STRINGSTRING
DVU_0152 DVU_0152 DVU_0246 DVU_0246 eno eno DVU_0339 DVU_0339 aroA-2 aroA-2 fdnG-1 fdnG-1 DVU_0588 DVU_0588 acs acs DVU_0765 DVU_0765 DVU_0889 DVU_0889 glyA glyA DVU_1412 DVU_1412 glpX glpX gpmA gpmA DVU_1772 DVU_1772 DVU_1833 DVU_1833 fbp fbp pfkA pfkA cooS cooS fba fba DVU_2250 DVU_2250 cooF cooF hdrA hdrA hdrB hdrB hdrC hdrC DVU_2481 DVU_2481 fdnG-2 fdnG-2 DVU_2739 DVU_2739 DVU_2811 DVU_2811 fdnG-3 fdnG-3 gpm gpm acsA acsA pta pta ackA ackA DVU_3121 DVU_3121 DVU_3214 DVU_3214 DVU_3237 DVU_3237
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVU_0152Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P42850; match to protein family HMM PF00391; match to protein family HMM PF01326. (853 aa)
DVU_0246Pyruvate phosphate dikinase, PEP/pyruvate binding domain protein; Identified by similarity to SP:O29548; match to protein family HMM PF00391; match to protein family HMM PF01326. (744 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (437 aa)
DVU_0339D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (301 aa)
aroA-2Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids; Belongs to the DeoC/FbaB aldolase family. ADHS subfamily. (266 aa)
fdnG-1Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553. (1005 aa)
DVU_0588Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (236 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (648 aa)
DVU_0765Hydroxypyruvate reductase, putative; Identified by similarity to SP:Q44472; match to protein family HMM PF05161. (454 aa)
DVU_0889Phosphonopyruvate decarboxylase-related protein; Identified by match to protein family HMM PF01676. (379 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family. (412 aa)
DVU_1412D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
glpXFructose-1,6-bisphosphatase, class II; Identified by similarity to SP:P28860; match to protein family HMM PF03320; match to protein family HMM TIGR00330; Belongs to the FBPase class 2 family. (327 aa)
gpmAPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
DVU_1772Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070. (673 aa)
DVU_1833Phosphoenolpyruvate synthase, putative; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896. (1191 aa)
fbpFructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. (337 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (444 aa)
cooSCarbon monoxide dehydrogenase; Identified by similarity to SP:P31896. (629 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; Identified by similarity to SP:P13243; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (307 aa)
DVU_2250Identified by match to protein family HMM PF00501. (551 aa)
cooFIron-sulfur protein CooF; Identified by similarity to SP:P31894; match to protein family HMM PF00037. (173 aa)
hdrAHeterodisulfide reductase, A subunit; Identified by similarity to GP:12642418; match to protein family HMM PF00037. (652 aa)
hdrBHeterodisulfide reductase, B subunit; Identified by similarity to GP:3378542; match to protein family HMM PF02754. (334 aa)
hdrCHeterodisulfide reductase, C subunit; Identified by similarity to GP:12642421. (186 aa)
DVU_2481Formate dehydrogenase, beta subunit, putative; Identified by similarity to SP:P32175. (260 aa)
fdnG-2Formate dehydrogenase, alpha subunit, selenocysteine-containing; Selenoprotein; identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1003 aa)
DVU_2739Pyruvate phosphate dikinase, PEP/pyruvate binding domain protein; Identified by similarity to SP:O29548; match to protein family HMM PF00391; match to protein family HMM PF01326. (945 aa)
DVU_2811Formate dehydrogenase, beta subunit, putative; Beta chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The beta chain is an electron transfer unit. (219 aa)
fdnG-3Formate dehydrogenase, alpha subunit, selenocysteine-containing; Alpha chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The alpha subunit of formate dehydrogenase forms the active site. (1012 aa)
gpmPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
acsAacetoacetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (661 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. (704 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
DVU_3121Aminotransferase, class V; Identified by match to protein family HMM PF00266. (376 aa)
DVU_3214Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P42850; match to protein family HMM PF00391; match to protein family HMM PF01326. (884 aa)
DVU_3237Phosphoenolpyruvate synthase-related protein; Identified by similarity to SP:P23538; match to protein family HMM PF00391. (773 aa)
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
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