Your Input: | |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily. (419 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. (381 aa) |
| | aroA-2 | Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids; Belongs to the DeoC/FbaB aldolase family. ADHS subfamily. (266 aa) |
| | DVU_0461 | Predicted 3-dehydroquinate synthase; Identified by similarity to OMNI:NTL01AA01322. (323 aa) |
| | DVU_0462 | Chorismate mutase/prephenate dehydratase; Identified by similarity to SP:P07022; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807. (391 aa) |
| | DVU_0465 | Anthranilate synthase, component I; Identified by similarity to SP:O66849; match to protein family HMM PF00425; match to protein family HMM PF04715. (532 aa) |
| | trpG | Anthranilate synthase, glutamine amidotransferase component; Identified by similarity to SP:Q08654; match to protein family HMM PF00117; match to protein family HMM TIGR00566. (209 aa) |
| | trpB-1 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa) |
| | DVU_0112 | Deoxyribodipyrimidine photolyase, putative; Identified by similarity to SP:P05327; match to protein family HMM PF00875; match to protein family HMM PF03441. (474 aa) |
| | DVU_0173 | Thiosulfate reductase, putative; Identified by similarity to SP:P37600; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879. (733 aa) |
| | DVU_0278 | Glyoxalase family protein; Identified by similarity to OMNI:NTL01FN1550; match to protein family HMM PF00903. (140 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; Belongs to the HisA/HisF family. (259 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) |
| | DVU_0298 | Hypothetical protein; Identified by Glimmer2; putative. (261 aa) |
| | DVU_0319 | Identified by similarity to GP:20560072; match to protein family HMM PF01370. (341 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (437 aa) |
| | DVU_0342 | Identified by match to protein family HMM PF01370. (304 aa) |
| | DVU_0343 | Identified by similarity to SP:P23522; match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family. (260 aa) |
| | pabB | Para-aminobenzoate synthase, component I; Identified by match to protein family HMM PF00425. (334 aa) |
| | pabA | Para-aminobenzoate/anthranilate synthase glutamine amidotransferase; Identified by similarity to SP:P28819; match to protein family HMM PF00117. (184 aa) |
| | rlpA | Rare lipoprotein A, putative; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (243 aa) |
| | rlpA-2 | Rare lipoprotein A family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (214 aa) |
| | speA | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (659 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218. (257 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpB family. (395 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. (257 aa) |
| | DVU_0499 | Conserved hypothetical protein TIGR00149; Identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149. (131 aa) |
| | DVU_0554 | Identified by match to protein family HMM PF01370. (312 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (341 aa) |
| | cbiKp | Chelatase, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. (297 aa) |
| | DVU_0734 | Uroporphyrinogen III synthase/methyltransferase; Identified by similarity to GP:12655814; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01369; match to protein family HMM TIGR01469. (503 aa) |
| | DVU_0854 | NirD protein, putative; Identified by similarity to SP:Q52522. (176 aa) |
| | hemB | Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (330 aa) |
| | DVU_0867 | Aromatic amino acid decarboxylase, putative; Identified by similarity to GP:6900962; match to protein family HMM PF00282. (497 aa) |
| | DVU_0887 | Transglycosylase, putative; Identified by similarity to OMNI:PP4971; match to protein family HMM PF03562. (424 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa) |
| | pyrF | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (235 aa) |
| | nth | Endonuclease III, putative; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (285 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. (198 aa) |
| | DVU_1059 | Aminotransferase, putative. (390 aa) |
| | DVU_1064 | Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342. (642 aa) |
| | argH | Argininosuccinate lyase; Identified by similarity to SP:O34858; match to protein family HMM PF00206; match to protein family HMM TIGR00838; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. (460 aa) |
| | DVU_1128 | Lysozyme, putative; Identified by match to protein family HMM PF01464. (221 aa) |
| | psd | Phosphatidylserine decarboxylase-related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (217 aa) |
| | DVU_0440 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01TT0248; Belongs to the UPF0597 family. (443 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (167 aa) |
| | DVU_3043 | Hypothetical protein; Identified by Glimmer2; putative. (343 aa) |
| | DVU_3047 | Aminotransferase, class IV; Identified by match to protein family HMM PF01063. (315 aa) |
| | mltG | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (440 aa) |
| | DVU_3167 | Heme biosynthesis protein, putative; Identified by similarity to SP:Q52522. (160 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa) |
| | DVU_3205 | Transglycosylase SLT domain protein; Identified by match to protein family HMM PF01464. (481 aa) |
