STRINGSTRING
APF17812.1 APF17812.1 APF18155.1 APF18155.1 APF18316.1 APF18316.1 APF18457.1 APF18457.1 APF18522.1 APF18522.1 trpB trpB trpA trpA gcvPA gcvPA gcvPB gcvPB APF18870.1 APF18870.1 gcvH gcvH APF19132.1 APF19132.1 gcvT gcvT APF19615.1 APF19615.1 APF19667.1 APF19667.1 APF19677.1 APF19677.1 APF20003.1 APF20003.1 APF20013.1 APF20013.1 serC serC APF20063.1 APF20063.1 thrB thrB APF20065.1 APF20065.1 APF20544.1 APF20544.1 APF20656.1 APF20656.1 trpB-2 trpB-2 glyA glyA Cabys_78 Cabys_78 gpmI gpmI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APF17812.1Aspartate kinase; Belongs to the aspartokinase family. (456 aa)
APF18155.1Glycerate 2-kinase. (440 aa)
APF18316.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (242 aa)
APF18457.1Aspartate semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (354 aa)
APF18522.1L-threonine aldolase. (345 aa)
trpBtrpB tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa)
trpAtrpA tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
gcvPAgcvPA glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (429 aa)
gcvPBgcvPB glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
APF18870.1Threonine synthase. (425 aa)
gcvHgcvH glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
APF19132.1L-threonine aldolase. (347 aa)
gcvTgcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (358 aa)
APF19615.1Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
APF19667.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)
APF19677.1Cystathionine beta-synthase. (317 aa)
APF20003.1Homoserine dehydrogenase. (342 aa)
APF20013.1Homoserine dehydrogenase. (348 aa)
serCserC phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
APF20063.1Aspartate kinase; Belongs to the aspartokinase family. (467 aa)
thrBthrB homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (319 aa)
APF20065.1L-threonine synthase. (433 aa)
APF20544.1Dihydrolipoamide dehydrogenase. (475 aa)
APF20656.1Homoserine dehydrogenase. (436 aa)
trpB-2trpB tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (454 aa)
glyAglyA serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
Cabys_78Dihydrolipoamide dehydrogenase. (463 aa)
gpmIgpmI phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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