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DVU_0848 DVU_0848 dsvA dsvA dvsB dvsB DVU_0449 DVU_0449 hmcA hmcA cyf cyf DVU_2285 DVU_2285 hdrA hdrA hdrB hdrB DVU_2682 DVU_2682 DVU_2683 DVU_2683 DVU_3026 DVU_3026 DVU_3276 DVU_3276 DVU_3284 DVU_3284 qrcC qrcC qrcB qrcB flr flr DVU_0263 DVU_0263 qrcD qrcD DVU_0305 DVU_0305 ldh ldh
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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DVU_0848Heterodisulfide reductase, putative; Identified by similarity to GP:1890204. (412 aa)
dsvADissimilatory sulfite reductase alpha subunit; Part of the complex that catalyzes the reduction of sulfite to sulfide. The alpha and beta subunits may have arisen by gene duplication. They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme. (437 aa)
dvsBDissimilatory sulfite reductase beta subunit; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria. (381 aa)
DVU_0449Sensor/response regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (1513 aa)
hmcAHigh-molecular-weight cytochrome C; HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates. (560 aa)
cyfCytochrome c-553; Natural electron acceptor for a formate dehydrogenase. (103 aa)
DVU_2285L-lactate permease family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (506 aa)
hdrAHeterodisulfide reductase, A subunit; Identified by similarity to GP:12642418; match to protein family HMM PF00037. (652 aa)
hdrBHeterodisulfide reductase, B subunit; Identified by similarity to GP:3378542; match to protein family HMM PF02754. (334 aa)
DVU_2682DedA family protein; Identified by similarity to GP:13446681; match to protein family HMM PF00597. (213 aa)
DVU_2683L-lactate permease family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (516 aa)
DVU_3026L-lactate permease family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (570 aa)
DVU_3276Identified by similarity to SP:P08813; match to protein family HMM PF00037. (62 aa)
DVU_3284L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (543 aa)
qrcCMolybdopterin oxidoreductase, iron-sulfur cluster-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. QrcC is an electron- transferring subunit; its cubane iron sulfur clusters form a pathway for electron transfer between the he [...] (255 aa)
qrcBMolybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other [...] (691 aa)
flrFlavoredoxin; Identified by similarity to SP:Q9KIT1; match to protein family HMM PF01613. (190 aa)
DVU_0263Acidic cytochrome c3; Identified by similarity to SP:P94690. (126 aa)
qrcDMolybdopterin oxidoreductase, transmembrane subunit, putative; Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The QrcD subunit anchors the protein complex to the membrane and likely interacts with the quinone pool. (419 aa)
DVU_0305Ferredoxin II; Identified by similarity to SP:P10624; match to protein family HMM PF00037. (64 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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