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DVU_0130 DVU_0130 fdnG-1 fdnG-1 DVU_0588 DVU_0588 glcB glcB acs acs DVU_0765 DVU_0765 DVU_0827 DVU_0827 DVU_1064 DVU_1064 amiE amiE glyA glyA glnN glnN DVU_1358 DVU_1358 DVU_1412 DVU_1412 lpdA lpdA gcvPB gcvPB gcvPA gcvPA gcvH gcvH purU purU gcvT gcvT DVU_2250 DVU_2250 DVU_2481 DVU_2481 fdnG-2 fdnG-2 DVU_2811 DVU_2811 fdnG-3 fdnG-3 acsA acsA glcD glcD DVU_3028 DVU_3028 DVU_3121 DVU_3121 glnA glnA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
DVU_0130Phosphoglycolate phosphatase, putative; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. (220 aa)
fdnG-1Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553. (1005 aa)
DVU_0588Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (236 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (729 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (648 aa)
DVU_0765Hydroxypyruvate reductase, putative; Identified by similarity to SP:Q44472; match to protein family HMM PF05161. (454 aa)
DVU_0827Glycolate oxidase, subunit GlcD, putative; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913. (471 aa)
DVU_1064Aconitate hydratase, putative; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR01342. (642 aa)
amiEAliphatic amidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. (334 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. (412 aa)
glnNGlutamine synthetase, type III; Identified by similarity to GP:9651982; match to protein family HMM PF00120; Belongs to the glutamine synthetase family. (726 aa)
DVU_1358Hydrolase, haloacid dehalogenase-like family; Identified by match to protein family HMM PF00702. (215 aa)
DVU_1412D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
lpdA2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to SP:O34324; match to protein family HMM PF00070; match to protein family HMM PF02852. (456 aa)
gcvPBGlycine cleavage system P protein, subunit 2; Identified by similarity to SP:P54377; Belongs to the GcvP family. (481 aa)
gcvPAGlycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily. (443 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa)
gcvTGlycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528. (362 aa)
DVU_2250Identified by match to protein family HMM PF00501. (551 aa)
DVU_2481Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (260 aa)
fdnG-2Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa)
DVU_2811Formate dehydrogenase, beta subunit, putative; Beta chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The beta chain is an electron transfer unit. (219 aa)
fdnG-3Formate dehydrogenase, alpha subunit, selenocysteine-containing; Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site. (1012 aa)
acsAacetoacetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (661 aa)
glcDGlycolate oxidase, subunit GlcD; Identified by similarity to SP:P52075; match to protein family HMM PF01565; match to protein family HMM PF02913. (461 aa)
DVU_3028Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02754. (422 aa)
DVU_3121Aminotransferase, class V; Identified by match to protein family HMM PF00266. (376 aa)
glnAGlutamine synthetase, type I; Identified by similarity to SP:P12425; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. (447 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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