STRINGSTRING
GREM1 GREM1 BMP2 BMP2 NOG NOG SMAD7 SMAD7 SMAD4 SMAD4 LOXL2 LOXL2 U3IGU3_ANAPP U3IGU3_ANAPP USF3 USF3 MTOR MTOR LEF1 LEF1 DAB2 DAB2 JAG1 JAG1 BAMBI BAMBI EFNA1 EFNA1 RGCC RGCC TGFBR1 TGFBR1 GATA3 GATA3 GLIPR2 GLIPR2 TBX20 TBX20 ZNF750 ZNF750 TGFB2 TGFB2 TGFB3 TGFB3 OLFM3 OLFM3 SOX9 SOX9 CTNNB1 CTNNB1 POFUT2 POFUT2 MDK MDK PHLDB1 PHLDB1 TGFBR2 TGFBR2 ENSAPLP00000020265 ENSAPLP00000020265 IL6 IL6 DAG1 DAG1 CLASP2 CLASP2 ENSAPLP00000023501 ENSAPLP00000023501 ACVR1 ACVR1 OLFM1 OLFM1 ENSAPLP00000026729 ENSAPLP00000026729 PHLDB2 PHLDB2 PAWR PAWR ENSAPLP00000029980 ENSAPLP00000029980 CLASP1 CLASP1 SPRED1 SPRED1 ENSAPLP00000032903 ENSAPLP00000032903
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GREM1Gremlin. (184 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
SMAD7Mothers against decapentaplegic homolog. (369 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
LOXL2Lysyl oxidase like 2. (789 aa)
U3IGU3_ANAPPB30.2/SPRY domain-containing protein. (185 aa)
USF3Upstream transcription factor family member 3. (1876 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
LEF1Uncharacterized protein. (415 aa)
DAB2DAB adaptor protein 2. (715 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1225 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
RGCCRegulator of cell cycle. (133 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
GATA3GATA binding protein 3. (712 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (123 aa)
TBX20Uncharacterized protein. (417 aa)
ZNF750Zinc finger protein 750. (714 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TGFB3Transforming growth factor beta 3. (458 aa)
OLFM3Olfactomedin 3. (458 aa)
SOX9SRY-box transcription factor 9. (489 aa)
CTNNB1Catenin beta 1. (781 aa)
POFUT2Protein O-fucosyltransferase 2. (439 aa)
MDKMidkine. (142 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1372 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (575 aa)
ENSAPLP00000020265Uncharacterized protein. (462 aa)
IL6Uncharacterized protein. (350 aa)
DAG1Dystroglycan 1. (896 aa)
CLASP2Cytoplasmic linker associated protein 2. (1466 aa)
ENSAPLP00000023501SRCR domain-containing protein. (269 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (526 aa)
OLFM1Noelin-1 domain-containing protein. (95 aa)
ENSAPLP00000026729Noelin-1 domain-containing protein. (91 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1349 aa)
PAWRPro-apoptotic WT1 regulator. (208 aa)
ENSAPLP00000029980Uncharacterized protein. (148 aa)
CLASP1Cytoplasmic linker associated protein 1. (1540 aa)
SPRED1Sprouty related EVH1 domain containing 1. (414 aa)
ENSAPLP00000032903HMG box domain-containing protein. (180 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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