STRINGSTRING
ENSAPLP00000020265 ENSAPLP00000020265 IL6 IL6 ENSAPLP00000023501 ENSAPLP00000023501 ACVR1 ACVR1 OLFM1 OLFM1 ENSAPLP00000026729 ENSAPLP00000026729 ENSAPLP00000032903 ENSAPLP00000032903 MDK MDK CTNNB1 CTNNB1 SOX9 SOX9 OLFM3 OLFM3 TGFB3 TGFB3 TGFB2 TGFB2 TBX20 TBX20 GLIPR2 GLIPR2 TGFBR1 TGFBR1 RGCC RGCC BAMBI BAMBI JAG1 JAG1 DAB2 DAB2 LEF1 LEF1 MTOR MTOR LOXL2 LOXL2 SMAD4 SMAD4 BMP2 BMP2 TGFBR2 TGFBR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAPLP00000020265Uncharacterized protein. (462 aa)
IL6Uncharacterized protein. (350 aa)
ENSAPLP00000023501SRCR domain-containing protein. (269 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (526 aa)
OLFM1Noelin-1 domain-containing protein. (95 aa)
ENSAPLP00000026729Noelin-1 domain-containing protein. (91 aa)
ENSAPLP00000032903HMG box domain-containing protein. (180 aa)
MDKMidkine. (142 aa)
CTNNB1Catenin beta 1. (781 aa)
SOX9SRY-box transcription factor 9. (489 aa)
OLFM3Olfactomedin 3. (458 aa)
TGFB3Transforming growth factor beta 3. (458 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TBX20Uncharacterized protein. (417 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (123 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
RGCCRegulator of cell cycle. (133 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1225 aa)
DAB2DAB adaptor protein 2. (715 aa)
LEF1Uncharacterized protein. (415 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
LOXL2Lysyl oxidase like 2. (789 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (575 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.