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| | poR | Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. (1215 aa) |
| | DVU_1412 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (386 aa) |
| | tpX | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (172 aa) |
| | fabG | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (377 aa) |
| | aor | Aldehyde:ferredoxin oxidoreductase, tungsten-containing; Identified by similarity to SP:Q51739; match to protein family HMM PF01314; match to protein family HMM PF02730. (576 aa) |
| | guaB | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (485 aa) |
| | DVU_1037 | Mercuric reductase, putative; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF02852. (480 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. (291 aa) |
| | queF | GTP cyclohydrolase I family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (165 aa) |
| | hom | Homoserine dehydrogenase; Identified by similarity to SP:P19582; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (424 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (408 aa) |
| | aprA | Adenylyl-sulphate reductase, alpha subunit; Identified by similarity to GP:7109235; match to protein family HMM TIGR02061. (664 aa) |
| | aprB | Adenylylsulphate reductase, beta subunit; Identified by similarity to GP:7109234; match to protein family HMM PF00037; match to protein family HMM TIGR02060. (167 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa) |
| | fabI | Enoyl-(acyl-carrier-protein) reductase; Identified by similarity to SP:P29132; match to protein family HMM PF00106. (254 aa) |
| | qrcB | Molybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other [...] (691 aa) |
| | qrcC | Molybdopterin oxidoreductase, iron-sulfur cluster-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. QrcC is an electron- transferring subunit; its cubane iron sulfur clusters form a pathway for electron transfer between the he [...] (255 aa) |
| | DVU_0661 | Dihydrouridine synthase family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (332 aa) |
| | nrfA | Cytochrome c nitrite reductase, catalytic subunit NfrA, putative; Catalytic subunit of the cytochrome c nitrite reductase holocomplex NrfHA. Has both nitrite and sulfite reductase activities. Catalyzes the reduction of nitrite to ammonia, consuming six electrons acquired by the electron donor subunit NrfH from the menaquinone pool, in an anaerobic respiratory process of nitrite. The other biological function of the NrfHA holocomplex is to detoxify nitrite. This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced [...] (524 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa) |
| | fdnG-1 | Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553. (1005 aa) |
| | msrB | Peptide methionine sulfoxide reductase MsrB; Identified by similarity to SP:P14930; match to protein family HMM PF01641; match to protein family HMM TIGR00357. (143 aa) |
| | ald | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. (370 aa) |
| | gap-1 | Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (354 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183. (380 aa) |
| | DVU_0464 | Prephenate dehydrogenase; Identified by match to protein family HMM PF02153. (255 aa) |
| | lys1 | Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. (396 aa) |
| | dvsB | Dissimilatory sulfite reductase beta subunit; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria. (381 aa) |
| | trxB-1 | Thioredoxin reductase; Identified by similarity to SP:P50971; match to protein family HMM PF00070. (305 aa) |
| | DVU_0339 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (301 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | DVU_0173 | Thiosulfate reductase, putative; Identified by similarity to SP:P37600; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879. (733 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (301 aa) |
| | wcaG | GDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (323 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (290 aa) |
| | lpdA | 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. (456 aa) |
| | gcvPB | Glycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. (481 aa) |
| | gcvPA | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. (443 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa) |
| | DVU_1463 | Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470. (225 aa) |
| | mop | Aldehyde oxidoreductase; Identified by similarity to SP:Q46509; match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738. (906 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855. (578 aa) |
| | porB | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to GP:1565184. (284 aa) |
| | DVU_3379 | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (777 aa) |
| | putA | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1006 aa) |
| | pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (307 aa) |
| | cydA | Cytochrome d ubiquinol oxidase, subunit I; Identified by similarity to SP:P94364; match to protein family HMM PF01654. (433 aa) |
| | cydB | Cytochrome d ubiquinol oxidase, subunit II; Identified by similarity to SP:P94365; match to protein family HMM PF02322; match to protein family HMM TIGR00203. (341 aa) |
| | frdB | Fumarate reductase, iron-sulfur protein; Identified by similarity to SP:P17596; match to protein family HMM PF00037; match to protein family HMM TIGR00384. (247 aa) |
