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hynB-2 hynB-2 DVU_0172 DVU_0172 DVU_0173 DVU_0173 DVU_0263 DVU_0263 DVU_0433 DVU_0433 DVU_0534 DVU_0534 DVU_0588 DVU_0588 qrcD qrcD qrcC qrcC qrcB qrcB DVU_0826 DVU_0826 DVU_0848 DVU_0848 DVU_1286 DVU_1286 DVU_1287 DVU_1287 DVU_1611 DVU_1611 DVU_1772 DVU_1772 DVU_1783 DVU_1783 hysB hysB hynB-1 hynB-1 DVU_2287 DVU_2287 hdrA hdrA DVU_2481 DVU_2481 DVU_2809 DVU_2809 DVU_2811 DVU_2811 DVU_3028 DVU_3028 DVU_3143 DVU_3143 DVU_3171 DVU_3171 DVU_3364 DVU_3364
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hynB-2Periplasmic [NiFe] hydrogenase, small subunit, isozyme 2; Identified by match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (304 aa)
DVU_0172Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037. (333 aa)
DVU_0173Thiosulfate reductase, putative; Identified by similarity to SP:P37600; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879. (733 aa)
DVU_0263Acidic cytochrome c3; Identified by similarity to SP:P94690. (126 aa)
DVU_0433Ech hydrogenase, subunit EchB, putative; Identified by similarity to GP:3005968; match to protein family HMM PF00146. (282 aa)
DVU_0534Hmc operon protein 3; HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates; Belongs to the NrfD family. (388 aa)
DVU_0588Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (236 aa)
qrcDMolybdopterin oxidoreductase, transmembrane subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The QrcD subunit anchors the protein complex to the membrane and likely interacts with the quinone pool. (419 aa)
qrcCMolybdopterin oxidoreductase, iron-sulfur cluster-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. QrcC is an electron- transferring subunit; its cubane iron sulfur clusters form a pathway for electron transfer between the he [...] (255 aa)
qrcBMolybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other [...] (691 aa)
DVU_0826Glycolate oxidase, iron-sulfur subunit, putative; Identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754. (440 aa)
DVU_0848Heterodisulfide reductase, putative; Identified by similarity to GP:1890204. (412 aa)
DVU_1286Reductase, transmembrane subunit, putative; Identified by match to protein family HMM PF03916. (387 aa)
DVU_1287Reductase, iron-sulfur binding subunit, putative; Identified by match to protein family HMM PF00037. (261 aa)
DVU_1611Molybdopterin oxidoreductase domain protein; Identified by match to protein family HMM PF00384; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (642 aa)
DVU_1772Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070. (673 aa)
DVU_1783Cysteine-rich domain protein; Identified by match to protein family HMM PF02754. (250 aa)
hysBPeriplasmic [NiFeSe] hydrogenase, small subunit; Identified by similarity to SP:P13063; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409. (317 aa)
hynB-1Periplasmic [NiFe] hydrogenase, small subunit, isozyme 1; Identified by similarity to SP:P21853; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (317 aa)
DVU_2287Hydrogenase, CooK subunit, selenocysteine-containing, putative; Selenoprotein; identified by similarity to GP:1515467; match to protein family HMM PF00146. (321 aa)
hdrAHeterodisulfide reductase, A subunit; Identified by similarity to GP:12642418; match to protein family HMM PF00037. (652 aa)
DVU_2481Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (260 aa)
DVU_2809Cytochrome c3; Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin (By similarity). Gamma chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The gamma subunit of formate dehydrogenase forms a c-type heme. (144 aa)
DVU_2811Formate dehydrogenase, beta subunit, putative; Beta chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The beta chain is an electron transfer unit. (219 aa)
DVU_3028Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754. (422 aa)
DVU_3143Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409. (529 aa)
DVU_3171Cytochrome c3; Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin. (129 aa)
DVU_3364Conserved hypothetical protein; Identified by similarity to OMNI:NTL01TT1406. (307 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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