| | thrC | Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (470 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (365 aa) |
| | DVU_3264 | Tartrate dehydratase alpha subunit, putative; Identified by similarity to SP:P05847; match to protein family HMM PF05681; match to protein family HMM TIGR00722. (279 aa) |
| | DVU_3265 | Tartrate dehydratase beta subunit, putative; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. (183 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa) |
| | DVU_3356 | Identified by similarity to GP:5739472; match to protein family HMM PF01370. (335 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by similarity to SP:P51785; match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (554 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa) |
| | DVU_2418 | Identified by match to protein family HMM PF04892. (140 aa) |
| | DVU_2455 | Identified by match to protein family HMM PF01370. (316 aa) |
| | DVU_2540 | 2-hydroxyglutaryl-CoA dehydratase, D-component; Identified by similarity to GP:38802; match to protein family HMM PF06050. (380 aa) |
| | DVU_2560 | Conserved domain protein; Identified by similarity to SP:O84537. (128 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | DVU_2657 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to protein family HMM PF01242. (120 aa) |
| | queE | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (216 aa) |
| | DVU_2699 | Transglycosylase SLT domain protein; Identified by match to protein family HMM PF01464. (215 aa) |
| | mqnD | Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (280 aa) |
| | mqnA | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (280 aa) |
| | DVU_2772 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01TE2295. (440 aa) |
| | DVU_2824 | Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. (828 aa) |
| | ribAB | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (409 aa) |
| | DVU_1264 | Transglycosylase SLT domain protein; Identified by match to protein family HMM PF01464. (253 aa) |
| | dacA | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (248 aa) |
| | DVU_1352 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to protein family HMM PF01242. (129 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; Identified by match to protein family HMM PF01370; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (340 aa) |
| | cbiKc | Heme-binding protein, putative; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. (282 aa) |
| | DVU_1404 | Radical SAM domain protein; Identified by match to protein family HMM PF04055. (368 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Identified by match to protein family HMM PF01964; match to protein family HMM TIGR00190. (429 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (395 aa) |
| | DVU_1463 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. (225 aa) |
| | DVU_1508 | Conserved hypothetical protein; Identified by similarity to GP:27550078. (135 aa) |
| | DVU_1600 | Adenylate cyclase; Identified by match to protein family HMM PF01928. (203 aa) |
| | DVU_1611 | Molybdopterin oxidoreductase domain protein; Identified by match to protein family HMM PF00384; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (642 aa) |
| | lysA-1 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (412 aa) |
| | DVU_1658 | Transaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (155 aa) |
| | DVU_1728 | Conserved hypothetical protein; Identified by similarity to GP:16506030. (138 aa) |
| | DVU_1766 | Aspartate ammonia-lyase, putative; Identified by similarity to SP:P26899; match to protein family HMM PF00206. (470 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (214 aa) |
| | cynT | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (245 aa) |
| | DVU_1834 | Pyruvate carboxylase, putative; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1225 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | aspA | Aspartate ammonia-lyase; Identified by similarity to SP:P07346; match to protein family HMM PF00206; match to protein family HMM TIGR00839. (468 aa) |
| | purB | Adenylosuccinate lyase; Identified by similarity to SP:P12047; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (430 aa) |
| | ltaE | Threonine aldolase, low-specificity; Identified by similarity to SP:O50584. (340 aa) |
| | nnrD | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (574 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II; Identified by similarity to SP:P13243; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (307 aa) |
| | DVU_2147 | L-serine dehydratase, putative; Identified by match to protein family HMM PF03313; match to protein family HMM PF03315. (502 aa) |
| | DVU_2202 | Transglycosylase SLT domain/bacterial extracellular solute-binding domain protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial [...] (505 aa) |
| | tnaA | Tryptophanase; Identified by similarity to SP:Q59342; match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. (462 aa) |
| | cobD | Cobalamin biosynthesis protein CobD, putative; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (320 aa) |
| | DVU_2272 | Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. (817 aa) |
| | DVU_2320 | Identified by match to protein family HMM PF01977. (612 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa) |
| | nspC | Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (390 aa) |
