) |
| | thrS | thrS threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (639 aa) |
| | fmt | Fmt methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa) |
| | APF19499.1 | 8-amino-7-oxononanoate synthase. (396 aa) |
| | proS | proS prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (476 aa) |
| | APF19528.1 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. (353 aa) |
| | APF19531.1 | Putative component of the ribosome quality control (RQC) complex, YloA/Tae2 family; Contains fibronectin-binding (FbpA) and DUF814 domains. (555 aa) |
| | efp | Efp translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (188 aa) |
| | APF19668.1 | Protein of unknown function (DUF814). (124 aa) |
| | hutH | hutH histidine ammonia-lyase. (512 aa) |
| | APF19752.1 | Translation initiation factor 1 (eIF-1/SUI1). (106 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (584 aa) |
| | acsA | acsA acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (633 aa) |
| | APF19822.1 | Dipeptidase D. (484 aa) |
| | APF19857.1 | Hypothetical protein. (392 aa) |
| | APF19892.1 | Histidine ammonia-lyase. (507 aa) |
| | APF19896.1 | L-2-aminoadipate N-acetyltransferase; Belongs to the RimK family. (282 aa) |
| | APF19942.1 | Peptidase T, Metallo peptidase, MEROPS family M20B; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (416 aa) |
| | Cabys_335 | Translation elongation factor 2 (EF-2/EF-G). (689 aa) |
| | tyrS | tyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa) |
| | hutI | hutI imidazolonepropionase. (410 aa) |
| | APF20140.1 | Glutathione synthase/RimK-type ligase, ATP-grasp superfamily. (345 aa) |
| | ackA | ackA acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | APF20371.1 | Hypothetical protein. (522 aa) |
| | APF20430.1 | Biotin synthase. (351 aa) |
| | accA | accA acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa) |
| | lysS | lysS lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (497 aa) |
| | prfB | prfB bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (356 aa) |
| | APF20482.1 | Dihydropteroate synthase. (362 aa) |
| | APF20589.1 | Diphosphomevalonate decarboxylase. (328 aa) |
| | alaS | alaS alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (870 aa) |
| | Cabys_399 | alanyl-tRNA synthetase. (391 aa) |
| | hisS | hisS histidyl-tRNA synthetase. (421 aa) |
| | rpmH | rpmH large subunit ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (52 aa) |
| | panB | panB ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa) |
| | panC | panC pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | argS | argS arginyl-tRNA synthetase. (544 aa) |
| | valS | valS valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (896 aa) |
| | lepA | lepA GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (601 aa) |
| | Cabys_630 | Signal peptidase I Serine peptidase, MEROPS family S26A; Belongs to the peptidase S26 family. (238 aa) |
| | gltX-2 | gltX glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | rpmE | rpmE LSU ribosomal protein L31P; Binds the 23S rRNA. (66 aa) |
| | prfA | prfA bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa) |
| | serS | serS seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (467 aa) |
| | Cabys_727 | B3/B4 domain-containing protein (DNA/RNA-binding domain of Phe-tRNA-synthetase). (223 aa) |
| | smpB | smpB SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] (153 aa) |
| | Cabys_792 | Phosphopantothenoylcysteine decarboxylase. (181 aa) |
| | metG | metG methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa) |
| | rpsP | rpsP small subunit ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (124 aa) |
| | rplS | rplS LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (113 aa) |
| | rpsT | rpsT SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (85 aa) |
| | tuf-2 | Tuf translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa) |
| | rplK | rplK LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (140 aa) |
| | rplA | rplA LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (232 aa) |
| | rplJ | rplJ LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (173 aa) |
| | rplL | Large subunit ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (81 aa) |
| | rpsL | Small subunit ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (44 aa) |
| | rpsG | rpsG SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (155 aa) |
| | fusA | fusA translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase fa [...] (693 aa) |
| | tuf | Translation elongation factor 1A (EF-1A/EF-Tu). (396 aa) |
| | rpsJ | rpsJ SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | rplC | rplC LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (206 aa) |
| | rplD | rplD LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (209 aa) |
| | rplW | rplW LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa) |
| | rplB | rplB LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa) |
| | rpsS | rpsS SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (95 aa) |
| | rplV | rplV large subunit ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (114 aa) |
| | rpsC | rpsC SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (211 aa) |
| | rplP | rplP LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (135 aa) |
| | rpmC | rpmC LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (69 aa) |
| | s17P | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (67 aa) |
| | rplN | rplN LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (103 aa) |
| | rplX | rplX LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (111 aa) |
| | rplE | rplE LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (184 aa) |
| | rpsZ | rpsZ SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rpsH | rpsH SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rplF | rplF LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa) |
| | rplR | rplR LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (112 aa) |
| | rpsE | rpsE SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (168 aa) |
| | l30P | LSU ribosomal protein L30P. (71 aa) |
| | rplO | rplO LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa) |
| | infA | infA bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa) |
| | rpsM | rpsM SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (123 aa) |
| | rpsK | Small subunit ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (89 aa) |
| | rpsD | rpsD small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (204 aa) |
| | rplQ | rplQ large subunit ribosomal protein L17. (199 aa) |
