(28 nodes) Endoderm formation network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOG	Noggin; Belongs to the noggin family. (223 aa)
	MMP15	ZnMc domain-containing protein. (651 aa)
	CDC73	Cell division cycle 73. (531 aa)
	MMP2	Matrix metallopeptidase 2. (663 aa)
	DUSP5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	SETD2	Uncharacterized protein. (582 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (962 aa)
	LHX1	LIM homeobox 1. (333 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (894 aa)
	LAMB3	Laminin subunit beta 3. (1255 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (998 aa)
	RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component. (700 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3076 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa)
	ENSAPLP00000017124	ZnMc domain-containing protein. (190 aa)
	LHX5	LIM homeobox 5. (297 aa)
	DKK1	Dickkopf WNT signaling pathway inhibitor 1. (271 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (282 aa)
	MIXL1	Mix paired-like homeobox. (250 aa)
	ENSAPLP00000028106	DUF3377 domain-containing protein. (323 aa)
	HMGA2	Uncharacterized protein. (202 aa)
	LEO1	LEO1 homolog, Paf1/RNA polymerase II complex component. (696 aa)
	DUSP4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (449 aa)
	EOMES	Eomesodermin. (746 aa)
	HNF1B	HNF1 homeobox B. (691 aa)
	SOX7	Uncharacterized protein. (558 aa)
	ENSAPLP00000032827	Uncharacterized protein. (93 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CTNNB1	ENSAPLP00000002993	ENSAPLP00000013346	Cell division cycle 73.	Catenin beta 1.	0.815
CDC73	CTR9	ENSAPLP00000002993	ENSAPLP00000004957	Cell division cycle 73.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	LEO1	ENSAPLP00000002993	ENSAPLP00000029699	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	RTF1	ENSAPLP00000002993	ENSAPLP00000012906	Cell division cycle 73.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.996
CDC73	SETD2	ENSAPLP00000002993	ENSAPLP00000004480	Cell division cycle 73.	Uncharacterized protein.	0.552
CTNNB1	CDC73	ENSAPLP00000013346	ENSAPLP00000002993	Catenin beta 1.	Cell division cycle 73.	0.815
CTNNB1	DKK1	ENSAPLP00000013346	ENSAPLP00000021199	Catenin beta 1.	Dickkopf WNT signaling pathway inhibitor 1.	0.569
CTNNB1	EOMES	ENSAPLP00000013346	ENSAPLP00000030390	Catenin beta 1.	Eomesodermin.	0.477
CTNNB1	LEO1	ENSAPLP00000013346	ENSAPLP00000029699	Catenin beta 1.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.691
CTNNB1	SOX7	ENSAPLP00000013346	ENSAPLP00000032715	Catenin beta 1.	Uncharacterized protein.	0.781
CTR9	CDC73	ENSAPLP00000004957	ENSAPLP00000002993	CTR9 homolog, Paf1/RNA polymerase II complex component.	Cell division cycle 73.	0.999
CTR9	LEO1	ENSAPLP00000004957	ENSAPLP00000029699	CTR9 homolog, Paf1/RNA polymerase II complex component.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CTR9	RTF1	ENSAPLP00000004957	ENSAPLP00000012906	CTR9 homolog, Paf1/RNA polymerase II complex component.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.997
CTR9	SETD2	ENSAPLP00000004957	ENSAPLP00000004480	CTR9 homolog, Paf1/RNA polymerase II complex component.	Uncharacterized protein.	0.640
DKK1	CTNNB1	ENSAPLP00000021199	ENSAPLP00000013346	Dickkopf WNT signaling pathway inhibitor 1.	Catenin beta 1.	0.569
ENSAPLP00000017124	ENSAPLP00000028106	ENSAPLP00000017124	ENSAPLP00000028106	ZnMc domain-containing protein.	DUF3377 domain-containing protein.	0.874
ENSAPLP00000028106	ENSAPLP00000017124	ENSAPLP00000028106	ENSAPLP00000017124	DUF3377 domain-containing protein.	ZnMc domain-containing protein.	0.874
EOMES	CTNNB1	ENSAPLP00000030390	ENSAPLP00000013346	Eomesodermin.	Catenin beta 1.	0.477
EOMES	MIXL1	ENSAPLP00000030390	ENSAPLP00000023751	Eomesodermin.	Mix paired-like homeobox.	0.608
ITGA4	ITGB5	ENSAPLP00000011456	ENSAPLP00000007149	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.959