STRINGSTRING
DVU_0152 DVU_0152 DVU_0246 DVU_0246 eno eno aroA-2 aroA-2 gap-1 gap-1 ldh ldh DVU_0685 DVU_0685 acs acs DVU_0889 DVU_0889 DVU_1035 DVU_1035 lpdA lpdA pgm pgm glpX glpX porA porA porB porB gpmA gpmA tpiA tpiA DVU_1833 DVU_1833 fbp fbp DVU_1945 DVU_1945 DVU_1946 DVU_1946 pfkA pfkA fba fba gap-2 gap-2 DVU_2250 DVU_2250 DVU_2396 DVU_2396 DVU_2405 DVU_2405 pyk pyk pgk pgk DVU_2739 DVU_2739 DVU_2885 DVU_2885 DVU_2905 DVU_2905 gpm gpm acsA acsA poR poR DVU_3214 DVU_3214 pgi pgi DVU_3237 DVU_3237 DVU_3348 DVU_3348 DVU_3349 DVU_3349
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVU_0152Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P42850; match to protein family HMM PF00391; match to protein family HMM PF01326. (853 aa)
DVU_0246Pyruvate phosphate dikinase, PEP/pyruvate binding domain protein; Identified by similarity to SP:O29548; match to protein family HMM PF00391; match to protein family HMM PF01326. (744 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (437 aa)
aroA-2Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids; Belongs to the DeoC/FbaB aldolase family. ADHS subfamily. (266 aa)
gap-1Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (309 aa)
DVU_0685Phosphomannomutase; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (453 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (648 aa)
DVU_0889Phosphonopyruvate decarboxylase-related protein; Identified by match to protein family HMM PF01676. (379 aa)
DVU_1035Glucokinase, putative; Belongs to the bacterial glucokinase family. (339 aa)
lpdA2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. (456 aa)
pgmPhosphoglucomutase, alpha-D-glucose phosphate-specific; Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; match to protein family HMM TIGR01132. (551 aa)
glpXFructose-1,6-bisphosphatase, class II; Identified by similarity to SP:P28860; match to protein family HMM PF03320; match to protein family HMM TIGR00330; Belongs to the FBPase class 2 family. (327 aa)
porAPyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855. (578 aa)
porBPyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to GP:1565184. (284 aa)
gpmAPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
DVU_1833Phosphoenolpyruvate synthase, putative; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896. (1191 aa)
fbpFructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. (337 aa)
DVU_1945Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855. (382 aa)
DVU_1946Pyruvate ferredoxin oxidoreductase, beta subunit, putative; Identified by match to protein family HMM PF02775. (276 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (444 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; Identified by similarity to SP:P13243; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (307 aa)
gap-2Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534. (333 aa)
DVU_2250Identified by match to protein family HMM PF00501. (551 aa)
DVU_2396Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P31005; match to protein family HMM PF00465. (380 aa)
DVU_2405Alcohol dehydrogenase, iron-containing; Identified by similarity to GP:2393887; match to protein family HMM PF00465. (393 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (469 aa)
pgkPhosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (393 aa)
DVU_2739Pyruvate phosphate dikinase, PEP/pyruvate binding domain protein; Identified by similarity to SP:O29548; match to protein family HMM PF00391; match to protein family HMM PF01326. (945 aa)
DVU_2885Alcohol dehydrogenase, iron-containing; Identified by similarity to GP:155577; match to protein family HMM PF00465. (397 aa)
DVU_2905Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:Q04944; match to protein family HMM PF00465. (392 aa)
gpmPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
acsAacetoacetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (661 aa)
poRPyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. (1215 aa)
DVU_3214Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P42850; match to protein family HMM PF00391; match to protein family HMM PF01326. (884 aa)
pgiGlucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342. (447 aa)
DVU_3237Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P23538; match to protein family HMM PF00391. (773 aa)
DVU_3348Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit, putative. (245 aa)
DVU_3349Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; Identified by match to protein family HMM PF01855. (357 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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