59 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FCHSD2	FCH and double SH3 domains 2. (743 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (488 aa)
	STON1	Stonin-1; May be involved in the endocytic machinery. (722 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1188 aa)
	REPS1	RALBP1 associated Eps domain containing 1. (797 aa)
	CUBN	Cubilin. (3620 aa)
	EPS15	Epidermal growth factor receptor pathway substrate 15. (883 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	CTTN	Cortactin. (516 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (429 aa)
	ITSN1	Intersectin 1. (1712 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1000 aa)
	APP	Amyloid beta precursor protein. (717 aa)
	FCHO2	FCH domain only 2. (1057 aa)
	DAB2	DAB adaptor protein 2. (715 aa)
	U3IWK3_ANAPP	Uncharacterized protein. (578 aa)
	U3J393_ANAPP	ENTH domain-containing protein. (682 aa)
	OCRL	IPPc domain-containing protein. (692 aa)
	U3J7G1_ANAPP	Uncharacterized protein. (861 aa)
	ENSAPLP00000016508	Uncharacterized protein. (182 aa)
	ENSAPLP00000016684	Clat_adaptor_s domain-containing protein. (133 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (185 aa)
	ENSAPLP00000016890	HSac2 domain-containing protein. (138 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
	ENSAPLP00000017795	Rho-GAP domain-containing protein. (189 aa)
	CLHC1	Clathrin heavy chain linker domain-containing protein 1. (552 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (247 aa)
	ENSAPLP00000019451	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1304 aa)
	MYO6	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1216 aa)
	ENSAPLP00000019823	Uncharacterized protein. (297 aa)
	SORT1	Sortilin. (574 aa)
	ENSAPLP00000020593	EGF-like domain-containing protein. (460 aa)
	INPP5F	SAC domain-containing protein. (246 aa)
	LRP1B	LDL receptor related protein 1B. (4290 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	ENSAPLP00000021296	Uncharacterized protein. (608 aa)
	ENSAPLP00000021662	Uncharacterized protein. (72 aa)
	LRP1	Uncharacterized protein. (522 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1. (445 aa)
	AAK1	AP2 associated kinase 1. (1290 aa)
	ENSAPLP00000024089	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (163 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (750 aa)
	ENSAPLP00000025140	MHD domain-containing protein. (177 aa)
	ENSAPLP00000026276	SAC domain-containing protein. (479 aa)
	AMN	Amnion associated transmembrane protein. (525 aa)
	ENSAPLP00000027309	Uncharacterized protein. (237 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (714 aa)
	RAB35	RAB35, member RAS oncogene family. (204 aa)
	ENSAPLP00000028515	Uncharacterized protein. (353 aa)
	SNAP91	Synaptosome associated protein 91. (795 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
	EPS15L1	Epidermal growth factor receptor pathway substrate 15 like 1. (932 aa)
	ITSN2	Uncharacterized protein. (1178 aa)
	FNBP1	Formin binding protein 1. (585 aa)
	SH3BP4	SH3 domain binding protein 4. (786 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa)
	ENSAPLP00000032201	Uncharacterized protein. (92 aa)
	EPN3	Epsin 3. (473 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	AP2M1	ENSAPLP00000023130	ENSAPLP00000006303	AP2 associated kinase 1.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.779
AAK1	CLHC1	ENSAPLP00000023130	ENSAPLP00000018004	AP2 associated kinase 1.	Clathrin heavy chain linker domain-containing protein 1.	0.480
AAK1	CLTA	ENSAPLP00000023130	ENSAPLP00000019334	AP2 associated kinase 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.454
AAK1	CLTC	ENSAPLP00000023130	ENSAPLP00000031758	AP2 associated kinase 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.503
AAK1	CLTCL1	ENSAPLP00000023130	ENSAPLP00000021207	AP2 associated kinase 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.503
AAK1	DAB2	ENSAPLP00000023130	ENSAPLP00000008982	AP2 associated kinase 1.	DAB adaptor protein 2.	0.609
AAK1	ENSAPLP00000024089	ENSAPLP00000023130	ENSAPLP00000024089	AP2 associated kinase 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.454
AAK1	ENSAPLP00000025140	ENSAPLP00000023130	ENSAPLP00000025140	AP2 associated kinase 1.	MHD domain-containing protein.	0.470
AAK1	ENSAPLP00000028515	ENSAPLP00000023130	ENSAPLP00000028515	AP2 associated kinase 1.	Uncharacterized protein.	0.518
AAK1	EPN3	ENSAPLP00000023130	ENSAPLP00000032379	AP2 associated kinase 1.	Epsin 3.	0.412
AAK1	EPS15	ENSAPLP00000023130	ENSAPLP00000003907	AP2 associated kinase 1.	Epidermal growth factor receptor pathway substrate 15.	0.740
AAK1	EPS15L1	ENSAPLP00000023130	ENSAPLP00000029591	AP2 associated kinase 1.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.740
AAK1	FCHO2	ENSAPLP00000023130	ENSAPLP00000008943	AP2 associated kinase 1.	FCH domain only 2.	0.453
AAK1	HIP1R	ENSAPLP00000023130	ENSAPLP00000002214	AP2 associated kinase 1.	Huntingtin interacting protein 1 related.	0.753
AAK1	ITSN2	ENSAPLP00000023130	ENSAPLP00000030081	AP2 associated kinase 1.	Uncharacterized protein.	0.518
AAK1	PICALM	ENSAPLP00000023130	ENSAPLP00000027330	AP2 associated kinase 1.	Phosphatidylinositol binding clathrin assembly protein.	0.767
AAK1	REPS1	ENSAPLP00000023130	ENSAPLP00000002740	AP2 associated kinase 1.	RALBP1 associated Eps domain containing 1.	0.815
AAK1	SGIP1	ENSAPLP00000023130	ENSAPLP00000022657	AP2 associated kinase 1.	SH3 domain GRB2 like endophilin interacting protein 1.	0.470
AAK1	SNAP91	ENSAPLP00000023130	ENSAPLP00000028627	AP2 associated kinase 1.	Synaptosome associated protein 91.	0.561
AAK1	U3J393_ANAPP	ENSAPLP00000023130	ENSAPLP00000013970	AP2 associated kinase 1.	ENTH domain-containing protein.	0.611