(21 nodes) Butanoate metabolism network (Desulfovibrio vulgaris Hildenborough)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ilvB-1	Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. (563 aa)
	DVU_0361	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842. (107 aa)
	ilvN-1	Acetolactate synthase, small subunit; Identified by similarity to SP:P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119. (159 aa)
	ptB	Phosphotransbutyrylase; Identified by similarity to GP:457633; match to protein family HMM PF01515. (343 aa)
	buk	Butyrate kinase; Identified by similarity to SP:Q05619; match to protein family HMM PF00871; Belongs to the acetokinase family. (372 aa)
	ilvB-2	Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P00893; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. (563 aa)
	ilvN-2	Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119. (162 aa)
	porA	Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855. (578 aa)
	porB	Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to GP:1565184. (284 aa)
	DVU_1945	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855. (382 aa)
	DVU_1946	Pyruvate ferredoxin oxidoreductase, beta subunit, putative; Identified by match to protein family HMM PF02775. (276 aa)
	DVU_2272	Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901. (817 aa)
	DVU_2674	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (239 aa)
	DVU_2824	Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901. (828 aa)
	poR	Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855. (1215 aa)
	frdC	Fumarate reductase, cytochrome b subunit; Identified by similarity to SP:P17413. (216 aa)
	fdrA	Fumarate reductase, flavoprotein subunit; Identified by similarity to GP:13160058; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01812. (612 aa)
	frdB	Fumarate reductase, iron-sulfur protein; Identified by similarity to SP:P17596; match to protein family HMM PF00037; match to protein family HMM TIGR00384. (247 aa)
	DVU_3293	Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (547 aa)
	DVU_3348	Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit, putative. (245 aa)
	DVU_3349	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; Identified by match to protein family HMM PF01855. (357 aa)

Your Current Organism:

Desulfovibrio vulgaris Hildenborough

NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVU_0361	DVU_1945	DVU_0361	DVU_1945	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	0.673
DVU_0361	DVU_1946	DVU_0361	DVU_1946	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate ferredoxin oxidoreductase, beta subunit, putative; Identified by match to protein family HMM PF02775.	0.665
DVU_0361	DVU_2272	DVU_0361	DVU_2272	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901.	0.904
DVU_0361	DVU_2824	DVU_0361	DVU_2824	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901.	0.903
DVU_0361	DVU_3293	DVU_0361	DVU_3293	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.	0.990
DVU_0361	DVU_3348	DVU_0361	DVU_3348	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit, putative.	0.657
DVU_0361	DVU_3349	DVU_0361	DVU_3349	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; Identified by match to protein family HMM PF01855.	0.668
DVU_0361	ilvB-1	DVU_0361	DVU_0360	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.	0.998
DVU_0361	ilvB-2	DVU_0361	DVU_1376	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P00893; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.	0.989
DVU_0361	ilvN-1	DVU_0361	DVU_0626	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Acetolactate synthase, small subunit; Identified by similarity to SP:P37252; match to protein family HMM PF01842; match to protein family HMM TIGR00119.	0.938
DVU_0361	ilvN-2	DVU_0361	DVU_1377	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Acetolactate synthase, small subunit; Identified by similarity to SP:P00894; match to protein family HMM PF01842; match to protein family HMM TIGR00119.	0.914
DVU_0361	poR	DVU_0361	DVU_3025	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate-ferredoxin oxidoreductase; Identified by similarity to GP:1770208; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855.	0.923
DVU_0361	porA	DVU_0361	DVU_1569	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to GP:43498; match to protein family HMM PF01558; match to protein family HMM PF01855.	0.697
DVU_0361	porB	DVU_0361	DVU_1570	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to GP:1565184.	0.657
DVU_1945	DVU_0361	DVU_1945	DVU_0361	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Acetolactate synthase III, small subunit, putative; Identified by match to protein family HMM PF01842.	0.673
DVU_1945	DVU_1946	DVU_1945	DVU_1946	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Pyruvate ferredoxin oxidoreductase, beta subunit, putative; Identified by match to protein family HMM PF02775.	0.999
DVU_1945	DVU_2272	DVU_1945	DVU_2272	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Formate acetyltransferase, putative; Identified by similarity to SP:P32674; match to protein family HMM PF01228; match to protein family HMM PF02901.	0.906
DVU_1945	DVU_2674	DVU_1945	DVU_2674	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.474
DVU_1945	DVU_2824	DVU_1945	DVU_2824	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Formate acetyltransferase; Identified by match to protein family HMM PF01228; match to protein family HMM PF02901.	0.905
DVU_1945	DVU_3293	DVU_1945	DVU_3293	Pyruvate ferredoxin oxidoreductase, alpha subunit, putative; Identified by match to protein family HMM PF01855.	Thiamine pyrophosphate-requiring enzyme; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.	0.684

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