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fdnG-3 fdnG-3 DVU_0535 DVU_0535 fdnG-1 fdnG-1 qrcB qrcB DVU_1287 DVU_1287 hydB hydB hysB hysB hynB-1 hynB-1 fdnG-2 fdnG-2 hynB-2 hynB-2 DVU_2661 DVU_2661 DVU_2798 DVU_2798 DVU_2804 DVU_2804 DVU_3143 DVU_3143
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fdnG-3Formate dehydrogenase, alpha subunit, selenocysteine-containing; Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site. (1012 aa)
DVU_0535Hmc operon protein 2; HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates. ORF2 is a transmembrane redox protein. (370 aa)
fdnG-1Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553. (1005 aa)
qrcBMolybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other [...] (691 aa)
DVU_1287Reductase, iron-sulfur binding subunit, putative; Identified by match to protein family HMM PF00037. (261 aa)
hydBPeriplasmic [Fe] hydrogenase, small subunit; May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. (123 aa)
hysBPeriplasmic [NiFeSe] hydrogenase, small subunit; Identified by similarity to SP:P13063; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409. (317 aa)
hynB-1Periplasmic [NiFe] hydrogenase, small subunit, isozyme 1; Identified by similarity to SP:P21853; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (317 aa)
fdnG-2Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa)
hynB-2Periplasmic [NiFe] hydrogenase, small subunit, isozyme 2; Identified by match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (304 aa)
DVU_2661Twin-arginine translocation pathway signal sequence domain protein. (521 aa)
DVU_2798ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (336 aa)
DVU_2804Identified by match to protein family HMM TIGR01409. (385 aa)
DVU_3143Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409. (529 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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