node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHO82411.1 | EHO82421.1 | HMPREF0380_01652 | HMPREF0380_01662 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | Hypothetical protein. | 0.489 |
EHO82411.1 | EHO85252.1 | HMPREF0380_01652 | HMPREF0380_00977 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.645 |
EHO82411.1 | dxr | HMPREF0380_01652 | HMPREF0380_01661 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.973 |
EHO82411.1 | ispDF | HMPREF0380_01652 | HMPREF0380_00049 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | Hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.882 |
EHO82411.1 | ispE | HMPREF0380_01652 | HMPREF0380_00347 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.960 |
EHO82411.1 | ispG | HMPREF0380_01652 | HMPREF0380_01664 | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.895 |
EHO82421.1 | EHO82411.1 | HMPREF0380_01662 | HMPREF0380_01652 | Hypothetical protein. | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 0.489 |
EHO82421.1 | EHO85252.1 | HMPREF0380_01662 | HMPREF0380_00977 | Hypothetical protein. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.441 |
EHO82421.1 | dxr | HMPREF0380_01662 | HMPREF0380_01661 | Hypothetical protein. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.727 |
EHO82421.1 | ispDF | HMPREF0380_01662 | HMPREF0380_00049 | Hypothetical protein. | Hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.917 |
EHO82421.1 | ispG | HMPREF0380_01662 | HMPREF0380_01664 | Hypothetical protein. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.829 |
EHO85252.1 | EHO82411.1 | HMPREF0380_00977 | HMPREF0380_01652 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 0.645 |
EHO85252.1 | EHO82421.1 | HMPREF0380_00977 | HMPREF0380_01662 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Hypothetical protein. | 0.441 |
EHO85252.1 | dxr | HMPREF0380_00977 | HMPREF0380_01661 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.622 |
EHO85252.1 | ispDF | HMPREF0380_00977 | HMPREF0380_00049 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.828 |
EHO85252.1 | ispE | HMPREF0380_00977 | HMPREF0380_00347 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.720 |
EHO85252.1 | ispG | HMPREF0380_00977 | HMPREF0380_01664 | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.966 |
dxr | EHO82411.1 | HMPREF0380_01661 | HMPREF0380_01652 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hypothetical protein; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily. | 0.973 |
dxr | EHO82421.1 | HMPREF0380_01661 | HMPREF0380_01662 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hypothetical protein. | 0.727 |
dxr | EHO85252.1 | HMPREF0380_01661 | HMPREF0380_00977 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.622 |