(19 nodes) ThiF/MoeB/HesA family network (Selaginella moellendorffii)

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Your Input:
	AXR1-1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (542 aa)
	D8RJ76_SELML	ThiF domain-containing protein. (457 aa)
	D8RCF4_SELML	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1007 aa)
	D8R6W3_SELML	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (708 aa)
	MOCS3	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (422 aa)
	D8TAC0_SELML	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (590 aa)
	D8QRN9_SELML	ThiF domain-containing protein. (399 aa)
	D8QP30_SELML	ThiF domain-containing protein. (407 aa)
	D8QNA7_SELML	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (698 aa)
	D8SG67_SELML	Rhodanese domain-containing protein. (407 aa)
	D8SC95_SELML	ThiF domain-containing protein. (329 aa)
	D8S2C6_SELML	E2_bind domain-containing protein. (449 aa)
	D8RVM4_SELML	E2_bind domain-containing protein. (449 aa)
	D8SHI4_SELML	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1021 aa)
	D8SIZ6_SELML	ThiF domain-containing protein. (380 aa)
	AXR1-2	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (542 aa)
	D8T3J7_SELML	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (590 aa)
	D8T4W4_SELML	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1007 aa)
	D8T5S9_SELML	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1059 aa)

Your Current Organism:

Selaginella moellendorffii

NCBI taxonomy Id: 88036
Other names: S. moellendorffii, Selaginella moellendorffii Hieron., Selaginella moellendorfii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXR1-1	D8QNA7_SELML	D8RVZ4	D8QNA7	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.424
AXR1-1	D8QRN9_SELML	D8RVZ4	D8QRN9	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	ThiF domain-containing protein.	0.412
AXR1-1	D8R6W3_SELML	D8RVZ4	D8R6W3	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.424
AXR1-1	D8RJ76_SELML	D8RVZ4	D8RJ76	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	ThiF domain-containing protein.	0.412
AXR1-1	D8RVM4_SELML	D8RVZ4	D8RVM4	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	E2_bind domain-containing protein.	0.992
AXR1-1	D8S2C6_SELML	D8RVZ4	D8S2C6	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	E2_bind domain-containing protein.	0.992
AXR1-1	D8T3J7_SELML	D8RVZ4	D8T3J7	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.453
AXR1-1	D8TAC0_SELML	D8RVZ4	D8TAC0	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.453
AXR1-2	D8QNA7_SELML	D8SVL4	D8QNA7	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.424
AXR1-2	D8QRN9_SELML	D8SVL4	D8QRN9	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	ThiF domain-containing protein.	0.412
AXR1-2	D8R6W3_SELML	D8SVL4	D8R6W3	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.424
AXR1-2	D8RJ76_SELML	D8SVL4	D8RJ76	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	ThiF domain-containing protein.	0.412
AXR1-2	D8RVM4_SELML	D8SVL4	D8RVM4	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	E2_bind domain-containing protein.	0.992
AXR1-2	D8S2C6_SELML	D8SVL4	D8S2C6	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	E2_bind domain-containing protein.	0.992
AXR1-2	D8T3J7_SELML	D8SVL4	D8T3J7	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.453
AXR1-2	D8TAC0_SELML	D8SVL4	D8TAC0	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family.	0.453
D8QNA7_SELML	AXR1-1	D8QNA7	D8RVZ4	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.424
D8QNA7_SELML	AXR1-2	D8QNA7	D8SVL4	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.424
D8QNA7_SELML	D8QRN9_SELML	D8QNA7	D8QRN9	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	ThiF domain-containing protein.	0.774
D8QNA7_SELML	D8R6W3_SELML	D8QNA7	D8R6W3	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.900