| | fdrA | Fumarate reductase, flavoprotein subunit; Identified by similarity to GP:13160058; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812. (612 aa) |
| | roO | Rubredoxin-oxygen oxidoreductase; Identified by similarity to SP:Q9F0J6; match to protein family HMM PF00258; match to protein family HMM PF00753. (402 aa) |
| | rbO | Desulfoferrodoxin; Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity; Belongs to the desulfoferrodoxin family. (126 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Identified by similarity to SP:P37606; match to protein family HMM PF01210; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (330 aa) |
| | DVU_3132 | Glycerol-3-phosphate dehydrogenase, FAD-dependent; Identified by similarity to SP:P18158; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (546 aa) |
| | queH | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (217 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa) |
| | DVU_1597 | Sulfite reductase, assimilatory-type; This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. (218 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (259 aa) |
| | DVU_1611 | Molybdopterin oxidoreductase domain protein; Identified by match to protein family HMM PF00384; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (642 aa) |
| | arsC | Arsenate reductase; Identified by similarity to SP:P45947; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (147 aa) |
| | hydA | Periplasmic [Fe] hydrogenase, large subunit; May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. (421 aa) |
| | hydB | Periplasmic [Fe] hydrogenase, small subunit; May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. (123 aa) |
| | hydC | [Fe] hydrogenase gamma; Identified by similarity to GP:40828; match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906. (606 aa) |
| | nadB | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (528 aa) |
| | DVU_1812 | Cytochrome c oxidase, subunit II, putative; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (426 aa) |
| | DVU_1814 | Cytochrome c oxidase, subunit III, putative; Identified by similarity to SP:P50677; match to protein family HMM PF00510. (203 aa) |
| | DVU_1815 | Cytochrome c oxidase, subunit I, putative; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (541 aa) |
| | trxB-2 | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM TIGR01292. (307 aa) |
| | ugd | UDP-glucose 6-dehydrogenase; Identified by similarity to SP:O54068; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (445 aa) |
| | hysB | Periplasmic [NiFeSe] hydrogenase, small subunit; Identified by similarity to SP:P13063; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409. (317 aa) |
| | hysA | Periplasmic [NiFeSe] hydrogenase, large subunit, selenocysteine-containing; Selenoprotein; identified by match to protein family HMM PF00374. (510 aa) |
| | hynB-1 | Periplasmic [NiFe] hydrogenase, small subunit, isozyme 1; Identified by similarity to SP:P21853; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (317 aa) |
| | hynA-1 | Periplasmic [NiFe] hydrogenase, large subunit, isozyme 1; Identified by similarity to SP:P21852; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (566 aa) |
| | DVU_1951 | Indolepyruvate ferredoxin oxidoreductase, alpha subunit, putative; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (616 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa) |
| | msrA | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (208 aa) |
| | hcp | Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O; Belongs to the HCP family. (553 aa) |
| | DVU_2014 | Identified by match to protein family HMM PF00753; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (391 aa) |
| | DVU_2064 | Oxidoreductase, 2-nitropropane dioxygenase family; Identified by match to protein family HMM PF03060. (373 aa) |
| | cooS | Carbon monoxide dehydrogenase; Identified by similarity to SP:P31896. (629 aa) |
| | gap-2 | Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534. (333 aa) |
| | pdxA | Pyridoxal phosphate biosynthetic protein PdxA; Identified by similarity to SP:P19624; match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. (406 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (265 aa) |
| | sodB | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (196 aa) |
| | gltA | Glutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM TIGR01316. (476 aa) |
| | fdnG-2 | Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (296 aa) |
| | hynB-2 | Periplasmic [NiFe] hydrogenase, small subunit, isozyme 2; Identified by match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. (304 aa) |
| | hynA-2 | Periplasmic [NiFe] hydrogenase, large subunit, isozyme 2; Identified by similarity to SP:P21852; match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (549 aa) |
| | hcp-2 | Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (539 aa) |
| | acpD | Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (209 aa) |
| | DVU_2674 | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa) |
| | qor | Quinone oxidoreductase; Identified by similarity to SP:P28304; match to protein family HMM PF00107. (325 aa) |
| | mqnC | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (375 aa) |
| | dsvC | Dissimilatory sulfite reductase, gamma subunit; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria; Belongs to the DsrC/TusE family. (105 aa) |
| | fdnG-3 | Formate dehydrogenase, alpha subunit, selenocysteine-containing; Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site. (1012 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (357 aa) |
