STRINGSTRING
U3IBK2_ANAPP U3IBK2_ANAPP RIPK2 RIPK2 MAP3K13 MAP3K13 MAP3K14 MAP3K14 MAP3K15 MAP3K15 MAP3K20-2 MAP3K20-2 MAP3K8 MAP3K8 MAP3K4 MAP3K4 MAP3K21 MAP3K21 MAP3K9 MAP3K9 MAP3K5 MAP3K5 LRRK2 LRRK2 MAP3K2 MAP3K2 MAP3K20 MAP3K20 MAP3K6 MAP3K6 RIPK1 RIPK1 BRAF BRAF RAF1 RAF1 MAP3K1 MAP3K1 MAP3K7 MAP3K7 MOS MOS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U3IBK2_ANAPPUncharacterized protein. (566 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (955 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (944 aa)
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1342 aa)
MAP3K20-2SAM domain-containing protein. (549 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1564 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1098 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (888 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1219 aa)
LRRK2Leucine rich repeat kinase 2. (2534 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (624 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (452 aa)
MAP3K6Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (492 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (755 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (676 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1525 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (644 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.