34 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TIFA	TRAF interacting protein with forkhead associated domain. (119 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (469 aa)
	ASH1L	ASH1 like histone lysine methyltransferase. (3028 aa)
	EDN1	Endothelin 1. (203 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
	REL	REL proto-oncogene, NF-kB subunit. (592 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (191 aa)
	TNFSF11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
	U3IBK2_ANAPP	Uncharacterized protein. (566 aa)
	FYN	Tyrosine-protein kinase. (534 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
	NLRC3	NLR family CARD domain containing 3. (1188 aa)
	AZI2	5-azacytidine induced 2. (407 aa)
	ROCK2	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1488 aa)
	U3IYY5_ANAPP	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (480 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (944 aa)
	IRAK1BP1	Interleukin 1 receptor associated kinase 1 binding protein 1. (261 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	CARD11	Caspase recruitment domain family member 11. (1187 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (731 aa)
	BCL10	CARD domain-containing protein. (316 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (191 aa)
	TIRAP	TIR domain containing adaptor protein. (219 aa)
	CARD9	Caspase recruitment domain family member 9. (518 aa)
	TANK	TRAF family member associated NFKB activator. (481 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
	FAIM	Fas apoptotic inhibitory molecule. (179 aa)
	ENSAPLP00000027200	Uncharacterized protein. (271 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (757 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (644 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (951 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AZI2	CHUK	ENSAPLP00000030757	ENSAPLP00000024759	5-azacytidine induced 2.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.548
AZI2	IKBKB	ENSAPLP00000030757	ENSAPLP00000029764	5-azacytidine induced 2.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.548
AZI2	TANK	ENSAPLP00000030757	ENSAPLP00000007526	5-azacytidine induced 2.	TRAF family member associated NFKB activator.	0.488
BCL10	CARD11	ENSAPLP00000002985	ENSAPLP00000003269	CARD domain-containing protein.	Caspase recruitment domain family member 11.	0.948
BCL10	CARD9	ENSAPLP00000002985	ENSAPLP00000007223	CARD domain-containing protein.	Caspase recruitment domain family member 9.	0.916
BCL10	CHUK	ENSAPLP00000002985	ENSAPLP00000024759	CARD domain-containing protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.737
BCL10	IKBKB	ENSAPLP00000002985	ENSAPLP00000029764	CARD domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.979
BCL10	MAP3K7	ENSAPLP00000002985	ENSAPLP00000024103	CARD domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7.	0.600
BCL10	REL	ENSAPLP00000002985	ENSAPLP00000006397	CARD domain-containing protein.	REL proto-oncogene, NF-kB subunit.	0.550
BCL10	RIPK2	ENSAPLP00000002985	ENSAPLP00000006481	CARD domain-containing protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.517
BCL10	TRAF6	ENSAPLP00000002985	ENSAPLP00000027926	CARD domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.789
CARD11	BCL10	ENSAPLP00000003269	ENSAPLP00000002985	Caspase recruitment domain family member 11.	CARD domain-containing protein.	0.948
CARD11	CARD9	ENSAPLP00000003269	ENSAPLP00000007223	Caspase recruitment domain family member 11.	Caspase recruitment domain family member 9.	0.564
CARD11	CHUK	ENSAPLP00000003269	ENSAPLP00000024759	Caspase recruitment domain family member 11.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.794
CARD11	IKBKB	ENSAPLP00000003269	ENSAPLP00000029764	Caspase recruitment domain family member 11.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.655
CARD11	MAP3K7	ENSAPLP00000003269	ENSAPLP00000024103	Caspase recruitment domain family member 11.	Mitogen-activated protein kinase kinase kinase 7.	0.802
CARD11	REL	ENSAPLP00000003269	ENSAPLP00000006397	Caspase recruitment domain family member 11.	REL proto-oncogene, NF-kB subunit.	0.460
CARD11	RIPK2	ENSAPLP00000003269	ENSAPLP00000006481	Caspase recruitment domain family member 11.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.463
CARD11	TRAF6	ENSAPLP00000003269	ENSAPLP00000027926	Caspase recruitment domain family member 11.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.777
CARD11	U3IBK2_ANAPP	ENSAPLP00000003269	ENSAPLP00000004624	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.463