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queC queC gltX gltX cysS cysS ileS ileS APF18482.1 APF18482.1 glnS glnS APF18569.1 APF18569.1 coaD coaD guaA guaA APF18771.1 APF18771.1 nadE nadE thiI thiI leuS leuS uspA uspA APF19238.1 APF19238.1 APF19283.1 APF19283.1 APF19344.1 APF19344.1 nadD nadD Cabys_293 Cabys_293 Cabys_294 Cabys_294 tyrS tyrS APF20141.1 APF20141.1 APF20151.1 APF20151.1 sat sat nadE-2 nadE-2 mnmA mnmA panC panC argS argS valS valS gltX-2 gltX-2 metG metG Cabys_880 Cabys_880 Cabys_881 Cabys_881
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
queCqueC 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
gltXgltX glutamyl-tRNA synthetase/nondiscriminating glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (477 aa)
cysScysS cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (484 aa)
ileSileS Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1095 aa)
APF18482.1Argininosuccinate synthase. (402 aa)
glnSglnS glutaminyl-tRNA synthetase. (562 aa)
APF18569.1Glycerol-3-phosphate cytidylyltransferase. (154 aa)
coaDcoaD Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)
guaAguaA GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (522 aa)
APF18771.1Asparagine synthase (glutamine-hydrolysing). (658 aa)
nadEnadE NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (320 aa)
thiIthiI thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (387 aa)
leuSleuS leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (877 aa)
uspANucleotide-binding universal stress protein, UspA family. (300 aa)
APF19238.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (289 aa)
APF19283.1tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (325 aa)
APF19344.1D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (159 aa)
nadDnadD nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
Cabys_293Electron transfer flavoprotein beta subunit. (249 aa)
Cabys_294Electron transfer flavoprotein alpha subunit apoprotein. (317 aa)
tyrStyrS tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa)
APF20141.1Glutamine amidotransferase class-II:Asparagine synthase. (573 aa)
APF20151.1Asparagine synthase (glutamine-hydrolysing). (604 aa)
satSat sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (378 aa)
nadE-2nadE NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (275 aa)
mnmAmnmA tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa)
panCpanC pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
argSargS arginyl-tRNA synthetase. (544 aa)
valSvalS valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (896 aa)
gltX-2gltX glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa)
metGmetG methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa)
Cabys_880Electron transfer flavoprotein beta subunit. (296 aa)
Cabys_881Electron transfer flavoprotein alpha subunit apoprotein. (339 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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