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qrcB qrcB ngr ngr DVU_0531 DVU_0531 DVU_0535 DVU_0535 hmcA hmcA DVU_0624 DVU_0624 qrcD qrcD qrcC qrcC hydA hydA DVU_1812 DVU_1812 DVU_1815 DVU_1815 cyf cyf DVU_1951 DVU_1951 DVU_2014 DVU_2014 DVU_2680 DVU_2680 rnfD rnfD rnfG rnfG rnfE rnfE rnfA rnfA rnfB rnfB DVU_2809 DVU_2809 DVU_2811 DVU_2811 fdnG-3 fdnG-3 poR poR rdl rdl rr rr DVU_3171 DVU_3171 rbO rbO rub rub roO roO cydA cydA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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Your Input:
qrcBMolybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other [...] (691 aa)
ngrNigerythrin; Exhibits NADH peroxidase activity (in vitro). (202 aa)
DVU_0531Hmc operon protein 6; HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates. ORF6 is a redox protein. (461 aa)
DVU_0535Hmc operon protein 2; HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates. ORF2 is a transmembrane redox protein. (370 aa)
hmcAHigh-molecular-weight cytochrome C; HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates. (560 aa)
DVU_0624NapC/NirT cytochrome c family protein; Electron donor subunit of the cytochrome c nitrite reductase holocomplex NrfHA. Acquires electrons from the menaquinone pool and mediates their transfer to the catalytic subunit NrfA in an anaerobic respiratory process of nitrite. The other biological function of the NrfHA holocomplex is to detoxify nitrite. This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced by other organisms living in the same environment (Probable). Belongs to the NapC/NirT/NrfH family. (159 aa)
qrcDMolybdopterin oxidoreductase, transmembrane subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The QrcD subunit anchors the protein complex to the membrane and likely interacts with the quinone pool. (419 aa)
qrcCMolybdopterin oxidoreductase, iron-sulfur cluster-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. QrcC is an electron- transferring subunit; its cubane iron sulfur clusters form a pathway for electron transfer between the he [...] (255 aa)
hydAPeriplasmic [Fe] hydrogenase, large subunit; May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. (421 aa)
DVU_1812Cytochrome c oxidase, subunit II, putative; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (426 aa)
DVU_1815Cytochrome c oxidase, subunit I, putative; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (541 aa)
cyfCytochrome c-553; Natural electron acceptor for a formate dehydrogenase. (103 aa)
DVU_1951Indolepyruvate ferredoxin oxidoreductase, alpha subunit, putative; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (616 aa)
DVU_2014Identified by match to protein family HMM PF00753; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (391 aa)
DVU_2680Flavodoxin; Low-potential electron donor to a number of redox enzymes; Belongs to the flavodoxin family. (148 aa)
rnfDElectron transport complex protein RnfD, putative; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (318 aa)
rnfGElectron transport complex protein RnfG, putative; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (191 aa)
rnfEElectron transport complex protein RnfE, putative; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (223 aa)
rnfAElectron transport complex protein RnfA, putative; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (191 aa)
rnfBIron-sulfur cluster-binding protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (295 aa)
DVU_2809Cytochrome c3; Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin (By similarity). Gamma chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The gamma subunit of formate dehydrogenase forms a c-type heme. (144 aa)
DVU_2811Formate dehydrogenase, beta subunit, putative; Beta chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The beta chain is an electron transfer unit. (219 aa)
fdnG-3Formate dehydrogenase, alpha subunit, selenocysteine-containing; Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site. (1012 aa)
poRPyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. (1215 aa)
rdlIdentified by match to protein family HMM PF00301; Belongs to the rubredoxin family. (75 aa)
rrRubrerythrin; May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide. (191 aa)
DVU_3171Cytochrome c3; Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin. (129 aa)
rbODesulfoferrodoxin; Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity; Belongs to the desulfoferrodoxin family. (126 aa)
rubRubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (52 aa)
roORubredoxin-oxygen oxidoreductase; Identified by similarity to SP:Q9F0J6; match to protein family HMM PF00258; match to protein family HMM PF00753. (402 aa)
cydACytochrome d ubiquinol oxidase, subunit I; Identified by similarity to SP:P94364; match to protein family HMM PF01654. (433 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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